Psycho-Babble Medication Thread 994431

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Anyone try low dose Amisulpride or Sulpride

Posted by poser938 on August 21, 2011, at 4:50:56

how was your experience?
i'm considering trying it for chronic dopamine agonist withdrawal syndrome (DAWS). i have severe anhedonia and am unable to think clearly.

 

Re: Anyone try low dose Amisulpride or Sulpride

Posted by bleauberry on August 21, 2011, at 19:05:04

In reply to Anyone try low dose Amisulpride or Sulpride, posted by poser938 on August 21, 2011, at 4:50:56

I've been on and off amisulpride multiple times. My opinion is it would be a good match for your situation. The trick with it is in the dosing. The lowest dose used in most studies was 50mg, but that can be much. Even 25mg is fairly potent. I usually start it by taking 25mg once very other day for a week and then every day after that. 12.5mg wasn't enough, 50mg was too much. To me the feeling of the drug goes like this....the first day there is some mild stimulation both physically and mentally, not as strong the second day, and then disappears....the real effect will now wait for another few weeks to kick in gradually. To me this drug is a rapid antidepressant that can be used on an as-needed basis for same day results (thus one of my few emergency meds), and is somewhat stimulating yet calming at the same time and it does help with cognitive function and creativity. I found it to be a better anti-anhedonia med than antidepressant med, but that part of it takes 6 weeks or so to fully take effect.

 

Re: Anyone try low dose Amisulpride or Sulpride

Posted by poser938 on August 21, 2011, at 22:14:38

In reply to Re: Anyone try low dose Amisulpride or Sulpride, posted by bleauberry on August 21, 2011, at 19:05:04

thanks for your reply. it's good to hear it can help in the areas you described. my problem comes from taking mirapex back at the end of 2009. for the 1st few weeks on it i had the benefit of increased sensitivity in the libido area but then this all the sudden reversed and i developed some pretty bad anhedonia. then, just yesterday i read that mirapex stimulates D2/D3 autoreceptors therefore causing a decrease in the dopamine your brain produces, so im hoping if block off those receptors, that it will work to make me feel better. i'm glad you also think amisulpride would be good in my case and i'll probably start out taking just fraction of the smallest mg pill, im nervous as heck about medicine, and work my way up from there.

i took ritalin, one time, because its supposed to be good for anhedonia but i think the mirapex made me intolerant of dopamiine meds since, i do believe, they all stimulate dopamine autoreceptors.

 

Re: Anyone try low dose Amisulpride or Sulpride

Posted by poser938 on August 21, 2011, at 23:02:58

In reply to Re: Anyone try low dose Amisulpride or Sulpride, posted by bleauberry on August 21, 2011, at 19:05:04

Also, is amisulpride available where you live or do you order it? im in america and its not avilable here. so if you order it can you recommend a good site?


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