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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Phillipa on August 10, 2009, at 15:07:35
Seems now a coorolation between loss of smell which leads to loss of taste. So depression isn't the cause? Any meds to fix. I've been withoug smell for over six years which leads to loss of taste. And that's depressing anyone else experience this? And What's your reaction to newest study linking to lupus, alzheimers, and parkingsons too. May not be in this article. Thanks Phillipa ps also scizophenia????
Lupus May Lessen Sense of Smell
Finding Could Lead to Earlier Diagnosis of Disease, Researchers Say
By Bill Hendrick
WebMD Health NewsReviewed by Louise Chang, MDMay 7, 2006 -- People with lupus may be more likely to have a diminished sense of smell, a new study says.The finding may be significant, Israeli researchers say, because a loss of smell could be a symptom that would help doctors make an earlier diagnosis of lupus and other diseases.
Olfactory dysfunction is known to exist in various central nervous system disorders, such as Parkinsons disease, Alzheimers, schizophrenia, and multiple sclerosis.
The study, led by Yehuda Shoenfeld, MD, of Chaim Sheba Medical Center in Tel-Hashomer, Israel, involved 100 people, half of whom had systemic lupus erythematosus, or SLE, and half that did not have the disease. Lupus, an autoimmune disease, happens when the immune system attacks healthy tissues, causing inflammation, swelling, pain, and damage.
The researchers examined olfactory function (ability to smell) with three distinct Sniffin Sticks tests. In one, people were asked to identify a stick with an odor from sticks that had no smell. They also were tested to see if they could tell the difference between sticks of different smells. And the participants also were asked to identify a particular smell from among four options.
People with SLE showed significant olfactory dysfunction, compared to those in the control group, the researchers say. A greater proportion of SLE participants (46%) had decreased sense of smell compared to non-SLE participants (25%). Also, complete loss of smell was only seen in some SLE participants.
The study is published in the May issue of Arthritis & Rheumatism.
The study authors say that people with more active disease and past manifestations of the condition known as neuropsychiatric SLE or NPSLE had significantly lower total scores.
In a news release, the scientists say past research in mice has demonstrated a link between neuropsychiatric SLE and sense of smell.
Sense of smell is unfamiliar territory for rheumatologists and immunologists, but results from this and other studies demonstrate that an autoimmune mechanism may play a role in loss of smell, the researchers say.
Thus, smell decrement has been found to be an early and predictive sign in several CNS [central nervous system] diseases, and therefore might be a useful and easy tool for the physician in early diagnosis of CNS involvement in autoimmune diseases.
Posted by hyperfocus on August 13, 2009, at 23:31:16
In reply to Depression Or An Autoimmune Disease Loss Smell, posted by Phillipa on August 10, 2009, at 15:07:35
phillipa can you get in contact with a CNS specialist? There has to be a reason for it - can't just let it go untreated.
Posted by Alexanderfromdenmark on August 14, 2009, at 7:49:58
In reply to Depression Or An Autoimmune Disease Loss Smell, posted by Phillipa on August 10, 2009, at 15:07:35
> Seems now a coorolation between loss of smell which leads to loss of taste. So depression isn't the cause? Any meds to fix. I've been withoug smell for over six years which leads to loss of taste. And that's depressing anyone else experience this? And What's your reaction to newest study linking to lupus, alzheimers, and parkingsons too. May not be in this article. Thanks Phillipa ps also scizophenia????
>
> Lupus May Lessen Sense of Smell
> Finding Could Lead to Earlier Diagnosis of Disease, Researchers Say
> By Bill Hendrick
> WebMD Health NewsReviewed by Louise Chang, MDMay 7, 2006 -- People with lupus may be more likely to have a diminished sense of smell, a new study says.
>
> The finding may be significant, Israeli researchers say, because a loss of smell could be a symptom that would help doctors make an earlier diagnosis of lupus and other diseases.
>
> Olfactory dysfunction is known to exist in various central nervous system disorders, such as Parkinsons disease, Alzheimers, schizophrenia, and multiple sclerosis.
>
> The study, led by Yehuda Shoenfeld, MD, of Chaim Sheba Medical Center in Tel-Hashomer, Israel, involved 100 people, half of whom had systemic lupus erythematosus, or SLE, and half that did not have the disease. Lupus, an autoimmune disease, happens when the immune system attacks healthy tissues, causing inflammation, swelling, pain, and damage.
>
> The researchers examined olfactory function (ability to smell) with three distinct Sniffin Sticks tests. In one, people were asked to identify a stick with an odor from sticks that had no smell. They also were tested to see if they could tell the difference between sticks of different smells. And the participants also were asked to identify a particular smell from among four options.
>
> People with SLE showed significant olfactory dysfunction, compared to those in the control group, the researchers say. A greater proportion of SLE participants (46%) had decreased sense of smell compared to non-SLE participants (25%). Also, complete loss of smell was only seen in some SLE participants.
>
> The study is published in the May issue of Arthritis & Rheumatism.
>
> The study authors say that people with more active disease and past manifestations of the condition known as neuropsychiatric SLE or NPSLE had significantly lower total scores.
>
> In a news release, the scientists say past research in mice has demonstrated a link between neuropsychiatric SLE and sense of smell.
>
> Sense of smell is unfamiliar territory for rheumatologists and immunologists, but results from this and other studies demonstrate that an autoimmune mechanism may play a role in loss of smell, the researchers say.
>
> Thus, smell decrement has been found to be an early and predictive sign in several CNS [central nervous system] diseases, and therefore might be a useful and easy tool for the physician in early diagnosis of CNS involvement in autoimmune diseases.
>Loss of smell.. Hmmmm low testosterone, low thyroid?
Posted by Phillipa on August 14, 2009, at 19:16:54
In reply to Re: Depression Or An Autoimmune Disease Loss Smell, posted by Alexanderfromdenmark on August 14, 2009, at 7:49:58
Alexander is there a correlation between hasimotos thyroiditis and loss of taste and smell? As I've had it for l5 years and all was fine till after lasix surgery for distance in my eyes? At the time of loss I went to DC to a specialist and also Wake Forrest to taste and smell center. Did those smell strips, also different tastes. Tongue can taste sweet, salty, sour, bitter that's it. Was told to take prednisone for two weeks nothing then theophylline which I didn't take as it made no sense. There was a tiny microadenoma on pituitary. No one was concerned with it. It sure stinks? Love Phillipa
Posted by Alexanderfromdenmark on August 16, 2009, at 12:49:30
In reply to Depression Or An Autoimmune Disease Loss Smell, posted by Phillipa on August 10, 2009, at 15:07:35
http://www.endocrine-india.com/resource/LossOfSmell_InHypothy.htm
it could be. Or low estrogen or testosterone levels. That's being hormonal causes anyway.
Posted by Phillipa on August 16, 2009, at 20:11:35
In reply to Re: Depression Or An Autoimmune Disease Loss Smell, posted by Alexanderfromdenmark on August 16, 2009, at 12:49:30
Alexander I am diagnosed with autoimmune hasimotos thyroiditis and take synthroid and post mena pausal so what's the treatment now seriously? Phillipa
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