![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by iforgotmypassword on September 28, 2007, at 18:21:40
this is from wikipedia, and not flawlessly edited, but i am wondering if there is any truth to it, or if anyone else has experienced anything like it describes.
"low doses of the newer atypical antipsychotics olanzapine (Zyprexa), quetiapine (Seroquel) and risperidone (Risperdal) have also been found to be useful as adjuncts in the treatment of OCD. The use of antipsychotics in OCD must be undertaken carefully however, since although there is very strong evidence that at low doses they are beneficial (most likely due to their dopamine receptor antagonism), at high doses these same antipsychotics have proven to cause dramatic obsessive-compulsive symptoms even in those who don't normally have OCD. This is most likely due to the antagonism of 5-HT2A receptors becoming very prominent at these doses and outweighing the benefits of dopamine antagonsim."
Posted by iforgotmypassword on September 28, 2007, at 18:29:22
In reply to antipsychotics can cause OCD sx?, posted by iforgotmypassword on September 28, 2007, at 18:21:40
i mean to say that it does not cite sources, rather than it is simply just from wikipedia. from a political standpoint i'm obligated to adore wikipedia. ;-)
thankyou.
Posted by Phillipa on September 28, 2007, at 20:29:09
In reply to oops, btw..., posted by iforgotmypassword on September 28, 2007, at 18:29:22
Well I wonder why OCD takes longer for an SSRI to work than other disorders. As far as the antipsychotics seems to contradict itself. Wondering if all the step I had as a young adult gave it to me as I had a year with step all the time. And now I have autoimmune disorders. Intersting thanks Phillipa
Posted by linkadge on September 28, 2007, at 23:02:58
In reply to Re: oops, btw... » iforgotmypassword, posted by Phillipa on September 28, 2007, at 20:29:09
*Absolutely* Risperidal produced prominant OCD symptoms in my mother which abated upon withdrawl.
SSRI's are proposed to work in OCD by activating gabaergic responces in the frontal cortex via 5-ht2a activation.
Linkadge
Posted by iforgotmypassword on September 29, 2007, at 12:49:29
In reply to Re: oops, btw..., posted by linkadge on September 28, 2007, at 23:02:58
Posted by linkadge on September 29, 2007, at 15:34:03
In reply to interesting. more reading material available? (nm) » linkadge, posted by iforgotmypassword on September 29, 2007, at 12:49:29
Not exactly sure. I have just read bits a pieces.
I know that inositol is supposed to work in OCD via its seccond messenger effects from 5-hta/c acitvation. Also mushrooms and mescalin 5-ht2a/c agonists have some theraptutic effect in OCD.
Cyproheptadine, a 5-ht2a/c antagonist, reverses anti-OCD effect but not antidepressant effect of SSRI's (according to one study)
Linkadge
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.