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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by roscopeeco on August 30, 2011, at 14:57:09
http://www.nih.gov/news/health/jun2011/nimh-22.htm
This was a pretty interesting article just submitted July of this year. Talks about a more direct route to alleviating depression. Hopefully, drugs are in various stages of trials to incorporate this new finding.
Posted by roscopeeco on August 30, 2011, at 18:20:08
In reply to New research on boosting the response of ADs, posted by roscopeeco on August 30, 2011, at 14:57:09
I would like to hear SLS (Scott's take on this research). If any of the readers have access to him ask him to read and give us his thoughts.
Thanks for your input,
Jesse
Posted by mellow on August 30, 2011, at 18:20:50
In reply to New research on boosting the response of ADs, posted by roscopeeco on August 30, 2011, at 14:57:09
Very cool thanks for the article. I'm certain there will be alternatives for drug therapy in the future. Of course they probably can't just put ketamine out on the market so they will have to use the knowledge of that pathway and find another agent to trigger that response. They will need something that doesn't have street value or act like a lethal tranquilizer when used in excess. I've seen people almost die by overdoing it with ketamine back in my party days.
Of course what angers me is that newer drugs could come out tomorrow if nami, nih, narsad were allowed to publish what they really know. SSRI's have probably peaked, but big pharma can probably make a few more trillions on Cymbalta, Lyrica and such. Kind of like how they did the bait and switch with Lexapro after Celexa went generic. We won't see anything new until all the NRI drugs get resynthesized for one more generation and then finally go generic. I'm thinking at least another 15 or 20 years.
Not to sound like a downer, but there are people who stand to lose money if research like the stuff in that article were to bring drugs to market before current patents are up.
mellow
Posted by roscopeeco on August 30, 2011, at 18:43:39
In reply to Re: New research on boosting the response of ADs, posted by mellow on August 30, 2011, at 18:20:50
That is the irony of it all. There has to be a way to do something about the theory you explained. It is not necessarily a theory, there is some truth in what you say for sure. I have always theorized why drugs don't have better efficacy considering what we have now discovered about the human brain. Combine that knowledge with what we know works on the street and surely researches can come up with drugs that work for more of the population.
If I were a pharma company, I would jump at research like this to be first to market for a truly novel drug. Maybe some European pharm company will pick it up and run with the research. Who knows.
This is the end of the thread.
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