Psycho-Babble Medication Thread 791143

Shown: posts 1 to 4 of 4. This is the beginning of the thread.

clonidine

Posted by spaceboy68 on October 24, 2007, at 15:11:42

I was recently given a script for clonidine
to help with the insomnia I have developed
Does clonidine negate the effects of the
the anitidepressants I am taking
(Parnate and desipramine)or does as some
web sites claim it enhances noradgenic
activity???

Re: clonidine

Posted by amigan on October 24, 2007, at 18:58:05

In reply to clonidine, posted by spaceboy68 on October 24, 2007, at 15:11:42

> I was recently given a script for clonidine
> to help with the insomnia I have developed

Clonidine for insomnia alone?! That's not a very good choise you know... Perhaps you have another condition that clonidine treats, like ADHD? That would make more sense.

> Does clonidine negate the effects of the
> the anitidepressants I am taking
> (Parnate and desipramine)

Afaik, TCAs (desipramine) reduces the potency of clonidine.

> or does as some
> web sites claim it enhances noradgenic
> activity???

I'm not sure of this, but it causes deplition of NE.

Re: clonidine

Posted by linkadge on October 24, 2007, at 19:43:49

In reply to clonidine, posted by spaceboy68 on October 24, 2007, at 15:11:42

Clonidine reduces norepineprine release. It may be that noradrenergic hyperactivity from parnate and desipramine is causing the insomnia, in which case clinidine may help some.

If you time it right it probably will not cancel out the antidepressant effect of the two other meds you are taking.

Linkadge

Re: clonidine

Posted by amigan on October 24, 2007, at 20:08:46

In reply to Re: clonidine, posted by linkadge on October 24, 2007, at 19:43:49

Wouldn't it be more reasonable to trim desipramine, for example, instead of adding a 3rd medicine that fights its action?

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