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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Meltingpot on September 6, 2009, at 11:38:04
Hi,
Can somebody explain to me why there seem to be a number of trials for depression listed on the http://www.clinicaltrials.gov site which have a status of complete and yet don't give any results. It's really frustrating.
Does anyone know where the results are published?
Thanks.....Denise
Posted by Phillipa on September 6, 2009, at 12:46:52
In reply to Clinical trials.gov - Completed trials, posted by Meltingpot on September 6, 2009, at 11:38:04
Hi Denise miss you. I think a lot of babblers are away for the weekend it's a holiday weekend here. But maybe some will check in how you doing? Love Phillipa
Posted by yxibow on September 6, 2009, at 21:36:30
In reply to Clinical trials.gov - Completed trials, posted by Meltingpot on September 6, 2009, at 11:38:04
> Hi,
>
> Can somebody explain to me why there seem to be a number of trials for depression listed on the http://www.clinicaltrials.gov site which have a status of complete and yet don't give any results. It's really frustrating.
>
> Does anyone know where the results are published?
I doubt you will see where results for clinical trials are published for a while. If they show efficacy they will appear in a journal probably and a new Phase (I,II,II) trial will start.Otherwise it will probably come out eventually that the initial Phase trial did not work, caused substantial side effects, or showed no efficacy.
I don't think its instant.
-- tidings
Posted by meltingpot on September 7, 2009, at 3:34:06
In reply to Re: Clinical trials.gov - Completed trials » Meltingpot, posted by Phillipa on September 6, 2009, at 12:46:52
Hi Philipa,
Thanks. How are things going with you?
Denise
Posted by meltingpot on September 7, 2009, at 3:35:53
In reply to Re: Clinical trials.gov - Completed trials » Meltingpot, posted by yxibow on September 6, 2009, at 21:36:30
Hi,
Thanks for your response. If that is the case then I cannot understand why they put trials on there to start with if they don't enter the results. There is a section on the Clinical trials site for them to put the results but they don't seem to bother.
Denise
Posted by yxibow on September 7, 2009, at 4:10:07
In reply to Re: Clinical trials.gov - to yxibow, posted by meltingpot on September 7, 2009, at 3:35:53
> Hi,
>
> Thanks for your response. If that is the case then I cannot understand why they put trials on there to start with if they don't enter the results. There is a section on the Clinical trials site for them to put the results but they don't seem to bother.
>
> Denise
This may better explain some of ithttp://clinicaltrials.gov/ct2/info/results
If a trial never proceeded beyond Phase I (testing of a compound on a small, typically I think 10-12, set of 'control' or 'healthy' individuals, i.e. those who have no relevant background disorders related to the indication of the drug and generally no serious or terminal health conditions), reports may not be legally required to be filed.
A Phase I is literally taking a compound that has come out of the lab, has been extensively worked up in synthesis and computer models, has been tested on appropriate animal subjects, and administering it to "healthy" subjects as complete controls to test for adverse reactions in humans, period.
As for the somewhat expanded, Phase II, and the multinational (typically) Phase III trials, those appear to have a year for their results to be examined and filed, and may apply for additional time under some circumstances, at least having giving a cursory look at the rules I saw there.
-- tidings
Posted by Phillipa on September 7, 2009, at 20:14:27
In reply to Re: Clinical trials.gov - Phillipa, posted by meltingpot on September 7, 2009, at 3:34:06
Hi hanging in there. Love Phillipa
This is the end of the thread.
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