Psycho-Babble Medication Thread 864058

Shown: posts 1 to 15 of 15. This is the beginning of the thread.

 

Fastest acting sleeping drug..?

Posted by jms600 on November 19, 2008, at 18:02:02

Does anyone know what the fastest acting sleeping drug is (other than barbiturates)?

I heard that Zolpidem is supposed to be the fastest, is this true??

Thanks!

 

Re: Fastest acting sleeping drug..? » jms600

Posted by Phillipa on November 19, 2008, at 20:30:46

In reply to Fastest acting sleeping drug..?, posted by jms600 on November 19, 2008, at 18:02:02

chloral hydrate with xanax being second in my opinion only. Phillipa

 

Re: Fastest acting sleeping drug..?

Posted by llurpsienoodle on November 19, 2008, at 20:44:39

In reply to Re: Fastest acting sleeping drug..? » jms600, posted by Phillipa on November 19, 2008, at 20:30:46

In my experience, sonata acts faster than zolpidem-- maybe because it's in a capsule, rather than a tablet?

it's available as generic now too. Zalpelon or somesuch

-Ll

 

Re: Fastest acting sleeping drug..? » jms600

Posted by raisinb on November 20, 2008, at 11:52:39

In reply to Fastest acting sleeping drug..?, posted by jms600 on November 19, 2008, at 18:02:02

Both Remeron and Lunesta act almost immediately for me.

 

Re: Fastest acting sleeping drug..?

Posted by bleauberry on November 20, 2008, at 20:36:01

In reply to Fastest acting sleeping drug..?, posted by jms600 on November 19, 2008, at 18:02:02

These meds all work differently from person to person. But my experience is that Lunesta is the fastest, then either Trazodone or Seroquel second fastest, and Remeron third fastest. All rather fast though. Personal preference on which one of them is a friend to you or not.

 

Re: Fastest acting sleeping drug..? » bleauberry

Posted by yxibow on November 20, 2008, at 23:58:21

In reply to Re: Fastest acting sleeping drug..?, posted by bleauberry on November 20, 2008, at 20:36:01

> These meds all work differently from person to person. But my experience is that Lunesta is the fastest, then either Trazodone or Seroquel second fastest, and Remeron third fastest. All rather fast though. Personal preference on which one of them is a friend to you or not.

I would say its entirely personal experience.

Trazodone would react first, Remeron and Seroquel next and Lunesta and all the pseudobenzodiazepines (Ambien, etc) last.


-- Jay

 

Re: Fastest acting sleeping drug..?

Posted by paxvox59 on November 21, 2008, at 15:05:54

In reply to Re: Fastest acting sleeping drug..? » bleauberry, posted by yxibow on November 20, 2008, at 23:58:21

True, mostly an individualized situation, but the old benzo "Halcion" sent me out the quickest. Seroquel works fine, but what about all those side effects? It was all I could get for the past two years, but I'm wondering about the long-term damage it may have done to me. I know that my Cholesterol was sky-high when I had it checked a few weeks ago, and blood sugar was 103, on the high end of normal. Guess it's a moot point since I ran out of Seroquel awhile back!

PAX

 

Re: Fastest acting sleeping drug..?

Posted by Mikez on November 24, 2008, at 15:28:00

In reply to Re: Fastest acting sleeping drug..?, posted by paxvox59 on November 21, 2008, at 15:05:54

hi paxvox, what does of Sq were u on?

 

Re: Fastest acting sleeping drug..?

Posted by cactus on November 26, 2008, at 20:34:54

In reply to Re: Fastest acting sleeping drug..?, posted by Mikez on November 24, 2008, at 15:28:00

for me it's halcion (triazolam) then mogadon (nitrazepam) and even though valium is not a sleep aid as such, it's pretty quick and helps with sleep. I found zopiclone, zoldipem, seroquel and clonazepam take quite a bit longer.

 

Re: Fastest acting sleeping drug..? » cactus

Posted by yxibow on November 28, 2008, at 3:39:27

In reply to Re: Fastest acting sleeping drug..?, posted by cactus on November 26, 2008, at 20:34:54

> for me it's halcion (triazolam) then mogadon (nitrazepam) and even though valium is not a sleep aid as such, it's pretty quick and helps with sleep. I found zopiclone, zoldipem, seroquel and clonazepam take quite a bit longer.

temazepam (Restoril), a sleep agent, is a metabolite of Valium.

 

Re: Fastest acting sleeping drug..?

Posted by Vincent_QC on November 30, 2008, at 11:53:55

In reply to Re: Fastest acting sleeping drug..? » cactus, posted by yxibow on November 28, 2008, at 3:39:27

> > for me it's halcion (triazolam) then mogadon (nitrazepam) and even though valium is not a sleep aid as such, it's pretty quick and helps with sleep. I found zopiclone, zoldipem, seroquel and clonazepam take quite a bit longer.
>
> temazepam (Restoril), a sleep agent, is a metabolite of Valium.

All of these drugs are from the benzo familly or metabolite of some of them. They only keep the metabolite who have more hypnotic proprieties...but they are not a good solution for insomnia cause after 1 week or 2, they already begin to loose their efficiency and you will endup with a more bad insomnia problem.

My experience make more sense if you use Trazodone (Desyrel) or Remeron (mirtazipine), because they don't loose their sedative effects and they also have some antidepressants action as well...IF you are under a MAOI like Nardil or Parnate, avoid Remeron because he act on the "NE" receptors so it's possible to have a hypersensitive crisis... just ask for Trazodone (Desyrel) drug...it come in a pill that you can split in 2 on one side and 3 on the other one....very srange form of pill to be honnest...lol You can have to adjust the dose on 2 or 3 days and it's possible to feel a little bit the hunghover feeling the morning after, but that's not permanent, this effect fade away fast.

Try to avoid all the "Z" drugs deriative from anxiolytics drugs, the ones I mention under this:

Zaleplon (Sonata), stay just 2 hours in the system...fast acting but if you wake up often in the midle of the night, you will not be able to sleep again without taking another one...Very ADDICTIVE .

Zolpidem (Ambien, Stilnoct), also stay only 2 hours in the blood...very addictive as well.

Zopiclone (Zimovane, Imovane), stay more than 5-6 hours in the blood. Slow onset of action, not very good because you will be a lot tired the day after...very addictive too...

Eszopiclone (Lunesta), stay 6 hours in the blood, also not very good for the hunghover feeling the day after....very addictive...

Trust me, I don't want to make a bad reputation of the "Non-benzodiazepines" deriative drugs, or even the benzodiazepines themself...

I'm on 20 mg/day of valium now, sometimes 25 mg...especially since I begin the Nardil this week...

The main problem with these drugs, is that the brains became addicted fast and the powerfull anxiolytic and sedative effect faded away very fast...

I think it's related with the gaba receptors...and how the benzo act on them. They block a sodium channel related to the gaba, well I think...not sure at 100%...After a while, the structure of the gaba receptor change and the benzo just stop working, so you need more of them to have the same effect. When you reach the point of the no limit return, your brains are totally changes and no benzodiazepines are able to change that and give to you again a relief of your insomnia or anxiety.

Some people here can argue with me on that, and say that non-benzodiazepines sleep aid are not addictive at all, especially when you never had a addiction problem to drugs or alcohol...but that's completly false. IF someone tell you this, it's probably because he's addicted himself on that drug.

I try several times to stop the valium or rivotril pills that I take since 2005...but I fail each time... I just succed to switch from Rivotril 8mg/day (equivalent to 160mg/day of Valium) to a low Valium dose of 20 mg/day, that's the best I can give for now...It's so freaking out to be addicted to something who is not working anymore, and it's also a lot frustrating...

For an example, I always stop cold turkey my antidepressants, anticonvulsives (Gabapentin, lyrica)and the antipsychotics pills I try, even after 3 months on them. The last one I stop was the Cipralex (Lexapro, escitalopram), 20 mg/day and I had no withdrawl effects...maybe just 2 days with a strange feeling...but that's nothing if I compare this with the times I try to stop cold turkey my Valium pills... Just switch from a benzo to another one is something really difficult.

Anyway i'm off the topic again... it was just my recommandation...

Ho and I don't recommended the Seroquel as well...because it cause to many side effects. It's a powerfull drug, too much often give as a sleep aid and to calm people at the hospital, but that's not good at all. If you want to feel like a zombie it's your choice, but I will completly forget it.

 

Re: Fastest acting sleeping drug..?

Posted by yxibow on December 1, 2008, at 13:52:13

In reply to Re: Fastest acting sleeping drug..?, posted by Vincent_QC on November 30, 2008, at 11:53:55

just ask for Trazodone (Desyrel) drug...it come in a pill that you can split in 2 on one side and 3 on the other one....very srange form of pill to be honnest

Only one maker of that I know of is making it any more, the ones I've gotten when I took it lately were a oblong shaped tablet with three ruler marks that could not possibly be broken that easily. But could just be the phamacy. Anyhow, Trazodone is a pretty icky way to sleep in my opinion, it is sort of overpowering and makes you stagger or faint.

Amitriptyline is a rather sedating TCA and with due caution, 10 mg per night can be used.

It will be extremely sedating the first dose I imagine no matter what if you haven't been exposed to TCAs/APs/strong antihistamines.



> Zopiclone (Zimovane, Imovane), stay more than 5-6 hours in the blood. Slow onset of action, not very good because you will be a lot tired the day after...very addictive too...
>
> Eszopiclone (Lunesta), stay 6 hours in the blood, also not very good for the hunghover feeling the day after....very addictive...
>

The above is the only one approved for dosing for more than 7 days or however long they're typically approved for. Lunesta, while not "addictive" -- none of the things that you mention are "addictive" for people who are not addicts.

It may be semantic, but I consider addictive use to be recreational or some form of pathology that may not be in the patient's hands, genetics, etc...

.....but is not the use of agents at a particular prescribed dose which are "habit forming", which basically means over a short or long period, of unknown length...

...they become less effective or lose their "zing", but the person keeps taking the same dose without increasing it on okay with a doctor (yes I have a problem now with getting off of a benzodiazepine, but there was, and still is a particular case by case use for it considering how rare this one is that I'm dealing with my life, but anyhow)....

....or possibly order it somehow on the streets or purloin it or whatever. I'm not trying to single out addicts, by the way by describing this, it is often genetically inclined, there is physical habituation, psychological habituation (e.g. with cigarettes, something in one's mouth, reaching for your matches, the patters one did), etc. I'm just hyper inflating what could be a scenario.


Anyhow, enough of that, Lunesta is approved for more medium term sleep use, and I would imagine though it isn't approved so, its precursor is also, although the new racemer may be a bit different. Ambien is for a much shorter period, although even that is sometimes dosed for a month or so.

There's also Ramelteon but that's pretty hit and miss, its supposedly much more powerful than melatonin in its targeting of receptors. It is not in the "habit forming" category.

Melatonin itself is something I would be careful with, the highest dose I saw was 5mg, and boy did I have some wierd night effects and nightmares.

It's a hormone, so that's the caution.

-- tidings

Jay

 

Re: Fastest acting sleeping drug..? » yxibow

Posted by Phillipa on December 1, 2008, at 20:08:21

In reply to Re: Fastest acting sleeping drug..?, posted by yxibow on December 1, 2008, at 13:52:13

Jay melatonin is a hormone. Before it was withdrawn from market took it and felt like I needed to remind myself to breath so didn't take it again. Love Phillipa

 

Re: Fastest acting sleeping drug..? » Phillipa

Posted by yxibow on December 1, 2008, at 23:40:39

In reply to Re: Fastest acting sleeping drug..? » yxibow, posted by Phillipa on December 1, 2008, at 20:08:21

> Jay melatonin is a hormone. Before it was withdrawn from market took it and felt like I needed to remind myself to breath so didn't take it again. Love Phillipa

Its not withdrawn from the market, its fully available in whatever dose you want up to about 5mg or as low as 500mcg. I did say in the above statement be cautious at the end, melatonin is a hormone so it could theoretically affect the HPA axis but that is an individual, unknown, and not tested (as are most all supplements). I was not suggesting that someone try it without thinking about what else they are on and what may or may not ail them physically and psychiatrically.

- Jay

 

Re: Fastest acting sleeping drug..? » yxibow

Posted by Phillipa on December 2, 2008, at 19:40:53

In reply to Re: Fastest acting sleeping drug..? » Phillipa, posted by yxibow on December 1, 2008, at 23:40:39

Jay no this was so many years ago wasn't on meds. Then it was recalled I know you can currently get it miscommunication. Phillipa


This is the end of the thread.


Show another thread

URL of post in thread:


Psycho-Babble Medication | Extras | FAQ


[dr. bob] Dr. Bob is Robert Hsiung, MD, bob@dr-bob.org

Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.