Psycho-Babble Medication Thread 946655

Shown: posts 1 to 6 of 6. This is the beginning of the thread.

 

Parnate and Lithium

Posted by kirbyw on May 7, 2010, at 11:56:14

I have used Parnate successfully for over 20 years. But after by pass surgery in 08 I have had the problem of parnate interaction with the beta blocker (heart med) that I use as a by pass patient.
Without the beta blocker (Lopressor) my heart rate gets too high, like around 100. But with the Parnate my blood pressure gets quite low and exercise (which I am supposed to be doing) is unpleasant and difficult.

In the mean time two expert docs suggested that I try Lithium as I may be atypical bi-polar. I have been on Lithium for over a month and my Lithium level is now .9 which is in the therapeutic range. But I seem to be feeling worse emotionally, as if the Lithium and the Parnate are not working out well together. I have only been at the therapeutic level of Lithium for about 2 weeks, so I don't know if it is too soon to make a judgment.

I would really like to be on a higher dose of Parnate (30 mg is my dose) but the higher dose interferes even more with the Beta Blocker. Its really too bad.
Along with the bypass surgery have come other problems such as unemployment etc, so this is not good.
Anyway any advice is welcome. Especially about Lithium and Parnate, and if someone can miraculously make a suggest for the Parnate/Lopressor interaction.
rick in costa Rica

 

Re: Parnate and Lithium ยป kirbyw

Posted by Phillipa on May 7, 2010, at 13:02:53

In reply to Parnate and Lithium, posted by kirbyw on May 7, 2010, at 11:56:14

Ahh Rick isn't it horrible that so many other classes of meds can mess up a good thing? I can't answer your question but wanted to let you know I care. Phillipa

 

Re: Parnate and Lithium

Posted by ed_uk2010 on May 7, 2010, at 13:42:05

In reply to Parnate and Lithium, posted by kirbyw on May 7, 2010, at 11:56:14

I think it would be useful to discuss with your cardiologist whether you could try a different medication to control your heart rate instead of metoprolol (Lopressor). Verapamil might be a possibilty.

 

Re: Parnate and Lithium

Posted by desolationrower on May 7, 2010, at 19:50:35

In reply to Re: Parnate and Lithium, posted by ed_uk2010 on May 7, 2010, at 13:42:05

other treatment for heart rate is probably easiest.

why does the gastro surgery cause high heart rate? i think andrenoceptors are involved in gi motility too.


if the combination was ok except for low blood pressure, you might just add something that has a pressor effect. if you added a tca, the beta blocker might just push the effect onto the alpha receptors and cause BP increase (which is why bblockers are bad if you have high BP from say cocaine) but probably your doctor will say 'hypertensive crisis risk'. though, the tca prevents risk of tyramine-induced hypertensive crisis.

-d/r

 

Re: Parnate and Lithium

Posted by kirbyw on May 8, 2010, at 0:56:37

In reply to Re: Parnate and Lithium, posted by desolationrower on May 7, 2010, at 19:50:35

> other treatment for heart rate is probably easiest.
>
> why does the gastro surgery cause high heart rate? i think andrenoceptors are involved in gi motility too.
>
>
> if the combination was ok except for low blood pressure, you might just add something that has a pressor effect. if you added a tca, the beta blocker might just push the effect onto the alpha receptors and cause BP increase (which is why bblockers are bad if you have high BP from say cocaine) but probably your doctor will say 'hypertensive crisis risk'. though, the tca prevents risk of tyramine-induced hypertensive crisis.
>
> -d/r

It wasn't gastric by pass. It was a double coronary by-pass. also known as open heart surgery. Thanks for your comments.
Rick

 

Re: Parnate and Lithium

Posted by desolationrower on May 8, 2010, at 2:11:00

In reply to Re: Parnate and Lithium, posted by kirbyw on May 8, 2010, at 0:56:37

> > other treatment for heart rate is probably easiest.
> >
> > why does the gastro surgery cause high heart rate? i think andrenoceptors are involved in gi motility too.
> >
> >
> > if the combination was ok except for low blood pressure, you might just add something that has a pressor effect. if you added a tca, the beta blocker might just push the effect onto the alpha receptors and cause BP increase (which is why bblockers are bad if you have high BP from say cocaine) but probably your doctor will say 'hypertensive crisis risk'. though, the tca prevents risk of tyramine-induced hypertensive crisis.
> >
> > -d/r
>
> It wasn't gastric by pass. It was a double coronary by-pass. also known as open heart surgery. Thanks for your comments.
> Rick

oh, oops. i guess it doesn't really affect what else i said

-d/r


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