![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by TriedEveryMedication on August 3, 2010, at 0:15:24
Did you notice any depression and/or lack of motivation when first starting the memantine?
If so, did it pass eventually?Thanks.
Posted by g_g_g_unit on August 3, 2010, at 9:54:03
In reply to Memantine users -did you get depression initially?, posted by TriedEveryMedication on August 3, 2010, at 0:15:24
how much are you currently taking? i found memantine to have a potent-yet-ultimately-impractical stimulating effect for the first few days i spent at 5mg - by which i mean, i became so caught up in my own animated streams of thought that it became impossible to focus on anything else. thereafter i found that the effects indeed fluctuated and there were days where i felt particularly depressed and emotionally reactive. i ultimately gave up after reaching 20mg, but think i may have potentially done better at a lower dose.
remember that due to its long (72 hour) half-life, you need to give each dose at least a week to reach stable blood concentrations. from what i can gather, therapeutically beneficial doses range from between 10 and 20mg in the case of ADD, so it might be a good idea to give each dose some time before determining whether it's necessary to move up. for what it's worth, most of the benefits seem to be with respect to focus/attention. i've never heard of it negatively impacting motivation, but i don't know if it will do much to improve it.
Posted by TriedEveryMedication on August 3, 2010, at 19:29:35
In reply to Re: Memantine users -did you get depression initially?, posted by g_g_g_unit on August 3, 2010, at 9:54:03
Posted by TriedEveryMedication on August 10, 2010, at 2:11:19
In reply to Memantine users -did you get depression initially?, posted by TriedEveryMedication on August 3, 2010, at 0:15:24
So if I take this stuff as directed, 5mg in the morning and 5mg in the afternoon, I can't sleep at all
5mg in the morning alone seems to be ok.Can you take 10mg in the morning?
Posted by g_g_g_unit on August 11, 2010, at 4:44:58
In reply to Re: Memantine --- massive insomnia at BID, posted by TriedEveryMedication on August 10, 2010, at 2:11:19
> So if I take this stuff as directed, 5mg in the morning and 5mg in the afternoon, I can't sleep at all
>
>
> 5mg in the morning alone seems to be ok.
>
> Can you take 10mg in the morning?Given the half-life, I would assume it's fine to take 10mg at once. I suffer from insomnia anyway, but don't recall it making my sleep any *worse*. I've read studies where it enhanced sleep quality . . .
One dude (a med student) posting on the ADD forums has said that, given the drug's ridiculous half-life, it's vital that you dose at the same time each day, and try to maintain a stable sleep/wake schedule.
Posted by ed_uk2010 on August 11, 2010, at 14:31:22
In reply to Re: Memantine --- massive insomnia at BID, posted by TriedEveryMedication on August 10, 2010, at 2:11:19
>if I take this stuff as directed, 5mg in the morning and 5mg in the afternoon, I can't sleep at all...
In the UK, memantine is given once daily (at the same time each day).
Posted by TriedEveryMedication on August 14, 2010, at 7:37:09
In reply to Re: Memantine --- massive insomnia at BID, posted by ed_uk2010 on August 11, 2010, at 14:31:22
hi ed,
Thanks for that bit of info. I'm going to try QD dosing now.
Thanks
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.