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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 15 of 15. This is the beginning of the thread.
Posted by henryo on January 25, 2008, at 15:50:13
DEPLIN what's the scoop
Posted by Phillipa on January 26, 2008, at 0:13:23
In reply to DEPLIN is it working? DEPLIN, posted by henryo on January 25, 2008, at 15:50:13
Been about two weeks for me at 7.5. Third day felt good with energy now it's gone but remembered a word tonight hadn't remembered in years. Are you thinking of trying it? On the website is a coupon can run off give to the pharmacy I got a third off and the Deplin company is supposed to send me a card so I always get that discount. Scott did say for ad effects 4 weeks or so. Phillipa
Posted by henryo on January 26, 2008, at 13:43:11
In reply to Re: DEPLIN is it working? DEPLIN » henryo, posted by Phillipa on January 26, 2008, at 0:13:23
Not thinking of trying: I'm on it for two plus months now. It is fantastic for me. Life changing. Amazing.
Posted by henryo on January 26, 2008, at 13:45:31
In reply to Re: DEPLIN is it working? DEPLIN » henryo, posted by Phillipa on January 26, 2008, at 0:13:23
What else are you on. I wonder about upping the dose of Deplin. I am a believer.
Posted by iforgotmypassword on January 26, 2008, at 14:59:48
In reply to Re: DEPLIN is it working? DEPLIN, posted by henryo on January 26, 2008, at 13:43:11
> Not thinking of trying: I'm on it for two plus months now. It is fantastic for me. Life changing. Amazing.
that's really, really good. :) i want to try it to see if it can help me, too.
i was wondering have you noticed any fluctuations that the drug has? like, does the beneficial effect fade later in the day, as the hours get further from your last dose? has there been any degree of poop-out? we're the initial weeks even slightly better than now? any sign of fading?
also, how long did it take to help? is there a beneficial effect right away? does it take weeks to get to full benefit?
if you can answer any of this, thanks so much! :)
Posted by Phillipa on January 26, 2008, at 21:03:35
In reply to Re: DEPLIN is it working? DEPLIN » henryo, posted by iforgotmypassword on January 26, 2008, at 14:59:48
I had one day third where I felt better don't want to rish the pernicious anemia so think I'll go off. And it was not giving any side effects or anything but health is more important to me. Phillipa ps why doesn't the website mention anemia and the b12 and P5P? I don't understand?
Posted by henryo on January 28, 2008, at 0:13:11
In reply to Re: DEPLIN is it working? DEPLIN » henryo, posted by iforgotmypassword on January 26, 2008, at 14:59:48
I don't want to sound overly optimistic but this stuff was the golden bullet for me. Worked right away, no fading. I just stopped feeling any of the debilitating enervating pain that I've lived with for decades. I wish it worked for everybody like this. It's life changing.
Posted by henryo on January 28, 2008, at 1:03:41
In reply to Re: DEPLIN is it working? DEPLIN » iforgotmypassword, posted by Phillipa on January 26, 2008, at 21:03:35
Deplin could mask a B12 deficiency. It doesnt cause it.
I want somebody to chase down the loose ends on the whole alcoholism depression and anemia thing. They seem interwoven in some way. Anemia drugs are often tested on chronic alcoholics, because they are all anemic. And I bet they are depressed too. It makes me very curious about L-Methylfolate and other nutritional implications for mental illness.
Is there some common thread amongst alcoholics like an inability to metabolize folates? Bill Wilson used to get Niacin injections. Niacin is a B vitamin. He had terrible depression. He called it despondency. Makes you wonder. I want them to try the Deplin on A) alcoholics and B) depressed people not even taking other meds and C) anemic people.
It could be that even if you are eating all the iron you can get it can't bind to the red blood cells with out some precursor like L-Methylfolate. If your body for some reason can't make L-Methylfolate very well then folic acid and other B's are no help. Hence you have depression and are at greater risk to abuse alcohol and if so become anemic.
You could work that sequence several other ways as well.
I know this is the medication board but Deplin does require a prescription.
Posted by henryo on January 28, 2008, at 1:13:10
In reply to Re: DEPLIN is it working? DEPLIN » henryo, posted by iforgotmypassword on January 26, 2008, at 14:59:48
It is not a drug its "medical food" ain't that crazy?
No poop out. For me it worked right away. Didn't build over weeks or taper off. No weight gain no sexual side effects.
I guess it was exactly what I needed. Read my first post from weeks ago.
Posted by Phillipa on January 28, 2008, at 11:58:25
In reply to Re: DEPLIN is it working? DEPLIN, posted by henryo on January 28, 2008, at 1:13:10
Can you provide a link by the way just sent you a babblemail. Phillipa And I'm still on the 7.5 mg deplin nothing though don't get it??????
Posted by Ron Hill on January 30, 2008, at 0:15:51
In reply to Re: DEPLIN is it working? DEPLIN, posted by henryo on January 28, 2008, at 1:03:41
Hey Henry O,
How's it going? I'm very happy to hear of your great response to Deplin.
> Deplin could mask a B12 deficiency. It doesnt cause it.
Yes, L-methylfolate can indeed mask a B12 deficiency.
But, further, when the pt is taking a high dosage of folate, the pt's B12 level is reduced unless there is supplementation.
Please see my post to you and others in a thread below.
Best wishes my friend with your continued benefit from Deplin.
-- Ron
BP II w/ultra rapid cycling; and OCPD
300 mg/day Trileptal
200 mg/day Lamictal
250 mg/day Keppra
82.5 mg/day Nardil
25 mg/day Topamax
7.5 mg/day Deplin
Posted by Ron Hill on January 30, 2008, at 4:56:26
In reply to Re: DEPLIN is it working? DEPLIN, posted by henryo on January 28, 2008, at 1:03:41
Henry O,
Please take time to read the linked post and watch the presentation:
http://www.dr-bob.org/babble/20080124/msgs/809694.html
The presentation does a good job of explaining why methyl-B12 needs to be added when L-methylfolate is used.
-- Ron
Posted by henryo on February 4, 2008, at 22:00:05
In reply to L-methylfolate reduces methyl-B12 » henryo, posted by Ron Hill on January 30, 2008, at 4:56:26
Thanks for the links. I'll be out of town for the next ten days.
The Deplin is working very very well and I have every intention of it continuing that way.
Posted by deniseuk190466 on February 5, 2008, at 15:31:58
In reply to Re: L-methylfolate reduces methyl-B12, posted by henryo on February 4, 2008, at 22:00:05
Hi,
What else had you tried before trying Deplin? I'm just wondering if maybe you would have responded to most Antidepressants anyway. In other words just trying to get an idea of how med resistant you are.
Thanks....Denise
Posted by henryo on February 14, 2008, at 1:31:23
In reply to To henryo, posted by deniseuk190466 on February 5, 2008, at 15:31:58
Many, many meds. I don't even want to think about it. I've been posting here for almost ten years. It might not work for anyone else. I have other Deplin posts too. Henry
This is the end of the thread.
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