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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by tensor on November 12, 2011, at 9:29:53
I am on day three with Seroquel, took 100mg yesterday. I take it for TRD and anxiety, not really feeling much of it yet, no sleepiness, no sugar cravings. Wondering how long before it kicks in and what dose I should aim for. Input appreciated.
Posted by Phillipa on November 12, 2011, at 9:57:25
In reply to Seroquel for MDD, posted by tensor on November 12, 2011, at 9:29:53
12.5mg knocked me out the first time took it. One night at 50mg and they dicontinued it for me as was too strong for me. Some say the higher doses are less sedating? Phillipa
Posted by Christ_empowered on November 12, 2011, at 11:50:06
In reply to Seroquel for MDD, posted by tensor on November 12, 2011, at 9:29:53
Aim for the lowest dose to suppress your symptoms. The LED (lowest effective dose) is what psychiatrists are supposed to aim for with any antipsychotic, even the "atypicals," and even when dealing with schizophrenia or severe bipolar I. All too often, docs (and patients) get fixated on achieving a "target dose." Some people can do fine on low dose (even as-needed) antipsychotics; others require higher doses, especially during periods of crisis and stress.
Posted by ed_uk2010 on November 12, 2011, at 14:21:41
In reply to Seroquel for MDD, posted by tensor on November 12, 2011, at 9:29:53
> I am on day three with Seroquel, took 100mg yesterday. I take it for TRD and anxiety, not really feeling much of it yet, no sleepiness, no sugar cravings. Wondering how long before it kicks in and what dose I should aim for. Input appreciated.
>
>Hi M,
I guess that since your body is used to antihistamine-type meds such as mirtazapine, Seroquel will be less likely to cause drowsiness.
Posted by tensor on November 13, 2011, at 3:26:27
In reply to Re: Seroquel for MDD, posted by ed_uk2010 on November 12, 2011, at 14:21:41
> Hi M,
>
> I guess that since your body is used to antihistamine-type meds such as mirtazapine, Seroquel will be less likely to cause drowsiness.
>
>Hi Ed,
Yes I know, it's the same with tricyclics. Day four now and I feel a little jittery when I wake up, that's all.
Posted by ed_uk2010 on November 13, 2011, at 11:43:44
In reply to Re: Seroquel for MDD » ed_uk2010, posted by tensor on November 13, 2011, at 3:26:27
>Day four now and I feel a little jittery when I wake up, that's all.
Hi M,
Nice to see your name on here.. but not so good to know that you're ill right now.
Let us know how Seroquel goes for you.
Ed
Posted by mellow on November 14, 2011, at 1:33:37
In reply to Seroquel for MDD, posted by tensor on November 12, 2011, at 9:29:53
I have done very well with atypicals. Havent done seroquel. Insurance wouldnt cover it. Risperdal has brought me back from pure madness one a couple of occasions though. Im not sure if the two are totally comparable but, I would give it a couple of weeks to build up in your system. For me it always takes a couple of days to slow down the agitation and start working as a good sleep aid. In my opinion it's the sleep and sedation factor that make them a powerful class of drugs. After a week or so you should feel a lot calmer and clear headed. If not try something else, but I wouldn't abandon it until you've given it some time.
Also if the sedation is too much try a strong cup of coffee in the morning. It helps!
mellow
Posted by Phidippus on November 15, 2011, at 20:12:32
In reply to Seroquel for MDD, posted by tensor on November 12, 2011, at 9:29:53
Seroquel is a medicine that takes effect pretty quickly. If you didn't experience a lot of sedation, that's good. Seroquel really should be used along with an antidepressant, rather than on its own. The mechanism through which Seroquel helps with depression is by exerting effects on the NET (norepinephrine transport), effectively increasing norepinephrine levels in the brain. It doesn't raise seratonin levels, which is pretty important in treating depression.
Eric
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