Psycho-Babble Medication Thread 851526

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Effexor side effects- help! WHOAH!!!!

Posted by thinkingitover on September 11, 2008, at 15:01:57

I currently doing a cross taper from 37.5 MG of Zoloft to 50 MGS of Effexor... WHOAH. The side effects are KNARLY. Nervousness, sweatiness, derealization... AHHH!
Here's how I started... I dropped down to 25 MGS of Zoloft about 2 weeks ago for 5 days, then I swapped out 12.5 MGS of Zoloft for 25 MGS of Effexor (aplit in 2 doses, so 12.5 MGS twice a day, with the remaining 12.5 MGS of Zoloft)
Did that for 5 days, and then dropped the remaining 12.5 MGS of Zoloft, and added 12.5 MGS of effexor.... YIKES.
IS it possible that I can get away with holding at 37.5 MGS of Effexor? Could it be stronger than the Zoloft because boy am I feeling it!!!!!!

Is effexor stronger than the others? It doesn't feel like a discontinuation from the Zoloft, although it could be...
Any thoughts on this????? Is it stronger? Should I stay at 37.5 or move up to 50 MGS?
Anything I do, I run past my pdoc of course but need more insight.

 

Re: Effexor side effects- help! WHOAH!!!!

Posted by manic666 on September 12, 2008, at 3:12:43

In reply to Effexor side effects- help! WHOAH!!!!, posted by thinkingitover on September 11, 2008, at 15:01:57

hey friend i was on 225 velafaxine its same thing i came right of slow. it has some massive side effects to some an i was one .manic666

 

Re: Effexor side effects- help! (anyone?)

Posted by thinkingitover on September 12, 2008, at 7:31:17

In reply to Effexor side effects- help! WHOAH!!!!, posted by thinkingitover on September 11, 2008, at 15:01:57

Does anyone have any ideas on this?

> I currently doing a cross taper from 37.5 MG of Zoloft to 50 MGS of Effexor... WHOAH. The side effects are KNARLY. Nervousness, sweatiness, derealization... AHHH!
> Here's how I started... I dropped down to 25 MGS of Zoloft about 2 weeks ago for 5 days, then I swapped out 12.5 MGS of Zoloft for 25 MGS of Effexor (aplit in 2 doses, so 12.5 MGS twice a day, with the remaining 12.5 MGS of Zoloft)
> Did that for 5 days, and then dropped the remaining 12.5 MGS of Zoloft, and added 12.5 MGS of effexor.... YIKES.
> IS it possible that I can get away with holding at 37.5 MGS of Effexor? Could it be stronger than the Zoloft because boy am I feeling it!!!!!!
>
> Is effexor stronger than the others? It doesn't feel like a discontinuation from the Zoloft, although it could be...
> Any thoughts on this????? Is it stronger? Should I stay at 37.5 or move up to 50 MGS?
> Anything I do, I run past my pdoc of course but need more insight.

 

Re: Effexor side effects- help! (anyone?) ยป thinkingitover

Posted by Racer on September 12, 2008, at 19:20:45

In reply to Re: Effexor side effects- help! (anyone?), posted by thinkingitover on September 12, 2008, at 7:31:17

My guess, which is all this is, has to do with the cross taper part -- Zoloft and Effexor are different enough I'd bet you're concurrently dealing with discontinuation symptoms from Zoloft while also experiencing adjustment phase effects from Effexor.

The Generalized Gnarliness is probably a combination of both factors. The sweating may, indeed, be from the Effexor, I seem to remember it could do that for some people. The derealization could be from either factor, so I'd say give it a couple of weeks to see if it goes away. (Do get your blood pressure checked, though, in case this is somehow lowering it.)

Most drugs require a bit of adjustment, and there's always the question of how fast to titrate up. For myself, I usually tell my psychopharmacologist that I don't want to start at microdoses and go up as slowly as possible -- yes, it can mean more adjustment issues, but I'd rather go up sensibly and avoid an interminable wait to see if the medication will help. (He'll offer me, for example, to start Zoloft at 12.5 mg, but then I'd have to suffer through a much longer adjustment than if I just go ahead and start with 25mg or 50mg.) Others go the low and slow route, because it works better for them. Which is best is really a personal choice.

The point of all those words is that you know what works better for you -- a shorter titration, with a slightly larger dose increase? Or a longer, smoother titration? For most medications, it's a personal comfort thing.

My overall advice is that you might do very well on Effexor. I don't think you've mentioned why you're switching, but Effexor is a very good medication for many people.

By the way, are you talking about the immediate release formulation? If so, you would do very well to discuss with your doctor switching the the extended release Effexor XR.

Best luck.

 

Re: Effexor side effects- help! WHOAH!!!!

Posted by manic666 on September 13, 2008, at 4:56:45

In reply to Effexor side effects- help! WHOAH!!!!, posted by thinkingitover on September 11, 2008, at 15:01:57

i think you get the tablet form up to100mg after that you get slow release, maby the tablet his hitting you to fast.


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