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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by psychobot5000 on March 25, 2011, at 12:05:33
Apparently this is a somewhat sedating med with a reasonably short half-life, that has some similarities, in its mechanism of action, to GHB--yet I can't find any mention of its being used as a hypnotic. Anyone have any insight on this?
If Xyrem is so effective, it would seem to me that other meds that hit the same target (i.e. agonize GABA B receptors), like Baclofen, would be fitting sleep aids. Anyone used this med for that reason, or know whether or not it would be fitting?
Thanks,
Psychbot
Posted by ed_uk2010 on March 27, 2011, at 7:10:16
In reply to Baclofen--can it be used for sleep?, posted by psychobot5000 on March 25, 2011, at 12:05:33
> Apparently this is a somewhat sedating med with a reasonably short half-life, that has some similarities, in its mechanism of action, to GHB--yet I can't find any mention of its being used as a hypnotic. Anyone have any insight on this?
>
> If Xyrem is so effective, it would seem to me that other meds that hit the same target (i.e. agonize GABA B receptors), like Baclofen, would be fitting sleep aids. Anyone used this med for that reason, or know whether or not it would be fitting?
>
> Thanks,
> PsychbotI don't think baclofen is too pleasant, it can cause a lot of nausea. It can also cause physical dependence. Might be better off with a standard hypnotic.
Posted by psychobot5000 on March 27, 2011, at 12:04:36
In reply to Re: Baclofen--can it be used for sleep?, posted by ed_uk2010 on March 27, 2011, at 7:10:16
> > Apparently this is a somewhat sedating med with a reasonably short half-life, that has some similarities, in its mechanism of action, to GHB--yet I can't find any mention of its being used as a hypnotic. Anyone have any insight on this?
> >
> > If Xyrem is so effective, it would seem to me that other meds that hit the same target (i.e. agonize GABA B receptors), like Baclofen, would be fitting sleep aids. Anyone used this med for that reason, or know whether or not it would be fitting?
> >
> > Thanks,
> > Psychbot
>
> I don't think baclofen is too pleasant, it can cause a lot of nausea. It can also cause physical dependence. Might be better off with a standard hypnotic.Standard hypnotics don't work for me, thus the exploration of other things.
Posted by ed_uk2010 on March 27, 2011, at 12:30:05
In reply to Re: Baclofen--can it be used for sleep? » ed_uk2010, posted by psychobot5000 on March 27, 2011, at 12:04:36
> > > Apparently this is a somewhat sedating med with a reasonably short half-life, that has some similarities, in its mechanism of action, to GHB--yet I can't find any mention of its being used as a hypnotic. Anyone have any insight on this?
> > >
> > > If Xyrem is so effective, it would seem to me that other meds that hit the same target (i.e. agonize GABA B receptors), like Baclofen, would be fitting sleep aids. Anyone used this med for that reason, or know whether or not it would be fitting?
> > >
> > > Thanks,
> > > Psychbot
> >
> > I don't think baclofen is too pleasant, it can cause a lot of nausea. It can also cause physical dependence. Might be better off with a standard hypnotic.
>
> Standard hypnotics don't work for me, thus the exploration of other things.
>I suppose it might be worth a try, but I wouldn't expect too much. Also bear in mind that baclofen can cause psychiatric adverse reactions.
Posted by psychobot5000 on March 27, 2011, at 13:26:43
In reply to Re: Baclofen--can it be used for sleep?, posted by ed_uk2010 on March 27, 2011, at 12:30:05
> > > > Apparently this is a somewhat sedating med with a reasonably short half-life, that has some similarities, in its mechanism of action, to GHB--yet I can't find any mention of its being used as a hypnotic. Anyone have any insight on this?
> > > >
> > > > If Xyrem is so effective, it would seem to me that other meds that hit the same target (i.e. agonize GABA B receptors), like Baclofen, would be fitting sleep aids. Anyone used this med for that reason, or know whether or not it would be fitting?
> > > >
> > > > Thanks,
> > > > Psychbot
> > >
> > > I don't think baclofen is too pleasant, it can cause a lot of nausea. It can also cause physical dependence. Might be better off with a standard hypnotic.
> >
> > Standard hypnotics don't work for me, thus the exploration of other things.
> >
>
> I suppose it might be worth a try, but I wouldn't expect too much. Also bear in mind that baclofen can cause psychiatric adverse reactions.Ah....these are details I was wondering about--it's often hard to tell from a drug sheet how burdensome the side-effects are likely to be. Thanks, Ed. I appreciate it. Maybe I'll look elsewhere.
Psychbot.
Posted by desolationrower on March 30, 2011, at 11:47:18
In reply to Re: Baclofen--can it be used for sleep?, posted by ed_uk2010 on March 27, 2011, at 12:30:05
I haven't taken it myself (thought i do actually have some in my closet i think) but I haven't seen anything that at correct dosages it has significant side effects. Especially since drowsiness is one of the main side effects, it should show up before other problems.
-d/r
This is the end of the thread.
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