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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by Phillipa on November 19, 2009, at 18:34:08
Simple to read study from psych central seems SSRI's and TCA's Do or may contribute to osteoporosis. Phillipa
http://psychcentral.com/news/2007/06/26/common-antidepressants-risk-osteoporosis/918.html
Posted by bleauberry on November 20, 2009, at 4:56:28
In reply to SSRI's Do Contribute To Osteoporosis per Psych Cen, posted by Phillipa on November 19, 2009, at 18:34:08
All these studies are full of words such as "may", "could", "possibly". That has to be considered.
Whatever the case, I think depression is a much worse scenario than osteoporosis. I mean, what good are healthy bones if one has no sparkle to be alive?
Posted by glydin00 on November 20, 2009, at 8:52:32
In reply to SSRI's Do Contribute To Osteoporosis per Psych Cen, posted by Phillipa on November 19, 2009, at 18:34:08
FYI... other POTENTIAL risk factors:
Your sex. Fractures from osteoporosis are about twice as common in women as they are in men. That's because women start out with lower bone mass and tend to live longer. They also experience a sudden drop in estrogen at menopause that accelerates bone loss. Slender, small-framed women are particularly at risk. Men who have low levels of the male hormone testosterone also are at increased risk. The risk of osteoporosis in men is greatest from age 75 on.
Age. The older you get, the higher your risk of osteoporosis. Your bones become weaker as you age.
Race. You're at greatest risk of osteoporosis if you're white or of Southeast Asian descent. Black and Hispanic men and women have a lower, but still significant, risk.
Family history. Osteoporosis runs in families. For that reason, having a parent or sibling with osteoporosis puts you at greater risk, especially if you also have a family history of fractures.
Frame size. Men and women who are exceptionally thin or have small body frames tend to have higher risk because they may have less bone mass to draw from as they age.
Tobacco use. The exact role tobacco plays in osteoporosis isn't clearly understood, but researchers do know that tobacco use contributes to weak bones.
Lifetime exposure to estrogen. The greater a woman's lifetime exposure to estrogen, the lower her risk of osteoporosis. For example, you have a lower risk if you have a late menopause or you began menstruating at an earlier than average age. But your risk of osteoporosis is increased if your lifetime exposure to estrogen has been deficient, such as from infrequent menstrual periods or menopause before age 45.
Eating disorders. Women and men with anorexia nervosa or bulimia are at higher risk of lower bone density in their lower backs and hips.
Corticosteroid medications. Long-term use of corticosteroid medications, such as prednisone, cortisone, prednisolone and dexamethasone, is damaging to bone. These medications are common treatments for chronic conditions, such as asthma, rheumatoid arthritis and psoriasis. If you need to take a steroid medication for long periods, your doctor should monitor your bone density and recommend other drugs to help prevent bone loss.
Thyroid hormone. Too much thyroid hormone also can cause bone loss. This can occur either because your thyroid is overactive (hyperthyroidism) or because you take excess amounts of thyroid hormone medication to treat an underactive thyroid (hypothyroidism).
Selective serotonin reuptake inhibitors (SSRIs). Research published in 2007 showed lower bone mineral density among both men and women currently using SSRIs compared with study participants not taking these antidepressants. However, these results don't necessarily mean that SSRIs cause bone loss or osteoporosis. More research is needed to fully understand the association between SSRI use and low bone density. Evidence does not currently indicate that you should stop using SSRIs because of concerns about bone loss.
Other medications. Long-term use of the blood-thinning medication heparin, the cancer treatment drug methotrexate, some anti-seizure medications, diuretics and aluminum-containing antacids also can cause bone loss.
Breast cancer. Postmenopausal women who have had breast cancer are at increased risk of osteoporosis, especially if they were treated with chemotherapy or aromatase inhibitors such as anastrozole and letrozole, which suppress estrogen. This isn't true for women treated with tamoxifen, which may reduce the risk of fractures.
Low calcium intake. A lifelong lack of calcium plays a major role in the development of osteoporosis. Low calcium intake contributes to poor bone density, early bone loss and an increased risk of fractures.
Medical conditions and procedures that decrease calcium absorption. Stomach surgery (gastrectomy) can affect your body's ability to absorb calcium. So can conditions such as Crohn's disease, celiac disease, vitamin D deficiency, anorexia nervosa and Cushing's disease a rare disorder in which your adrenal glands produce excessive corticosteroid hormones.
Sedentary lifestyle. Bone health begins in childhood. Children who are physically active and consume adequate amounts of calcium-containing foods have the greatest bone density. Any weight-bearing exercise is beneficial, but jumping and hopping seem particularly helpful for creating healthy bones. Exercise throughout life is important, but you can increase your bone density at any age.
Excess soda consumption. The link between osteoporosis and caffeinated sodas isn't clear, but caffeine may interfere with calcium absorption and its diuretic effect may increase mineral loss. In addition, the phosphoric acid in soda may contribute to bone loss by changing the acid balance in your blood. If you do drink caffeinated soda, be sure to get adequate calcium and vitamin D from other sources in your diet or from supplements.
Chronic alcoholism. For men, alcoholism is one of the leading risk factors for osteoporosis. Excess consumption of alcohol reduces bone formation and interferes with the body's ability to absorb calcium.
Depression. People who experience serious depression have increased rates of bone loss.
Posted by Phillipa on November 20, 2009, at 12:13:14
In reply to Re: SSRI's Do Contribute To Osteoporosis per Psych Cen, posted by glydin00 on November 20, 2009, at 8:52:32
Seems that the bioidenticals are the meds of choice then as it increases the estrogen again. A friend on facebook sold evista another Serm like tamoxifem and said that is what she would take in a heartbeat. Only negative with the evista is blood clots from my research but the osteoclasts don't rebuild bone they break it down and seems the osteoblasts don't build new bone just the dead bone from the osteoclasts appears to seem on a Dexa Scan that the bone is denser. So that eliminates fosamax, boniva, actonel.
D3 was tested adequate middle of normal but take it anyway with the calcium magnesium have taken since 20's so that front is covered. They say now vita K is also a bone builder. So that's in my calcium also. Strangly I feel that the synthroid isn't needed anymore. Also was a Tom boy so played baseball, always hiking, swim team, walking when kids little, running for years, lifting weights, ran til 59 when I tripped and fell and fractured arm. So It seems that excercise didn't do it. And all the high level aerobic dance I choreographed and taught and trained the instructors didn't help. Pain to me is worse than any dysthymia I may have. Always the anxiety which seems also to not need the benzos down to lmg of xanax and 7.5 valium with the 50 luvox which I know increases the blood levels of benzos. I'm thinking of just cold turkeying the benzos as I sleep to late. Look at the time I'm on the computer. Okay up til three but no excuse. Still ride the bike nightly in the dark. I still feel since the lymes and thyroid same time went that is when most of problems started. I'm really glad to see posting on here and am glad that some are posting. Blue still need to reply to you. Thanks for answering. My appointment with the bone doc Dec. Then since still using half the dose of bioidenticals I will decide whether to get back to full dose on them. Oh my neighbor who had breast cancer only 50 now took her tamoxifen and still has osteo and is on I think actonel as boniva did nothing for it. Bone Dexa was bad. So many searches out there on this topic. Amazing. Love Phillipa ps google the newest hotest supplement out there for bone growth wwwbonegrowth.com. It's a scam in my opinion
Posted by Phillipa on November 20, 2009, at 13:19:32
In reply to Re: SSRI's Do Contribute To Osteoporosis per Psych Cen » glydin00, posted by Phillipa on November 20, 2009, at 12:13:14
Another approach all lead the same way. Phillipa
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Posted by glydin00 on November 20, 2009, at 16:29:17
In reply to Re: SSRI's Do Contribute To Osteoporosis per Psych Cen » glydin00, posted by Phillipa on November 20, 2009, at 12:13:14
I posted mainly to point out other factors involved and in fairness of the info, on other agents (meds specifically) which MAY contribute to loss of bone density. I believe I read a post which someone posted their SSRI use gave them osteoporosis. (Smile)
To date, I know of no recommendations from any reputable sources (well, reputable IMO) on the drugs nor on their classes listed in my post above which advises the ditching of any of those meds due to any huge risk of worsening the condition. The unchangeable risk factors of age and gender appear to me to be the paramount ones if one is looking at what are the true "reasons".
In fact the 2007 study, which is cited, clearly states more information is needed and clearly states the study's potential to be not a true reflection of the actual risk.
I understand your concern for your personal health but do you really believe AD's and developing or worsening osteoporosis have a true connection worth discontinuing their use?
Posted by Phillipa on November 20, 2009, at 19:20:01
In reply to Re: » Phillipa, posted by glydin00 on November 20, 2009, at 16:29:17
Maybe not for all some do well on them. Since mine doesn't I'm seriously thinking of cutting down and off again. The only thing that ever worked for me were benzos til the thyroid. And that runs in the family. So for me maybe. Love Phillipa
Posted by floatingbridge on November 21, 2009, at 23:12:50
In reply to Re: SSRI's Do Contribute To Osteoporosis per Psych Cen » glydin00, posted by Phillipa on November 20, 2009, at 12:13:14
Phillipa,
Are you going to continue or increase bioidenticals?
fb
Posted by Phillipa on November 22, 2009, at 19:07:13
In reply to Re: SSRI's Do Contribute To Osteoporosis per Psych » Phillipa, posted by floatingbridge on November 21, 2009, at 23:12:50
I just don't know. My anxiety is acting strange? Plus my oldest won't let us stay at her house in Florida at Christmas Time while she and her husband are in Italy. See ebay is slow then. Love Phillipa
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