Shown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Economist on July 1, 2010, at 14:39:28
Sorry if this topic is not allowed here. I just wanted to know if anyone here has first hand experience with cocaine while on an SSRI.
What about cocaine while on an antipsychotic (Abilify)?
Please no brow-beating about how you shouldn't do drugs -- just want the facts regarding this combination! :)
Posted by Christ_empowered on July 1, 2010, at 15:41:36
In reply to Cocaine and other street drugs while on Prozac., posted by Economist on July 1, 2010, at 14:39:28
I would think with Prozac it would 1) dull the high a little bit; 2) help with depression for a bit, if that's the problem and 3) have a slightly less severe crash. However, you would have to worry about Serotonin Syndrome, although I don't think that's too common.
Abilify is an antipsychotic, so I'd expect it to dull the high also. You might get mild muscle jerks and what not if you do enough b/c of the antipsychotic floating around in your system.
Posted by linkadge on July 1, 2010, at 17:49:28
In reply to Re: Cocaine and other street drugs while on Prozac., posted by Christ_empowered on July 1, 2010, at 15:41:36
Yeah, I've heard that SSRI's can supress the cocaine high. They seem to do the same for MDMA.
Linkadge
Posted by Phillipa on July 1, 2010, at 18:06:52
In reply to Re: Cocaine and other street drugs while on Prozac., posted by linkadge on July 1, 2010, at 17:49:28
There was or maybe still is a substance board on babble. Not sure if gone. Phillipa
Posted by rjlockhart04-08 on July 1, 2010, at 19:25:28
In reply to Cocaine and other street drugs while on Prozac., posted by Economist on July 1, 2010, at 14:39:28
Abilify would levelize the mood, so cocaine would not be as euphoric as it could. Abilify blocks dopamine in some areas, but still you would get some stimulantion from cocaine. Now if you took Haldol...that would cancel alot of the euphoria out.
thats all
M
Posted by Conundrum on July 2, 2010, at 0:57:26
In reply to Cocaine and other street drugs while on Prozac., posted by Economist on July 1, 2010, at 14:39:28
I think the is a real threat of serotonin syndrome with that combo since both drugs potently block serotonin reuptake. If you're gonna do something like that try ritalin instead.
Posted by West on July 6, 2010, at 19:06:39
In reply to Re: Cocaine and other street drugs while on Prozac. » Economist, posted by Conundrum on July 2, 2010, at 0:57:26
I remember the days when I could get away with doing half a gram of coke on fluoxetine 40mg, drink 4 pints and 4 mixers and still be relatively ok the next day. In fact i don't think I would have gotten involved in cocaine if i wasn't taking fluoxetine, it freed up dopamine and allowed me to feel alive for once.
There's very little to suggest the combination is capable of producing serotonin syndrome, nor does it carry any additional dangers above those already present. Mice on the combination exhibited increased locomotor activity.
Data suggests taking it lowers the ability to experience pleasure (google DeltaFosB and cocaine).
I remember having cravings for up to a year after my last line. I was grateful when the last time I took it I became so depressed the following day, it lost its appeal forever.
Posted by linkadge on July 7, 2010, at 16:00:40
In reply to Re: Cocaine and other street drugs while on Prozac., posted by West on July 6, 2010, at 19:06:39
>Data suggests taking it lowers the ability to >experience pleasure (google DeltaFosB and >cocaine).
Doesn't taking cocaine increase DeltaFosB ?
Linkadge
This is the end of the thread.
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