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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 22 of 22. This is the beginning of the thread.
Posted by mogger on August 10, 2009, at 21:00:15
Just wanted to share a very positive experience I have had with 100 mg Rilutek for ocd/gad/depression. I have noticed a massive decrease in anxiety and thus my mood has been uplifted significantly. I have a problem getting anxious traveling and it is helping so much. My mind has calmed down considerably without brain fog or confusion. I have only had minor sedation to complain of which is getting better. I should note though that it took a while to kick in, about five and half weeks to be exact. I noticed in article that they predicted Rilutek would not be a blockbuster success due to it's lengthy onset of action. They proposed using ketamine until rilutek kicked in. I am glad that I have stuck with it as after a couple of weeks of not feeling anything I almost threw in the towel. Here is an interesting article on ketamine that mentions rilutek.
http://articles.latimes.com/2007/aug/27/health/he-ketamine27
mogger
Posted by Phillipa on August 11, 2009, at 0:50:35
In reply to Rilutek success, posted by mogger on August 10, 2009, at 21:00:15
Mogger so glad your're doing better. Love Phillipa
Posted by shasling on August 11, 2009, at 19:51:04
In reply to Rilutek success, posted by mogger on August 10, 2009, at 21:00:15
Great article,especialy with the current meds all playing a role with serotonin.Maois however work much more complex then increasing just those 3 mentioned chemicals,they increase many others which is why there are many interactions with them.
Still there is room as the article mentioned to explore other compltly different avenues.I hope im still around when they decide to do it.
Posted by yxibow on August 11, 2009, at 21:09:04
In reply to Rilutek success, posted by mogger on August 10, 2009, at 21:00:15
Well I'm glad you have had some success -- I'm sure my unnamed insurance would balk at it since its sort of an orphan drug -- it costs more than $5 a pill and who knows what sort of dose is necessary.
Posted by mogger on August 12, 2009, at 0:15:50
In reply to Re: Rilutek success, posted by yxibow on August 11, 2009, at 21:09:04
Thank you phillipa! :)
Posted by mogger on August 12, 2009, at 0:29:41
In reply to Rilutek success, posted by mogger on August 10, 2009, at 21:00:15
I agree it is a very interesting article. Thankfully the rilutek costs only 15 dollars a month however I pay $592 a month for my health plan!
Posted by Phillipa on August 12, 2009, at 21:27:10
In reply to Re: Rilutek success, posted by mogger on August 12, 2009, at 0:15:50
Mogger your welcome. Yikes that's a high cost for your insurance!!!! Love Phillipa
Posted by uncouth on August 12, 2009, at 23:59:57
In reply to Rilutek success, posted by mogger on August 10, 2009, at 21:00:15
was this you or your pdoc's idea? if it was your pdoc, can you share his rationale? as opposed to trying namenda. he must be pretty experimental as there are only a few studies out there and we don't know what affectss glutamate inhibition will have on 'normals' or in the long term yet. strong possibility of it causing some dumb-drug effects that may be subtle...
Posted by SLS on August 13, 2009, at 5:27:44
In reply to Re: Rilutek success, posted by uncouth on August 12, 2009, at 23:59:57
I tried riluzole a few years ago. It didn't do anything at all. It didn't help and it didn't hurt. Memantine gave me a nice little improvement during the first week. Thereafter, it made me moderately worse. I had been taking antidepressants at the time.
I would try memantine before riluzole.
- Scott
Posted by yxibow on August 13, 2009, at 9:51:40
In reply to Re: Rilutek success » mogger, posted by Phillipa on August 12, 2009, at 21:27:10
> Mogger your welcome. Yikes that's a high cost for your insurance!!!! Love Phillipa
Don't get me started on the final tally of things for unnamed PPO....
I prefer the flexibility of them though, HMOs can be cheaper for some people but you have to go through so many hurdles.
-- Jay
Posted by mogger on September 19, 2009, at 21:34:15
In reply to Re: Rilutek success, posted by uncouth on August 12, 2009, at 23:59:57
absolutely right about the dumb side effects. I had to stop as I couldn't put a thought or sentence together after 4 months! Do you think that memantine would have this problem as well? Funny enough the side effects listed on Rilutek don't mention cognitive problems and the memantine side effect list does!
mogger
Posted by Phillipa on September 20, 2009, at 18:58:10
In reply to Re: Rilutek success, posted by mogger on September 19, 2009, at 21:34:15
Now I'm sorry. Phillipa
Posted by mogger on September 20, 2009, at 22:19:03
In reply to Re: Rilutek success » mogger, posted by Phillipa on September 20, 2009, at 18:58:10
Thankyou Phillipa for your kind thoughts. I am determined to get to the bottom of this disorder with relatively low side effects if possible! :) Hope you are well and have enjoyed your weekend,
mogger
Posted by Phillipa on September 21, 2009, at 19:46:47
In reply to Re: Rilutek success, posted by mogger on September 20, 2009, at 22:19:03
Mogger I sincerely hope you do. Sorry couldn't be of more help to you. Phillipa
Posted by Questionmark on September 29, 2009, at 22:52:21
In reply to Re: Rilutek success, posted by mogger on September 19, 2009, at 21:34:15
Da**, it.
I was so optimistic about glutamate inhibitors and, after reading this one article (see below), riluzole in particular. But from the posts in this thread i am once again disheartened.
I guess there Are no side effect-free cures-- and probably never will be.
...
Man, i'm so sick of this.http://www.primarypsychiatry.com/aspx/articledetail.aspx?articleid=645
Posted by SLS on September 30, 2009, at 0:24:31
In reply to Re: Rilutek success, posted by Questionmark on September 29, 2009, at 22:52:21
> Da**, it.
> I was so optimistic about glutamate inhibitors and, after reading this one article (see below), riluzole in particular. But from the posts in this thread i am once again disheartened.
> I guess there Are no side effect-free cures-- and probably never will be.
> ...
> Man, i'm so sick of this.
>
> http://www.primarypsychiatry.com/aspx/articledetail.aspx?articleid=645
You could try combining Namenda, Lamictal, and Topamax if you are looking for an antiglutamatergic therapy.
- Scott
Posted by uncouth on September 30, 2009, at 2:28:26
In reply to Re: Rilutek success, posted by SLS on September 30, 2009, at 0:24:31
...not to mention tianeptine and n-acetyl-cysteine and maybe even resveratrol and lithium
turns out lots of stuff may operate on glutamate.
Posted by topgun on January 17, 2011, at 21:58:26
In reply to Re: Rilutek success » mogger, posted by Phillipa on August 11, 2009, at 0:50:35
Posted by Mogger on January 17, 2011, at 22:10:47
In reply to Re: Rilutek success (nm), posted by topgun on January 17, 2011, at 21:58:26
Topgun what does (nm) mean?
Posted by Phillipa on January 18, 2011, at 18:06:40
In reply to Re: Rilutek success » topgun, posted by Mogger on January 17, 2011, at 22:10:47
Mogger means no message. Phillipa
Posted by mogger on January 19, 2011, at 12:06:33
In reply to Re: Rilutek success » Mogger, posted by Phillipa on January 18, 2011, at 18:06:40
Thanks Phillipa,
I wondering why topgun would put that there? Weird. Happy New Year to you.
Posted by Phillipa on January 19, 2011, at 20:22:32
In reply to Re: Rilutek success, posted by mogger on January 19, 2011, at 12:06:33
Mogger thanks and same to you!!!! Phillipa
This is the end of the thread.
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