![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by ambidexter on August 11, 2010, at 13:46:37
I have been thinking about trying Nardil for generalized social anxiety for a while, and have read a bunch of stuff about it (some of it here -- thank you all for your posts).
This week I finally took the plunge. A couple weeks before taking it, I started exercising 5x/wk and did Phase I of the South Beach diet. I'm hoping that I will be able to continue exercising and eating low carb, and that this will translate into less weight gain.
In general, I'm trying to do what I can to minimize side effects. So as of the moment, I'm:
-exercising
-on Phase II of South Beach
-eating a bowl of high fiber cereal daily
-drinking green tea in the morning
-taking fish oil capsules
-gonna add a vitamin B supplementAll of which I have read are good things to do, for various reasons?
What do you guys think? What other stuff should I be doing or not doing?
Do you think the timing of medication matters, or the pace at which you increase the dose?
Thanks again to all of you and to Dr. Bob for the tons of information that I have already gotten from this forum. Any additional info is icing on the cake (oops, I mean, sugar-free dressing on the high protein salad) :-)
Posted by angels78 on August 11, 2010, at 13:53:00
In reply to Nardil tips, posted by ambidexter on August 11, 2010, at 13:46:37
Add B6. What dose are you going to be on? Remember higher dosage more side effects. The 1st month is the worst, after that, medicine helps. Try getting a sleep medicine prescribed because you won't sleep w/out one. Don't eat fast food, excercise. Carbs and sugar = stay away from. Check your BP couple times a week just to be safe. Be aware of your body. and most of all
FOLLOW THE MAOI DIET and you'll be good :)
Posted by ambidexter on August 11, 2010, at 18:04:34
In reply to Re: Nardil tips » ambidexter, posted by angels78 on August 11, 2010, at 13:53:00
Thanks, Angel.
Posted by benzo85 on August 12, 2010, at 21:01:37
In reply to Re: Nardil tips, posted by ambidexter on August 11, 2010, at 18:04:34
Just be cognizant that you will WANT to eat and eat and eat those sweets, carbs, anything.
The cravings are Powerful. I found they went away after a few months. But when they're there, just keep fighting them. Drink alot of water. High fiber good.I like to take my whole dosage at night.
Take vits(b6) in morning.
Posted by Ron Hill on August 15, 2010, at 1:56:00
In reply to Nardil tips, posted by ambidexter on August 11, 2010, at 13:46:37
Ambidexter,
I commend you for getting out front of the Nardil side effects. Good for you!
Have you read the Prescribing Information document by Pfizer?
http://www.pfizer.com/files/products/uspi_nardil.pdf
Also, please note that there is a window for the amount of B6 to use:
http://wapedia.mobi/en/Phenelzine
In particular, pay special attention to the following excerpt:
"Phenelzine has also been linked to vitamin B6 deficiency. It reacts with vitamin B6 via an unknown enzyme to form a biologically inert metabolite. Both phenelzine and vitamin B6 are rendered inactive upon this reaction occurring. For this reason, it is recommended to supplement with vitamin B6 while taking phenelzine. High doses of vitamin B6 may significantly lower phenelzine levels and subsequently inhibit its therapeutic benefits, however, and thus, excess quantities of vitamin B6 should be avoided. It may be advisable to dose them separately during opposite intervals of the day (e.g., take one, then take the other 12 hours later) to avoid interaction as much as possible."
Ambidexter, I prefer to take sublingual P-5-P which is the endogenous form of B6.
-- Ron
--------------------------
> I have been thinking about trying Nardil for generalized social anxiety for a while, and have read a bunch of stuff about it (some of it here -- thank you all for your posts).
>
> This week I finally took the plunge. A couple weeks before taking it, I started exercising 5x/wk and did Phase I of the South Beach diet. I'm hoping that I will be able to continue exercising and eating low carb, and that this will translate into less weight gain.
>
> In general, I'm trying to do what I can to minimize side effects. So as of the moment, I'm:
> -exercising
> -on Phase II of South Beach
> -eating a bowl of high fiber cereal daily
> -drinking green tea in the morning
> -taking fish oil capsules
> -gonna add a vitamin B supplement
>
> All of which I have read are good things to do, for various reasons?
>
> What do you guys think? What other stuff should I be doing or not doing?
>
> Do you think the timing of medication matters, or the pace at which you increase the dose?
>
> Thanks again to all of you and to Dr. Bob for the tons of information that I have already gotten from this forum. Any additional info is icing on the cake (oops, I mean, sugar-free dressing on the high protein salad) :-)
Posted by angels78 on August 15, 2010, at 2:12:06
In reply to Re: Nardil tips » ambidexter, posted by Ron Hill on August 15, 2010, at 1:56:00
Ron, excellent post. Thank you.
I have a question for you if you dont mind about the B6. I read the article and I'm a little confused. Now, if B6 is NOT taken, does it effect the theurpatic effect of the drug? Or if taken at a correct dose, help with the therupatic effect of the drug? I also read if taken too much, it can also effect the drug? Can you shed some light into what is an amount to take of b6, and reasons why you should while taking Nardil.
Posted by Ron Hill on August 16, 2010, at 19:10:23
In reply to Re: Nardil tips » Ron Hill, posted by angels78 on August 15, 2010, at 2:12:06
> I have a question for you if you dont mind about the B6. I read the article and I'm a little confused. Now, if B6 is NOT taken, does it effect the theurpatic effect of the drug?
Not to my knowledge. The issue is that the patient will become deficient in B6 which causes a plethora of problems.
> Or if taken at a correct dose, help with the therupatic effect of the drug?
If B6 is taken at the correct dosage (i.e.; not too much B6) then the effectiveness of your Nardil dosage will not be degraded (i.e.; reduced).
> I also read if taken too much, it can also effect the drug?
Yes! This is the issue. High levels of B6 reduce the level of Nardil. AND, Nardil destroys B6. Therefore, there is a "window" regarding the amount of B6 to take as a supplement.
> Can you shed some light into what is an amount to take of b6,
This is a very difficult question to answer. It probably varies from person-to-person. The best way is to get a blood test.
Print a copy of the article that I routed you to, and show your p-doc. If your p-doc blows it off, then get back to me via Babble-mail. If you are unfamiliar with Babble-mail, there are instructions on this site. I always leave my Babble-mail turned on.
> and reasons why you should while taking Nardil.
Because Nardil destroys B6.
As for me, I take 12.5 mg/day of sublingual P-5-P, the endogenous form of B6.
-- Ron
dx: Bipolar II with ultra rapid cycling, and mild OCPD600 mg/day oxcarbazepine (Trileptal)
200 mg/day lamotrigine (Lamictal)
500 mg/day Keppra (levetiracetam)
90 mg/day Nardil (phenelzine)
25 mg/day Valdoxan (agomelatine)
3.75 mg/day Deplin (taken with 2500 mcg/day of sublingual methyl B-12, and 12.5mg/day of sublingual P-5-P)45 ml of Carlsons Bottled Fish Oil
100 mg/day phosphatidylserene
Centrum Chewable Multi-vitamins; Only 100% of all the usual vitamins; NO VANADIUM!!
2000 IU Vitamin E
850 mg/day of Mg 212% of RDA (as 5 grams of Mg Malate).
Dark therapy via LowBlueLight glasses (When I remember)
Whats next to add?:300 mg/day of Lithobid
CoQ10
NAC, + 8 to 10 glasses of water, + Acetyl-L-Carnitine, + Alpha-Lipoic Acid, + Vitamin C
GTF Chromium
Cromium Picolinate
Cinnamon
Posted by ambidexter on August 16, 2010, at 19:39:52
In reply to Re: Nardil tips » angels78, posted by Ron Hill on August 16, 2010, at 19:10:23
Thanks everyone, especially Ron for your detailed advice. That's interesting about the B6.
Posted by Ron Hill on August 16, 2010, at 19:49:35
In reply to Re: Nardil tips, posted by ambidexter on August 16, 2010, at 19:39:52
> Thanks everyone, especially Ron for your detailed advice. That's interesting about the B6.
Ambidexter,
Thanks for saying thanks. It feels good.
Be well my friend.
-- Ron
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.