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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 25 of 26. This is the beginning of the thread.
Posted by tensor on May 6, 2010, at 12:56:46
My combo with Remeron and clomipramine is working. I finally have energy, motivation and interest to do something. I'm feeling better now than I have done in years. I'm still tuning the clomipramine dosage, but currently I'm taking 150mg with 30mg Remeron. The only troublesome side effects are anorgasmia and dry mouth.
/Mattias
Posted by Phillipa on May 6, 2010, at 13:15:50
In reply to clomipramine/Remeron combo, posted by tensor on May 6, 2010, at 12:56:46
Tensor you feel great now. Give the other time and please enjoy feeling well that's wonderful. Seems like quite a few are doing well on clomipramine. Love Phillipa
Posted by bulldog2 on May 6, 2010, at 13:21:34
In reply to clomipramine/Remeron combo, posted by tensor on May 6, 2010, at 12:56:46
> My combo with Remeron and clomipramine is working. I finally have energy, motivation and interest to do something. I'm feeling better now than I have done in years. I'm still tuning the clomipramine dosage, but currently I'm taking 150mg with 30mg Remeron. The only troublesome side effects are anorgasmia and dry mouth.
>
> /MattiasTry dostinex, or miraprex or requip
Dopamine agonists often work
Posted by SLS on May 6, 2010, at 15:14:41
In reply to clomipramine/Remeron combo, posted by tensor on May 6, 2010, at 12:56:46
> My combo with Remeron and clomipramine is working.
That's great. You deserve it.
- Scott
Posted by floatingbridge on May 6, 2010, at 18:32:28
In reply to clomipramine/Remeron combo, posted by tensor on May 6, 2010, at 12:56:46
Yay!
May I ask a question or two?
Do you take the remeron at night, and if so, is it reasonably 'gone' by morning?
Does the remeron work around the clock in relieving anxiety (that is if you had it)?
Good for you! :-)
Posted by Bob on May 6, 2010, at 22:00:50
In reply to clomipramine/Remeron combo, posted by tensor on May 6, 2010, at 12:56:46
> My combo with Remeron and clomipramine is working. I finally have energy, motivation and interest to do something. I'm feeling better now than I have done in years. I'm still tuning the clomipramine dosage, but currently I'm taking 150mg with 30mg Remeron. The only troublesome side effects are anorgasmia and dry mouth.
>
> /MattiasThat's an interesting combo, and one I don't think I've ever heard suggested before. How did you come to the decision to try it? Was is suggested by your psychiatrist?
Bob
Posted by Bob on May 6, 2010, at 22:08:13
In reply to Re: clomipramine/Remeron combo » tensor, posted by Phillipa on May 6, 2010, at 13:15:50
> Tensor you feel great now. Give the other time and please enjoy feeling well that's wonderful. Seems like quite a few are doing well on clomipramine. Love Phillipa
Unbelievable how things come full circle. Clomipramine was the second drug I tried back in the early nineties. If my memory serves me, the drug caused me massive weight gain, sweating problems, difficulty with urination, and significant anorgasmia. That's just what I can remember though. It did address my problems, at least to a certain extent, but at the time with little exposure to psych drugs I couldn't believe there wasn't something better out there. Now I've gotta wonder whether maybe there really isn't anything better for people like me. I've spent the last 17 or so years experimenting and struggling in vain and have never found anything that worked for more than maybe a month or two - and that was only one or two drugs out of the countless I've tried.I guess everyone's different.
Posted by tensor on May 7, 2010, at 5:24:24
In reply to Re: clomipramine/Remeron combo » tensor, posted by floatingbridge on May 6, 2010, at 18:32:28
> Do you take the remeron at night, and if so, is it reasonably 'gone' by morning?
Yes, I take it at night and I have never had any problems with 'hangover', although it helps me fall asleep.
> Does the remeron work around the clock in relieving anxiety (that is if you had it)?I'm not sure how much Remeron helps with my anxiety, it would not be enough on its own. Clomipramine definitely helps and I also take clonazepam regularly, so it's hard to say.
/Mattias
Posted by tensor on May 7, 2010, at 5:42:34
In reply to Re: clomipramine/Remeron combo » tensor, posted by Bob on May 6, 2010, at 22:00:50
> That's an interesting combo, and one I don't think I've ever heard suggested before. How did you come to the decision to try it? Was is suggested by your psychiatrist?
First of all, clomipramine is probably the most widely used TCA here (Finland), not only for OCD but for depression. I suggested the combo but my sister have taken it for a decade. I tried it a few years ago but I switched to Edronax after a few weeks because I thought I only needed the NRI part.
/Mattias
Posted by tensor on May 7, 2010, at 5:48:51
In reply to Re: clomipramine/Remeron combo, posted by bulldog2 on May 6, 2010, at 13:21:34
> Try dostinex, or miraprex or requip
> Dopamine agonists often workI once suggested DA agonists for my pdoc to use as antidepressants but he was reluctant because he had no experience with them. Have you used them as antidotes for AD induced sexual problems? They seem to have nasty side effects, but I don't know. Is there a DA agonist to prefer over the others?
/Mattias
Posted by tensor on May 7, 2010, at 5:49:53
In reply to Re: clomipramine/Remeron combo » tensor, posted by Phillipa on May 6, 2010, at 13:15:50
Posted by tensor on May 7, 2010, at 5:50:25
In reply to Re: clomipramine/Remeron combo, posted by SLS on May 6, 2010, at 15:14:41
Posted by polarbear206 on May 7, 2010, at 8:02:29
In reply to clomipramine/Remeron combo, posted by tensor on May 6, 2010, at 12:56:46
> My combo with Remeron and clomipramine is working. I finally have energy, motivation and interest to do something. I'm feeling better now than I have done in years. I'm still tuning the clomipramine dosage, but currently I'm taking 150mg with 30mg Remeron. The only troublesome side effects are anorgasmia and dry mouth.
>
> /Mattia
Glad to hear and very happy for you. Knowing that Remeron has minimal sexual side effects, you may be able to up it at some point and cut back on the clomipramine. :)
Posted by ed_uk2010 on May 7, 2010, at 13:33:50
In reply to Re: clomipramine/Remeron combo » bulldog2, posted by tensor on May 7, 2010, at 5:48:51
Hi Mattias,
Excellent news that you're feeling so much better :)
Perhaps you could get some lozenges, mouth gel or a spray for the dry mouth. I don't know what you have in Finland but some of the best brands from the UK are AS Saliva Orthana, Biotene OralBalance and BioXtra.
About the dopamine agonists... I've not heard of anyone who took them for depression or sexual problems who didn't stop taking them after a short while. Problematic side effects seem to be very frequent, including psychiatric reactions. I find this quite worrying.
Posted by bulldog2 on May 7, 2010, at 17:30:01
In reply to Re: clomipramine/Remeron combo » bulldog2, posted by tensor on May 7, 2010, at 5:48:51
> > Try dostinex, or miraprex or requip
> > Dopamine agonists often work
>
> I once suggested DA agonists for my pdoc to use as antidepressants but he was reluctant because he had no experience with them. Have you used them as antidotes for AD induced sexual problems? They seem to have nasty side effects, but I don't know. Is there a DA agonist to prefer over the others?
>
> /MattiasSomeone on nardil recently posted that he used dostinex for nardil induced sexual problems and that it worked well.
Posted by tensor on May 8, 2010, at 4:40:21
In reply to Re: clomipramine/Remeron combo, posted by bulldog2 on May 7, 2010, at 17:30:01
> Someone on nardil recently posted that he used dostinex for nardil induced sexual problems and that it worked well.
Ok, thanks, I'll keep it in mind.
/Mattias
Posted by tensor on May 8, 2010, at 4:53:58
In reply to Re: clomipramine/Remeron combo » tensor, posted by ed_uk2010 on May 7, 2010, at 13:33:50
> Excellent news that you're feeling so much better :)
Thanks :)
> Perhaps you could get some lozenges, mouth gel or a spray for the dry mouth. I don't know what you have in Finland but some of the best brands from the UK are AS Saliva Orthana, Biotene OralBalance and BioXtra.I got a spray (Proxident) from my dentist which works pretty good and lozenges from the pharmacy, both contain malic acid and some other stuff.
> About the dopamine agonists... I've not heard of anyone who took them for depression or sexual problems who didn't stop taking them after a short while. Problematic side effects seem to be very frequent, including psychiatric reactions. I find this quite worrying.
Yeah, I know. I have heard of people starting to hallucinate on them. That would only be of help if you happened to see nude women. Well, jokes aside, I don't know what todo really. Cyproheptadine is not available here, and I wonder how much sildenafil helps with anorgasmia.
Kind regards,
Mattias
Posted by ed_uk2010 on May 8, 2010, at 14:17:42
In reply to Re: clomipramine/Remeron combo » ed_uk2010, posted by tensor on May 8, 2010, at 4:53:58
>I got a spray (Proxident) from my dentist which works pretty good and lozenges from the pharmacy, both contain malic acid and some other stuff.
The problem with malic acid products is that acidic lozenges are believed to damage the tooth enamel. pH-neutral sprays are the best. Some contain fluoride to help protect against decay. Mucin-based sprays are more effective than carboxymethylcellulose sprays. Sugar free chewing gum is often effective and is obviously very inexpensive.
Hope this helps.
Posted by floatingbridge on May 8, 2010, at 22:32:25
In reply to Re: clomipramine/Remeron combo » tensor, posted by ed_uk2010 on May 8, 2010, at 14:17:42
Gum w/ xylitol is actually good for teeth and gums.
Spry is a brand of dental hygiene products available in the states--some for dry mouth-- that utilize xylitol.
Posted by ed_uk2010 on May 9, 2010, at 6:09:07
In reply to Re: clomipramine/Remeron combo » ed_uk2010, posted by floatingbridge on May 8, 2010, at 22:32:25
>Gum w/ xylitol is actually good for teeth and gums.
They use it in some of the sprays and oral gels too.
Posted by conundrum on May 9, 2010, at 21:05:31
In reply to Re: clomipramine/Remeron combo » floatingbridge, posted by ed_uk2010 on May 9, 2010, at 6:09:07
Nice, glad to hear you are doing better. Just goes to show how these drugs can have paradoxical reactions in some people. One might think that combo would be sedative, but it gets you motivated. Cool!
Posted by Meltingpot on May 12, 2010, at 16:58:52
In reply to clomipramine/Remeron combo, posted by tensor on May 6, 2010, at 12:56:46
Hi,
How long did it take for that combo to work?
My psychiatrist has added remeron to seroxat (which already tried twice in the past). I've been on this combination for over six weeks and I really don't think that the remeron is helping much.
The pleasure factor seems to have gone out of my life and has since 2005 and I'm trying to get it back again.
Denise
Posted by tensor on May 14, 2010, at 4:14:26
In reply to Re: clomipramine/Remeron combo, posted by Meltingpot on May 12, 2010, at 16:58:52
> Hi,
>
> How long did it take for that combo to work?
>
> My psychiatrist has added remeron to seroxat (which already tried twice in the past). I've been on this combination for over six weeks and I really don't think that the remeron is helping much.
>
> The pleasure factor seems to have gone out of my life and has since 2005 and I'm trying to get it back again.
>
>
> DeniseHi,
when I reached a dosage of 150mg it took only a few days, so in total 2 weeks. I'm currently on 150mg + 30mg Remeron and it's also great for anxiety, I feel better in several aspects. I think it's important to treat anxiety aggressively because it drains you on energy.
Kind regards,
Mattias
Posted by ed_uk2010 on May 14, 2010, at 14:13:55
In reply to Re: clomipramine/Remeron combo » Meltingpot, posted by tensor on May 14, 2010, at 4:14:26
Hi Mattias,
Are you hoping to return to work soon?
Posted by tensor on May 14, 2010, at 14:48:20
In reply to Re: clomipramine/Remeron combo » tensor, posted by ed_uk2010 on May 14, 2010, at 14:13:55
> Hi Mattias,
>
> Are you hoping to return to work soon?Hi!
I hope I can return in a few months, perhaps September. I have plenty of stuff to catch up with at home and I need to see if my mood improvement will last a little longer than a couple of months. I'm also working on reducing stressors, I have a habit of always trying to achieve perfection, which is something I have had problems with. I.e. if I can't do it 100% perfect, I won't do it at all or give up.
Kind regards,
Mattias
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