Psycho-Babble Medication Thread 981982

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Half-life and steady-state plasma levels

Posted by NKP on April 5, 2011, at 0:05:18

A drug (low dose Fluanxol) with a half-life of 36 hours is taken every other day. How long until steady-state plasma levels are reached?

 

Re: Half-life and steady-state plasma levels

Posted by Brainbeard on April 5, 2011, at 16:28:23

In reply to Half-life and steady-state plasma levels, posted by NKP on April 5, 2011, at 0:05:18

> A drug (low dose Fluanxol) with a half-life of 36 hours is taken every other day. How long until steady-state plasma levels are reached?

About a week. I'm on 0.5mg Fluanxol myself.

 

Re: Half-life and steady-state plasma levels » Brainbeard

Posted by NKP on April 9, 2011, at 15:51:48

In reply to Re: Half-life and steady-state plasma levels, posted by Brainbeard on April 5, 2011, at 16:28:23

> > A drug (low dose Fluanxol) with a half-life of 36 hours is taken every other day. How long until steady-state plasma levels are reached?
>
> About a week. I'm on 0.5mg Fluanxol myself.
>
>

Thank you very much.

 

Re: Half-life and steady-state plasma levels

Posted by Brainbeard on April 9, 2011, at 16:05:25

In reply to Re: Half-life and steady-state plasma levels » Brainbeard, posted by NKP on April 9, 2011, at 15:51:48

O sorry, I didn't see the 'every other day' part. Make that two weeks.

 

Re: Half-life and steady-state plasma levels

Posted by jono_in_adelaide on April 11, 2011, at 22:57:41

In reply to Re: Half-life and steady-state plasma levels » Brainbeard, posted by NKP on April 9, 2011, at 15:51:48

General rule is 5 half lives until steady state.

 

Re: Half-life and steady-state plasma levels

Posted by Brainbeard on April 12, 2011, at 10:25:37

In reply to Re: Half-life and steady-state plasma levels, posted by jono_in_adelaide on April 11, 2011, at 22:57:41

> General rule is 5 half lives until steady state.

Ah, that was it, couldn't remember/find it back.


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