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Dr. Bob is Robert Hsiung, MD,
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Posted by roadrunner on January 23, 2008, at 21:02:58
Is it necessary to take klonopin to prevent seizures from clozaril? I am taking 300mg clozaril/day with 1 mg klonopin. Can I reduce the klonopin safely?
Posted by yxibow on January 23, 2008, at 22:53:17
In reply to klonopin for clozaril, posted by roadrunner on January 23, 2008, at 21:02:58
> Is it necessary to take klonopin to prevent seizures from clozaril? I am taking 300mg clozaril/day with 1 mg klonopin. Can I reduce the klonopin safely?
Generally benzodiazepines are contraindicated with Clozaril and if there is worries of seizures another AED such as Depakote or Lamictal (they can do other things like change plasma levels but not respiratory depression) or Trileptal should probably be used, but with careful use and monitoring of low dosage benzodiazepines I suppose respiratory depression (the major contraindication) isn't a major issue.
This is the end of the thread.
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