![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Ben on November 27, 2011, at 23:49:40
I read in a good book that Valproate inhibits the elimination of Clonzapam. Unfortunately there was no source in the book about this info. Did you know that and have you some further info?
Posted by SLS on November 28, 2011, at 6:53:50
In reply to Valproate - Clonazepam interaction?!, posted by Ben on November 27, 2011, at 23:49:40
> I read in a good book that Valproate inhibits the elimination of Clonzapam. Unfortunately there was no source in the book about this info. Did you know that and have you some further info?
-----------------------------------------
http://www.ncbi.nlm.nih.gov/pubmed/14651674"Concomitant administration of clonazepam and valproic acid resulted in a 14% increase in clonazepam clearance, and a 17.9% decrease in valproic acid clearance."
- Scott
Posted by SLS on November 28, 2011, at 7:10:29
In reply to Re: Valproate - Clonazepam interaction?!, posted by SLS on November 28, 2011, at 6:53:50
> > I read in a good book that Valproate inhibits the elimination of Clonzapam. Unfortunately there was no source in the book about this info. Did you know that and have you some further info?
>
> -----------------------------------------
>
>
> http://www.ncbi.nlm.nih.gov/pubmed/14651674
>
> "Concomitant administration of clonazepam and valproic acid resulted in a 14% increase in clonazepam clearance, and a 17.9% decrease in valproic acid clearance."
These guys may have it 180° backwards.
----------------------------------------------I found this:
http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZGYZ805.001.htm
"The results showed that sodium valproate increased the concentration of clonazepam at every time point.
----------------------------------------------
- Scott
Posted by Phillipa on November 28, 2011, at 9:43:55
In reply to Re: Valproate - Clonazepam interaction?!, posted by SLS on November 28, 2011, at 7:10:29
Reminds me of luvox and how it increased amounts of benzos are a lot of meds like this also? Phillipa
Posted by Phillipa on December 4, 2011, at 10:43:58
In reply to Re: Valproate - Clonazepam interaction?!, posted by SLS on November 28, 2011, at 6:53:50
Babble is up and running again thanks to Dr Bob Phillipa
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.