Shown: posts 1 to 25 of 37. This is the beginning of the thread.
Posted by bleauberry on April 19, 2008, at 20:48:00
So in a magazine, as well as some place on the net, I read that Zoloft was the most widely prescribed antidepressant of 2007.
But here a psychobabble we don't see much of Zoloft. I wonder what's up with that?
Did the drug company just do a fantastic job of getting all doctors to prescribe it, or is it the one that doctors really see success with? Hard to tell. I would have thought for sure that Lexapro or Effexor would have beat out Zoloft. But they didn't. And from all the Cymbalta ads I've seen and all the Duloxetine trivia posted all over doctor's offices, I'm surprised Lilly didn't come out on top.
Anyway, Zoloft, I know you're out there. Why so scarce at pbabble?
Posted by Phillipa on April 19, 2008, at 20:54:18
In reply to Zoloft Question, posted by bleauberry on April 19, 2008, at 20:48:00
Well my sister and her Daughter and my Son all took it and me for a short while at a low dose. All I know is my sister and neice love it. Phillipa
Posted by Justherself54 on April 19, 2008, at 21:44:48
In reply to Zoloft Question, posted by bleauberry on April 19, 2008, at 20:48:00
Good question. I would still be on it if not for the dreaded poop out I get from all AD's so far. It was easy to go on and easy to come off and worked very well. Lexapro worked well too but I had a real flattened effect from it. Zoloft just seemed to be the "easiest" AD I've taken. I miss it!
Posted by bissie66 on April 19, 2008, at 21:51:39
In reply to Re: Zoloft Question, posted by Justherself54 on April 19, 2008, at 21:44:48
Ditto. poop-out.
Posted by Maxime on April 19, 2008, at 23:07:56
In reply to Zoloft Question, posted by bleauberry on April 19, 2008, at 20:48:00
I was on it in 2007 and the apathy it caused (plus the natural occuring apathy) was more than I could handle.
Maxime
Posted by Phillipa on April 20, 2008, at 13:34:06
In reply to Zoloft Question, posted by bleauberry on April 19, 2008, at 20:48:00
Had to answer again maybe it works? Lexapro too? Just a thought. Love Phillipa
Posted by bulldog2 on April 20, 2008, at 14:17:15
In reply to Zoloft Question, posted by bleauberry on April 19, 2008, at 20:48:00
> So in a magazine, as well as some place on the net, I read that Zoloft was the most widely prescribed antidepressant of 2007.
>
> But here a psychobabble we don't see much of Zoloft. I wonder what's up with that?
>
> Did the drug company just do a fantastic job of getting all doctors to prescribe it, or is it the one that doctors really see success with? Hard to tell. I would have thought for sure that Lexapro or Effexor would have beat out Zoloft. But they didn't. And from all the Cymbalta ads I've seen and all the Duloxetine trivia posted all over doctor's offices, I'm surprised Lilly didn't come out on top.
>
> Anyway, Zoloft, I know you're out there. Why so scarce at pbabble?Zoloft is now generic. Drug companies like to push drugs still on patent. Zoloft is very good for one who needs an activating AD. Not as activating as prozac and also hits dopamine a bit.
Posted by bulldog2 on April 20, 2008, at 14:17:28
In reply to Zoloft Question, posted by bleauberry on April 19, 2008, at 20:48:00
> So in a magazine, as well as some place on the net, I read that Zoloft was the most widely prescribed antidepressant of 2007.
>
> But here a psychobabble we don't see much of Zoloft. I wonder what's up with that?
>
> Did the drug company just do a fantastic job of getting all doctors to prescribe it, or is it the one that doctors really see success with? Hard to tell. I would have thought for sure that Lexapro or Effexor would have beat out Zoloft. But they didn't. And from all the Cymbalta ads I've seen and all the Duloxetine trivia posted all over doctor's offices, I'm surprised Lilly didn't come out on top.
>
> Anyway, Zoloft, I know you're out there. Why so scarce at pbabble?Zoloft is now generic. Drug companies like to push drugs still on patent. Zoloft is very good for one who needs an activating AD. Not as activating as prozac and also hits dopamine a bit.
Posted by Phillipa on April 20, 2008, at 16:30:52
In reply to Re: Zoloft Question, posted by bulldog2 on April 20, 2008, at 14:17:28
Humm at what dose was it activating as didn't touch me at the 50mg I was only for two months? Love Phillipa
Posted by Justherself54 on April 20, 2008, at 17:14:07
In reply to Re: Zoloft Question » bulldog2, posted by Phillipa on April 20, 2008, at 16:30:52
> Humm at what dose was it activating as didn't touch me at the 50mg I was only for two months? Love Phillipa
My GP once told me that 50 mg was like peeing in the wind (although he didn't use the word peeing - he is known for his lovely bedside manner). 100 mg is what worked for me. Tried going to 200 when poop out was happening but no go...sigh...
Posted by bulldog2 on April 20, 2008, at 17:27:13
In reply to Re: Zoloft Question » bulldog2, posted by Phillipa on April 20, 2008, at 16:30:52
> Humm at what dose was it activating as didn't touch me at the 50mg I was only for two months? Love Phillipa
Well the problem was my gp at the time was a moron. He told me to stop my benzos cold turkey because the zoloft would take care of my anxiety. I followed his directions and within days my bp had soared and my anxiety was unbelievable. The dose of zoloft was 50 mg. Had to stop because bp was 170 - 110. Think stopping the ativan cold turkey was a very bad idea.
Posted by Fathe on April 20, 2008, at 17:37:57
In reply to Re: Zoloft QuestionPhillipa, posted by Justherself54 on April 20, 2008, at 17:14:07
Hi
I am kind of new here so I apologize upfront for asking - I see several people mention the term "poop out" when refering to extended use of SSRI's. What does that indicate - the medication reached its maximum benefit? Thanks !!
Lee Ellen
manner). 100 mg is what worked for me. Tried going to 200 when poop out was happening but no go...sigh...
>
Posted by Phillipa on April 20, 2008, at 18:25:03
In reply to Re: Zoloft QuestionPhillipa, posted by Justherself54 on April 20, 2008, at 17:14:07
Couldn't you have gone higher and added ad ad booster maybe a mood stabalizer or now Deplin? Just suggestions. Love Phillipa
Posted by Phillipa on April 20, 2008, at 18:26:10
In reply to Re: Zoloft QuestionPhillipa, posted by Fathe on April 20, 2008, at 17:37:57
Faith poop out is a term when a med stops working for you that used to work and no longer does. Love Phillipa
Posted by Phillipa on April 20, 2008, at 18:28:45
In reply to Re: Zoloft Question, posted by bulldog2 on April 20, 2008, at 17:27:13
Bulldog oh wow must have been horrible. Have yet to have an SSRI eliminate or put a dent in my anxiety. Love Phillipa
Posted by undopaminergic on April 20, 2008, at 20:54:04
In reply to Zoloft Question, posted by bleauberry on April 19, 2008, at 20:48:00
Zoloft (sertraline) is the second most potent SSRI, after Paxil/Seroxat (paroxetine), and has a much more favourable side-effect profile and much lower potential for interactions with other drugs (only surpassed by [es]citalopram in this regard). Furthermore, it has a half-life of about 26 hours, which is suitable for once-daily dosing and titration at weekly intervals, and if you need to quit it, it doesn't stay in your bloodstream for ever like Prozac, so you don't have to wait a month before starting a MAOI. It's a clean SSRI with no known affinities for neurotransmitter receptors or non-serotonin transporters, other than a very slight potency for dopamine reuptake inhibition, which may serve to make the drug a bit more stimulating and pleasant.
It's probably the ideal drug for anyone who might benefit from a serotonergic agent. Unfortunately, I'm not one of them, although I did find it slighly wakefulness-promoting - the very opposite effect of the hypnotic paroxetine. It wasn't quite as tolerable as fluoxetine, but that is only because sertraline is a more potent serotonergic agent, which is precisely what it was meant to be.
Since Zoloft is just about the perfect serotonergic agent, and since seronergic drugs are (or were, in 2007) in vogue, why wouldn't it be the most popular? The reason why it's rarely mentioned here, is because those who come here have tried several serotonergic agents and found them all ineffective, or only briefly or partially effective.
Posted by Phillipa on April 20, 2008, at 21:05:05
In reply to Re: Zoloft Question, posted by undopaminergic on April 20, 2008, at 20:54:04
Thanks from what I understand from family no weight gain as sister went from paxil to it as she did gain a lot of weight on paxil. I myself on l0mg of paxil was quite thin on the med and that was with 4-6 beers a night. But then I was working 3-ll and probably burned more calories. Love Phillipa
Posted by Racer on April 20, 2008, at 23:41:28
In reply to Re: Zoloft Question, posted by undopaminergic on April 20, 2008, at 20:54:04
>The reason why it's rarely mentioned here, is because those who come here have tried several serotonergic agents and found them all ineffective, or only briefly or partially effective.
And/or briefly, partially effective with intolerable adverse effects...
Zoloft was the best of the SSRIs for me -- but I can't stand the flattening. I just don't feel as though I'm living, I can't care about anything, have no motivation to do anything at all, and eventually even talking is too much trouble. (That's at 25mg, too, so I can't even blame the dose being too high!)
Thank you for your analysis, it was very clear, and very informative.
Posted by Justherself54 on April 20, 2008, at 23:44:58
In reply to Re: Zoloft QuestionPhillipa » Justherself54, posted by Phillipa on April 20, 2008, at 18:25:03
At 200 my guts couldn't tolerate it and it was still pooping out. I can't tolerate mood stabilizers and I haven't asked my pdoc about Deplin as too much going on right now with withdrawals.
> Couldn't you have gone higher and added ad ad booster maybe a mood stabalizer or now Deplin? Just suggestions. Love Phillipa
Posted by Phillipa on April 21, 2008, at 12:09:51
In reply to Re: Zoloft QuestionPhillipa, posted by Justherself54 on April 20, 2008, at 23:44:58
Oh you must be from what I've read only and SSRI responder as it does effect the gut right? If it affects the gut so badly is this an indication of an ad working for you? Truly I don't know. What I do know is my heart goes out to you with the horrible withdrawl from the nardil so sorry. I did have zaps when only that tiny smidgen of paxil at l0mg was discontinued as my Son was coming to live with us and he didn't believe in ad's and wanted to please him so bit off a small piece daily and that helped anyway to do that? Love Phillipa
Posted by Phillipa on April 21, 2008, at 12:14:47
In reply to And/or... » undopaminergic, posted by Racer on April 20, 2008, at 23:41:28
Racer that is a low dose. No wonder pdocs are starting doses lower than normal for those that are med sensitive. But if I can tolerate a higher dose than you what do you think it means? That I am an SSRI responder or a nonresponder I really don't know my knowledge isn't that understanding of neurotransmitters get that SSRI's affect the gut but for some reason don't with me? Is that good or bad? Thanks Phillipa
Posted by Phillipa on April 21, 2008, at 12:17:30
In reply to Re: Zoloft QuestionPhillipa, posted by Justherself54 on April 20, 2008, at 23:44:58
Same with the lexapro? Love Phillipa
Posted by Phillipa on April 21, 2008, at 13:03:51
In reply to Re: Zoloft QuestionPhillipa » Justherself54, posted by Phillipa on April 21, 2008, at 12:09:51
Actually why I assumed it was nardil you were withdrawing from is totally wrong of me as I don't know guess it was on my mind from so many wanting me on it. Apologies. Phillipa
Posted by Phillipa on April 21, 2008, at 13:05:06
In reply to Re: Zoloft QuestionPhillipa » Phillipa, posted by Phillipa on April 21, 2008, at 13:03:51
Posted by bissie66 on April 21, 2008, at 14:29:44
In reply to Zoloft Question, posted by bleauberry on April 19, 2008, at 20:48:00
zoloft poops out for me really quickly, but i now take it for PMS, just a few days, then stop, then take it again the next month for just a few days. however, i can't take it consistently or it just poops out. weird.
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