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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Phillipa on September 1, 2009, at 21:51:25
Interesting read from the pcn era til now resistance to antibiotics grows serious issue. Phillipa
http://www.medscape.com/viewarticle/706845?src=mp&spon=24&uac=125268EY
Posted by seldomseen on September 2, 2009, at 4:54:57
In reply to Antibiotic Resistance From PCN To Now, posted by Phillipa on September 1, 2009, at 21:51:25
Just a couple side notes, a lot of the non-inferiority trials of 3rd and 4th generation antibiotics were very poorly done - allowing the "biocreep" of some truly inferior products onto the market.
I also really wish that, even if people were inappropriately precribed antibiotics, they would complete the course of the drug. To me, it's a public health issue rather than a personal choice at this time.
Posted by Phillipa on September 2, 2009, at 19:53:55
In reply to Re: Antibiotic Resistance From PCN To Now, posted by seldomseen on September 2, 2009, at 4:54:57
Seldom I agree too many people stop their antibiotics as soon as they start to feel well hence so many mutations of bacteria. Phillipa
Posted by yxibow on September 3, 2009, at 5:49:22
In reply to Re: Antibiotic Resistance From PCN To Now » seldomseen, posted by Phillipa on September 2, 2009, at 19:53:55
> Seldom I agree too many people stop their antibiotics as soon as they start to feel well hence so many mutations of bacteria. Phillipa
Yep... that's just one of the many reasons for resistance, including other things that I have already mentioned before on the board so I won't bother, but use of antibiotics in terms of -years- also obviously contributes.
There's personal resistance as to just how effective it is along with their own immune system and community resistance which is of course the primary problem.
http://en.wikipedia.org/wiki/Timeline_of_antibioticsis probably not an all-inclusive, but fairly lengthy list of antibiotics out there, a fair amount of which are in use in the US, some not any more, some in a few countries.
Penicillin V is still used for some conditions.
-- Jay
-- tidings
Posted by bleauberry on September 3, 2009, at 18:46:03
In reply to Antibiotic Resistance From PCN To Now, posted by Phillipa on September 1, 2009, at 21:51:25
Luckily there are a few antibiotics that have not developed resistance.
Even better, there are a few foods and herbs that do not develop resistance to even the toughest mutated bugs of all.
Since my issues are primarily in the Borellia, Babesia, and Bartonnel category, it is comforting to know that these bugs have not developed resistance.
There is more to the resistance pathology than most people are aware. How Vitamin D interacts is a crucial link. How the medicine is dosed can also be important. A constant steady state dosing strategy may fail due to resistance, when a pulsed strategy of that same med works like nuclear bomb.
The immune system is also a big player in the whole thing. If it is not being manipulated in the proper direction for the given pathology, meds will fall short of their job and be perceived as resistant.
It is not as straight forward or simple as it appears.
The most powerful antibiotic was invented by God many thousands of years ago and still to this day there is not a bug that can survive it. We put it on many of our foods for flavoring. In high concentrated doses, smelly breath, healthy heart, death to resistant bugs of all kinds.
Posted by yxibow on September 3, 2009, at 19:36:00
In reply to Re: Antibiotic Resistance From PCN To Now, posted by bleauberry on September 3, 2009, at 18:46:03
Tomato strains, not genetically modified, but discovered the "old fashioned ways", are disease-resistant, not disease-proof. Crop losses are always possibly and increasingly possible.The most recent developments of antibiotics come outside of artificial developments of fungus. They come from certain animal sources.
Tea tree oil has antiseptic properties, this has been observed, but some day too superbugs may develop from it.
Triclosan which has been used in antibiotic soaps is not as efective as it used to be. Who knows how long chlorhexidine gluconate, used in hospital washes and oral rinses will be effective.
For now we're pretty protected with Purell, I don't think it would be terribly convincing yet that bacteria can reside in 60% alcohol.
Just because an antimicrobial is "natural" (distilled alcohol and distilled tea tree oil are natural) doesn't mean it can gain resistance.
This is the end of the thread.
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