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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by linkadge on July 14, 2010, at 17:02:55
Could citalopram cause less apathy than escitalopram?
Doesn't the other enatomer in citalopram enhance serotonin reuptake. If this is the case the might counteract some of the apathy ?
Linkadge
Posted by TenMan on July 14, 2010, at 23:33:56
In reply to citalopram vs. escitalopram, posted by linkadge on July 14, 2010, at 17:02:55
I was under the impression that the R-enantiomer was detrimental to the effect by impeding serotonin reuptake and being anticholinergic?
Posted by SLS on July 15, 2010, at 0:12:56
In reply to Re: citalopram vs. escitalopram, posted by TenMan on July 14, 2010, at 23:33:56
> I was under the impression that the R-enantiomer was detrimental to the effect by impeding serotonin reuptake and being anticholinergic?
I think the R-enantiomer occupies the serotonin transporter without inhibiting its function. It blocks the S-enantiomer from doing its work. Still, I have seen a few people on PB report responding better to citalopram than escitalopram.
- Scott
Posted by ed_uk2010 on July 16, 2010, at 16:26:57
In reply to citalopram vs. escitalopram, posted by linkadge on July 14, 2010, at 17:02:55
> Could citalopram cause less apathy than escitalopram?
>
> Doesn't the other enatomer in citalopram enhance serotonin reuptake. If this is the case the might counteract some of the apathy ?
>
> LinkadgeI've taken them both but I didn't notice a difference.
Posted by bearfan on July 24, 2010, at 22:08:10
In reply to citalopram vs. escitalopram, posted by linkadge on July 14, 2010, at 17:02:55
I noticed that the start-up effects were significantly lower with escitalopram (lexapro)
Posted by MaybeSo on July 28, 2010, at 8:49:47
In reply to citalopram vs. escitalopram, posted by linkadge on July 14, 2010, at 17:02:55
When I switched, for cost reasons, from escitalopram to citalopram, I had to add Wellbutrin to give me a kick of agency.
When I went back to citalopram, I had to stop the bupropion because of overstimulation (into anxiety).
This is the end of the thread.
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