Psycho-Babble Medication Thread 857561

Shown: posts 1 to 6 of 6. This is the beginning of the thread.

 

generic ambien to avoid 'RDY 479'

Posted by elanor roosevelt on October 15, 2008, at 12:40:39

suffering from sleep deprivation
this generic does not work at all for me and brand ambien works just fine

if you have to get a generic ambien avoid this one

called the pharmacist
can't replace with brand
she suggested 30mg of resteral
have to call the pdoc

 

Re: generic ambien to avoid 'RDY 479' » elanor roosevelt

Posted by Phillipa on October 15, 2008, at 12:49:11

In reply to generic ambien to avoid 'RDY 479', posted by elanor roosevelt on October 15, 2008, at 12:40:39

Elanor good luck. Have you tried lunesta? Phillipa

 

Re: generic ambien to avoid 'RDY 479' » elanor roosevelt

Posted by yxibow on October 16, 2008, at 17:18:10

In reply to generic ambien to avoid 'RDY 479', posted by elanor roosevelt on October 15, 2008, at 12:40:39

> suffering from sleep deprivation
> this generic does not work at all for me and brand ambien works just fine
>
> if you have to get a generic ambien avoid this one
>
> called the pharmacist
> can't replace with brand
> she suggested 30mg of resteral
> have to call the pdoc


I don't know about these reports of generics not working -- I'll take your word for it, but there is also the rule of causality is not always causation. Ambien is only meant for short term use and it may also be that you have been on zolpidem too long -- maybe the "real" Ambien has slightly more in it but there is definitely a tolerance effect.

Restoril will create a tolerance effect quite quickly, it is a metabolite of Valium and it could be weeks or a few months before it may not be very effective for sleep.


But as they say, your miles may vary -- you may be more lucky with pseudobenzodiazepines and benzodiazepines, that is if you aren't already taking concurrently one, say klonopin or something. Cross tolerance is quite possible.


-- Jay

 

Re: generic ambien to avoid 'RDY 479'

Posted by elanor roosevelt on October 17, 2008, at 17:32:27

In reply to Re: generic ambien to avoid 'RDY 479' » elanor roosevelt, posted by yxibow on October 16, 2008, at 17:18:10

Jay
I had a number of bad nights before i even thought it might be the meds

i am sure it is
i have not, over 10 years,developed a tolerance for ambien
the change happened the day i started the new prescription

i am all for generic meds
but this one doesn't work and i am finding many reports online concerning the inconsistent quality of the med from this particular company

 

Re: generic ambien to avoid 'RDY 479' » elanor roosevelt

Posted by yxibow on October 17, 2008, at 19:34:40

In reply to Re: generic ambien to avoid 'RDY 479', posted by elanor roosevelt on October 17, 2008, at 17:32:27

> Jay
> I had a number of bad nights before i even thought it might be the meds
>
> i am sure it is
> i have not, over 10 years,developed a tolerance for ambien
> the change happened the day i started the new prescription
>
> i am all for generic meds
> but this one doesn't work and i am finding many reports online concerning the inconsistent quality of the med from this particular company
>

10 years -- my goodness, that's a long time on Ambien. But I'm sure your doctor has a reason or has observed you over the years.


Ambien "worked" or I actually "felt" it for one day -- it was one of the most interesting almost psychedelic experiences I've had on a psychotropic medication, it was like, come to sleep, its okay, follow me in as I pull you into happiness. And since then I've never "felt" anything.

I don't take it currently but I have had to take it at 20mg at a point when I was taking it to even sleep -- I still didn't "feel" a thing, no pull to get up from what I was doing and go to bed. It could have even been a partial placebo.

-- Jay

 

Re: generic ambien to avoid 'RDY 479'

Posted by bleauberry on October 18, 2008, at 9:58:23

In reply to generic ambien to avoid 'RDY 479', posted by elanor roosevelt on October 15, 2008, at 12:40:39

I can't tell you how many people have had bad reports of generic meds. Many many many. It is not just you. It is not someone's imagination.

No one knows how the fillers relate to absorption, or even if they somehow work in conjunction with the active ingredient at a molecular level. Different fillers, different drug. Similar, but different. As far as the active ingredient goes, generics are allowed I think a 8% variation. Which means if one dose is on the 8% low side and one is on the 8% high side, that is a 16% difference, almost a quarter of the dose. And exactly how they got to the end product called the active ingredient makes a difference. Chemistry stuff, like temperature heated, elapsed time in a melting state, other chemicals used in the process, and such.

I did fine at one time on brand name prozac. Also brand xanax. I did badly on the generics. I did a short trial of brand wellbutrin once and then soon followed with generic. Totally different, like night and day. I guarantee you it was not imagination or placebo, and in your case probably not as well.

Just my own opinion, but I think generics are unreliable. They work for some people. I think they should be available to try in order to reduce costs, but that if side effects are worse or condition deteriorates, then a return to the brand should be employed. And insurance companies should stay out of the business of playing doctors and chemists. Give the patient what they need to feel best and don't second guess the patient's life in the name of profit.

In a perfect world, I think everyone should be started on a brand name drug in order to duplicate original FDA clinical studies as close as possible (they were not done with generics). If the patient does well, try a switch to generic. If they still do well, great. If not, go back to brand. At a later date, do a retest and try generic again, this time from a different company. If they do great, cool. If not, get back on brand asap. An approach like that would give everyone a fair shot, including the patient and the insurance company.


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