Shown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by amigan on January 2, 2008, at 1:18:36
Hello.
Everytime i take Trazodone my heart starts racing. It beats stronger and faster! Not a good thing if you are trying to sleep... Sometimes i have to take a b-blocker to calm it down.
I have checked the pharmacological profile of this drug and i can't find anything that could explain why it causing me this symptom:
No adrenergic/sympathomimetic, anti-cholinergic or dopaminergic action that would justify such symptom! Could someone help me understand this?
Posted by Mishal on January 2, 2008, at 6:45:07
In reply to Why do i get racing-heart on Trazodone?, posted by amigan on January 2, 2008, at 1:18:36
Trazodone has alpha-adrenergic blocking actions, hence can cause tachycardia. I wonder why should you take it for sleeping when alternatives are there.
Posted by Amigan on January 2, 2008, at 9:50:54
In reply to Re: Why do i get racing-heart on Trazodone? » amigan, posted by Mishal on January 2, 2008, at 6:45:07
>
> Trazodone has alpha-adrenergic blocking actions, hence can cause tachycardia. I wonder why should you take it for sleeping when alternatives are there.I know that there are better alternatives, but this one seems to work best for me, in moclobemide-induced insomnia.
But, doesn't "alpha-adrenergic BLOCKING" mean that it antagonizes the action of adrenaline? Shouldn't this cause bradycardia, instead? Or perhaps you are talking about pre-synaptic blocking of the autoreceptors? That would lead to an increase of (nor)adrenaline..
Posted by Phillipa on January 2, 2008, at 12:17:58
In reply to Re: Why do i get racing-heart on Trazodone? » Mishal, posted by Amigan on January 2, 2008, at 9:50:54
Just a thought have you asked your doc that prescribes it for you and assuming your heart is fine. Phillipa
Posted by yxibow on January 4, 2008, at 2:19:55
In reply to Why do i get racing-heart on Trazodone?, posted by amigan on January 2, 2008, at 1:18:36
> Hello.
> Everytime i take Trazodone my heart starts racing. It beats stronger and faster! Not a good thing if you are trying to sleep... Sometimes i have to take a b-blocker to calm it down.
> I have checked the pharmacological profile of this drug and i can't find anything that could explain why it causing me this symptom:
> No adrenergic/sympathomimetic, anti-cholinergic or dopaminergic action that would justify such symptom! Could someone help me understand this?
>It is an idiosyncratic reaction to Trazodone. I had it at one point so bad that I called 911 but it calmed down while I was talking to the dispatcher.
I have never had it since.
But, since you have had this reaction, you might want to try another agent such as doxepin unless your GP carries out an EKG. Its not something you want to have repeatedly.
This is the end of the thread.
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