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Dr. Bob is Robert Hsiung, MD,
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Posted by sdworaczyk on July 5, 2007, at 8:46:29
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by Ladybug56 on July 4, 2007, at 16:07:08
Just an FYI...I asked my doctor to fill my last prescription for "name brand only" for the 300mg which was more expensive, this month we tried writing it for me to take two 150 mg and it was significantly cheaper, since there is no generic for the 150mg yet, most insurance companies will pay more because it is not a special request...just wanted to pass this along..also I called around to several pharmacies and found that there is actually a big difference in price between the pharmacies.
Posted by i4gotmy_sn on July 10, 2007, at 4:12:54
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by sdworaczyk on July 5, 2007, at 8:46:29
Last night was the last time I took budeprion XL 300mg and it will be the last time ever. What a joke! Unfortunately I'm financially disadvantaged at the age of 20, so I can't purchased the name brand. I had been taking Wellbutrin XL 300mg for a while now and I was fine while on it. I can even so far as to say that I was decent on bupropion 300mg. It had little to no difference. I felt like I was just not getting a full effect of 300mg, that's all. It was okay and not horrible to deal with.
Considering I get my meds free or really cheap, I felt I had nothing to complain about. I told my psychiatrist, who's a total jerk for the record what had been going on when I took this weird, big, yellow pills that looked nothing like the name brand or the other generic I had. He made me feel like some sort of alien, as if what was coming out of my mouth was mindless babble. I knew what I had been feeling, but somehow to him, I was a lier. Like many others I thought my pharmacy made a mistake.
Tomorrow or within the next few days I have another refill to pick up. I flushed the remainder of what I had down the toilet. If I receive the same thing (yellow budeprion), I'm going to just hand it back to them and say "you guys obviously need the money, more than I need this". Why take something that's makes me worse off than I normally am?!
I really didn't want to experience side-effects of coming off of it, that's why I didn't stop taking the budeprion. It made me extreme edgy, easily prone to bouts of anger, and unhappy. Feeling like there was no reason to live. I felt that I was dependent on these pills and it played a toll on my self-esteem.
I almost lost some "friends" from the handful of episodes that I had. I had a complete mental breakdown and crying wasn't enough anymore. I had to hit pillows or squeeze the closest thing to me as hard as I could. I don't know if what I'm saying is making sense to any of you reading this, but hopefully. I apologize for the long entry. Long story, short: Wellbutrin XL 300mg = Excellent! Bupropion XL 300mg = Pretty good. Buderprion XL 300mg = Unbelievably unnecessary and not worth it!
Posted by i4gotmy_sn on July 10, 2007, at 4:18:20
In reply to Re: Budeprion (Generic) vs. Wellbutrin » sdworaczyk, posted by i4gotmy_sn on July 10, 2007, at 4:12:54
Last night was the last time I took budeprion XL 300mg and it will be the last time ever. What a joke! Unfortunately I'm financially disadvantaged at the age of 20, so I can't purchased the name brand. I had been taking Wellbutrin XL 300mg for a while now and I was fine while on it. I can even so far as to say that I was decent on bupropion 300mg. It had little to no difference. I felt like I was just not getting a full effect of 300mg, that's all. It was okay and not horrible to deal with.
Considering I get my meds free or really cheap, I felt I had nothing to complain about. I told my psychiatrist, who's a total jerk for the record what had been going on when I took this weird, big, yellow pills that looked nothing like the name brand or the other generic I had. He made me feel like some sort of alien, as if what was coming out of my mouth was mindless babble. I knew what I had been feeling, but somehow to him, I was a lier. Like many others I thought my pharmacy made a mistake.
Tomorrow or within the next few days I have another refill to pick up. I flushed the remainder of what I had down the toilet. If I receive the same thing (yellow budeprion), I'm going to just hand it back to them and say "you guys obviously need the money, more than I need this". Why take something that's makes me worse off than I normally am?!
I really didn't want to experience side-effects of coming off of it, that's why I didn't stop taking the budeprion. It made me extreme edgy, easily prone to bouts of anger, and unhappy. Feeling like there was no reason to live. I felt that I was dependent on these pills and it played a toll on my self-esteem.
I almost lost some "friends" from the handful of episodes that I had. I had a complete mental breakdown and crying wasn't enough anymore. I had to hit pillows or squeeze the closest thing to me as hard as I could. I don't know if what I'm saying is making sense to any of you reading this, but hopefully. I apologize for the long entry. Long story, short: Wellbutrin XL 300mg = Excellent! Bupropion XL 300mg = Pretty good. Buderprion XL 300mg = Unbelievably unnecessary and not worth it!
Posted by i4gotmy_sn on July 10, 2007, at 4:20:03
In reply to Re: Budeprion (Generic) vs. Wellbutrin » sdworaczyk, posted by i4gotmy_sn on July 10, 2007, at 4:12:54
Posted by Michelle Schultz on July 10, 2007, at 12:43:04
In reply to Re: Budeprion (Generic) vs. Wellbutrin » sdworaczyk, posted by i4gotmy_sn on July 10, 2007, at 4:12:54
Your story completely mirrors mine. I work for an insurance company that regularly tells people the generics are exactly the same as the RX. We know how wrong they are. No one listens to us because we have "issues" I bet if we were diabetic they would listen.
Good luck and hang in there.
> Last night was the last time I took budeprion XL 300mg and it will be the last time ever. What a joke! Unfortunately I'm financially disadvantaged at the age of 20, so I can't purchased the name brand. I had been taking Wellbutrin XL 300mg for a while now and I was fine while on it. I can even so far as to say that I was decent on bupropion 300mg. It had little to no difference. I felt like I was just not getting a full effect of 300mg, that's all. It was okay and not horrible to deal with.
>
> Considering I get my meds free or really cheap, I felt I had nothing to complain about. I told my psychiatrist, who's a total jerk for the record what had been going on when I took this weird, big, yellow pills that looked nothing like the name brand or the other generic I had. He made me feel like some sort of alien, as if what was coming out of my mouth was mindless babble. I knew what I had been feeling, but somehow to him, I was a lier. Like many others I thought my pharmacy made a mistake.
>
> Tomorrow or within the next few days I have another refill to pick up. I flushed the remainder of what I had down the toilet. If I receive the same thing (yellow budeprion), I'm going to just hand it back to them and say "you guys obviously need the money, more than I need this". Why take something that's makes me worse off than I normally am?!
>
> I really didn't want to experience side-effects of coming off of it, that's why I didn't stop taking the budeprion. It made me extreme edgy, easily prone to bouts of anger, and unhappy. Feeling like there was no reason to live. I felt that I was dependent on these pills and it played a toll on my self-esteem.
>
> I almost lost some "friends" from the handful of episodes that I had. I had a complete mental breakdown and crying wasn't enough anymore. I had to hit pillows or squeeze the closest thing to me as hard as I could. I don't know if what I'm saying is making sense to any of you reading this, but hopefully. I apologize for the long entry. Long story, short: Wellbutrin XL 300mg = Excellent! Bupropion XL 300mg = Pretty good. Buderprion XL 300mg = Unbelievably unnecessary and not worth it!
Posted by BME on July 12, 2007, at 9:37:47
In reply to Re: Budeprion XL (Generic) vs. Wellbutrin, posted by Michelle Schultz on April 24, 2007, at 11:01:48
I'm so glad it occurred to me to google Budeprion XL...I thought it was just me. It had gotten to the point where I just stopped taking it becuase there was no difference on/or off. Many thanks to each of you for posting your experiences. I jsut called the pharmacy to switch back to Wellbutrin XL (which I was on for years, but I was trying to save a few bucks). Thanks.
Posted by stargazer2 on July 17, 2007, at 20:26:08
In reply to Budeprion XL versus Bupropion HCL XL, posted by Wildflower on February 15, 2007, at 17:19:16
I just filled a prescription with the generic wellbutrin SR and got Budeprion. Why is it called Budeprion if the active ingredient is called buproprion. And how do I know these pills (yellow with the letter 'G' on one side and the number '2444'on the other side) are really buproprion when the generic manufacturor changes the name from Buproprion to Budeprion. How's that for making a situation more confusing.
I wish I read these posts before filling the prescription with the generic brand. Why is there a 'G' on the pill , what does that stand for????
I think the manuacturor is Teva (why no 'T' on the pill)...What if the pharmacist tech filled the bottle with another drug how would you know it if the pill is not identified with the name 'Buproprion', this is really upsetting to me.
We are being messed with again and again with these generics not being identical to the brand names, happened with Nardil in 2003 and people got worse, seemingly related to the new formulation.
How are we to know that the generics are as good as the brand name? Too much uncertainty surrounds the generics that I may go back and get Buproprion rather than Budeprion. Is Buproprion still available as a generic or has Budeprion replaced all the previous generics I knew as buroprion?
Stargazer
Posted by cynomom on July 18, 2007, at 19:19:15
In reply to Re: Budeprion XL versus Bupropion HCL XL, posted by stargazer2 on July 17, 2007, at 20:26:08
Well folks, some weeks ago I posted a message about taking budeprion. I took it for 3 weeks and before finding this website, thought that I was going "crazy" if you know what I mean. I was regressing and didn't know why. I decided to insist that the pharmacist give me the generic buproprion, which he did and I began to get better. I told my shrink what had happened and he put no susbstitutions on the next script for wellbutrin SR 200 mgs. I have a medicare plan and generic meds are 1 dollar for each script. When I filled my next script for the real thing it cost me only $3.10. I've been taking the name brand for about 2 weeks and boy can I tell the difference. The effects of the generic bupropion comes close to the brand name but not quite. I know everyone's body chemistry if different, but I am doing the best on the brand name Wellbutrin SR. I thought it might be all in my mind so I tried drinking a cup of coffee while taking the generics and then a few weeks later while taking the brand name. With the generics I felt like I had about 10 cups of coffee and was jittery and anxious for about 4-5 hours. With the brand name I didn't feel any side effects at all.
I don't know if anyone else has had this same experience, but for me it's the real thing or nothing.
Posted by Ladybug56 on July 19, 2007, at 11:59:33
In reply to Re: Budeprion XL versus Bupropion HCL XL, posted by stargazer2 on July 17, 2007, at 20:26:08
My generic Wellbutrin XL are large yellow oblong pills with the number 682 written on one side and blank on the other. It spells out BUDEPRION XL then underneath says (buPROPion HCI). Is this what some of you are on?
Cindy
Posted by al cann on July 30, 2007, at 9:00:35
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by smom on January 17, 2007, at 10:16:55
Hi everyone,
I am new to psycho-babble and rather than searching through all the posts on generic Budeprion vs Wellbutrin, I thought I'd ask the question. Sorry if this has been asked somewhere along this thread.
I have been taking Wellbutrin probably for about 5 or 6 years with positive results, no side effects. For the first time, I tried Budeprion and I am not happy with the results. I don't feel as I did on the Wellbutrin but most importantly I am experiencing sexual side effects such as not being able achieve an erection. Sorry for the graphic nature of this post, but I really need to know if anyone else out there has experienced anything like this. On the Wellbutrin, nothing like this ever happened.
Thanks -- AC
Posted by sheofthemoon on August 22, 2007, at 11:52:28
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by Michelle Schultz on June 8, 2007, at 5:53:51
Hi Everyone,
I used to take Budeprion XL 300mg (TEVA) until four days ago. My experience with the generic was not a pleasant one.
A summary of my own side effects: complete loss of appetite, extreme mood swings, hallucinations and heightened touch and vision (note: not better, just more intense), spacial distortion, dizziness, "zoning out", sexual dysfunction, paranoia, significantly increased desire to commit suicide, severe depression, extreme tearfulness lasting hours, alternating with a feeling of numbness. This is the short version. Everything below is an explanation of these side effects as far as how much they impacted my life. Be forewarned: it's a novel!
Within the first four days of starting Budeprion XL I had hallucinations and heightened sensory experiences of touch and sight. It takes a quarter of a page to tell the whole story but this is how my psychiatrist summed it up. This is supposed to be one of the "rare side effects" of the drug. My doctor explained that hallucinations are thought to be caused by excess dopamine in the brain, and since bupropion is a dopamine agonist, it is possible this could explain my experience. However I am now on my fourth pill of my new Bupropion XL 300mg (WATS) rx, and have not had this experience. Nor did I on the 100mg, 3x a day original formulation bupropion I took initially which was also made by Teva.
Loss of appetite is completely uncharacteristic of me. It has never happened, even when I had food poisoning, I still had the hunger signal but couldn't eat. I love food as a general rule. While taking the Budeprion, I would forget to eat, not have any hunger signal from my body at all even if I went more than a day without food. When I had my favorite foods in front of me I would feel nauseous at the thought of eating. Towards the end of the month even my morning coffee appeared disgusting to me. My doctor expressed concern because while taking bupropion it is very important to eat on a relatively consistent schedule multiple times a day to help avoid the seizure risk. I felt I could not.
Extreme mood swings while taking this medicine had me going from comfortably balanced emotionally and very productive at work (which happened four days of the month), to euphoric with very pingy nervous energy and too distractable to work at my most effective; to completely, distraughtly depressed, tearful for hours which caused very painful headaches and a feeling of physical sickness, and also the feeling of being too weighted down to move, more so than the "lead weight" symptoms of atypical depression, which under normal circumstances I can deal with effectively enough to continue on with daily activities. In this case I missed four days of work.
Spacial distortion includes not only altered depth perception but things appeared bigger, closer to me, or otherwise disproportionate to how they "should have been". That persisted off and on for the entire time I was on the medication, exactly one month. I haven't experienced it yet on my new rx.
I "zoned out" especially when starting the Budeprion XL but the side effect persisted although not as noticeably for the entire month. It was specifically noticeable when people pointed it out as they were trying to talk to me, or had to repeat what they said to me.
Sexual dysfunction included significant decrease in desire and responsiveness throughout the month, which my fiance noticed but I did not, because my attentions were focused on dealing with the other side effects and trying to find a healthy evenness.
I fought with paranoia moreso than usual. I haven't been diagnosed with clinical paranoia, it's usually so little of an issue because under normal circumstances I can think and reason my way out of it very effectively. Fighting with this consistently and nearly all the time became steadily more of an issue towards the end of the month. I am still dealing with it as the remnants of the Budeprion are leaving my body, or so I tell myself because there is no clinical proof that this is true.
The increased depression and suicidal tendencies go hand in hand and are related to the mood swings. The four days I missed work were the worst of the month, and I feel they were the cumulative result, seeing as they were the last days of that rx. I had phone sessions with a doctor three of the four days. The first day I had been in my psychiatrist's office. The last day, at which point I was hopeful that the next day I could return to work, I requested an extra session asap which would be very early the next morning, before I would return to work.
There were no genuine suicide attempts to land me in the hospital although it was suggested that I go. I have fought with ideation before, but there were times this month where I had to consistently talk my way down from it.
So that's it. That's my novel about my experience with Budeprion XL last month. I feel like I am doing better now, four days into the new rx. I guess I may see whether the pill was really the culprit or not, over time. I just thought this info was worth posting here, and I saw the article written on The People's Pharmacy website, which I know many of you wrote into. The article says that the FDA "assured them that it will analyze the drug and the reports it received." The link to this:
www.peoplespharmacy.com/editorial/generic_antidepressant_raises_questions.asp
I have researched into what could be the difference in inactive ingredients between the two generics and the brand, but with no luck. I found the inactives on Wellbutrin XL and that's it.
I hope that everybody is feeling better and moving forward much easier now, and I wish everyone the best! Thanks for your posts which helped me realize that this could be an issue!
Posted by pollyjean on September 6, 2007, at 13:16:14
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by sheofthemoon on August 22, 2007, at 11:52:28
I've been taking Wellbutrin XL 300 mg for about 5-6 years now. Initially I had the standard jittery feeling side effect along with dry mouth, and soon after that I had extreme loss of appetite and nausea. Thankfully the jitters and dry mouth went away in just a few months, though the appetite came back much more gradually. The nausea went away as soon as I was able to consistently take the pill with food. A few months ago when the generic Budeprion XL 300 mg became available my insurance automatically switched me, which I was happy about because it's so much cheaper. I didn't have any side effects so I thought everything was the same, but after about a month I had obvious symptoms of depression (which I haven't struggled with *at all* on brand, except for a brief attempt to go on the Pill for birth control -- sudden extreme depression that went away as soon as I stopped taking it). Anyway, after 2 months on Budeprion I was ready to make an appointment with the doctor. My depression isn't that extreme unless something bad happens but by this point I was just generally sad, tired, trouble sleeping, crying for no apparent reason, feeling worthless, unproductive, you know the rest. However, a switch in health insurance resulted in them putting me back on brand without me requesting it. I decided to wait and see if that made a difference before calling the doctor, and within a week I was back to normal. I've been back on brand for about 3 months now and all is normal. I had some of the jitters and dry mouth again when I went back on, but they're gone now. I can't believe Budeprion is marketed as "the same thing" as Wellbutrin, because clearly it's not! I'm glad it works for some people, though, and would love to be able to take a generic myself if it worked!
Posted by zenhussy on September 6, 2007, at 16:33:50
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by pollyjean on September 6, 2007, at 13:16:14
>>>generally sad, tired, trouble sleeping, crying for no apparent reason, feeling worthless, unproductive, you know the rest.<<<
sounds very similar to what many have gone through on this generic.
sorry you had to endure that. how fortunate to have such positive results after returning to the namebrand Wellbutrin XL 300mg. bummer you suffered a few dismal depressed months on the generic Budeprion XL 300mg. after several years of effective medications one doesn't expect a generic to be as ineffective as a sugar pill! but for many this Budeprion XL has been just that.
somewhere in this thread is a link to FDA to report such reactions to medications (assuming you're in USA). many have reported their negative experiences w/ this generic this past year(2007).
generics can vary so widely. 4 of 6 meds in our cocktail are generics and have been for at least seven years w/o incident UNTIL this particular generic Budeprion XL 300mg back in the beginning of this year. thank goodness pdoc wrote rx for 'namebrand only-medical necessity' so the ins. co and pharmacy cannot swap out to save a few dollars at the expense of a patient's health.
glad you're back to being 'you' and the depression has been taken care of with the namebrand Wellbutrin XL 300mg.
Posted by Mark in SC on September 23, 2007, at 23:01:07
In reply to Re: Budeprion (Generic) vs. Wellbutrin XL » darling, posted by darling on March 12, 2007, at 15:34:36
I just switched to Budeprion from Welbutrin because of the price savings.After I started taking Budeprion I thought that maybe I had been given something else besides Welbutrin. I have never been so irritable and agitated in my life: also am very depressed (I am not taking Welbutrin for depression anyways). I have been okay as far as getting things done though. Thank goodness someone posted a picture of what Budeprion looks like because like I said I thought the pharmacy had given me some other incorrect drug by mistake. I will definitely trash this Budeprion. I don't think its the same thing even though its supposed to be. I am also reporting what happened to my Dr, my pharmacy and the FDA site given in these postings. I hope you all do better with it than I have.
Posted by Mark in SC on September 23, 2007, at 23:05:50
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by Arlene223 on April 3, 2007, at 1:30:42
I just switched to Budeprion from Welbutrin because of the price savings.After I started taking Budeprion I thought that maybe I had been given something else besides Welbutrin. I have never been so irritable and agitated in my life: also am very depressed (I am not taking Welbutrin for depression anyways). I have been okay as far as getting things done though. Thank goodness someone posted a picture of what Budeprion looks like because like I said I thought the pharmacy had given me some other incorrect drug by mistake. I will definitely trash this Budeprion. I don't think its the same thing even though its supposed to be. I am also reporting what happened to my Dr, my pharmacy and the FDA site given in these postings. I hope you all do better with it than I have.
Posted by DharmaBum on September 24, 2007, at 20:16:47
In reply to Budeprion (Generic) vs. Wellbutrin, posted by Daniel2000 on September 30, 2004, at 7:41:28
Just to add fuel to the fire, my pdoc believes there are definite differences between Wellbutrin and the generics. She put me on 75 mg generic bupropion for two reasons: 1) we are starting out and there is no 75mg version of Wellbutrin and 2) I am using bupe as an adjunct to a reduced dose of effexor.
Her thought was that, money aside, if your sole AD is bupe, that's a good reason to opt for Wellbutrin and if you are using a sustained release version, she feels that Wellbutrin is also a superior choice.
I suspect I might end up on 150mg of Wellbutrin XL. I sure as hell will avoid the budeprion.
Posted by cynomom on October 2, 2007, at 20:44:14
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by DharmaBum on September 24, 2007, at 20:16:47
I took budeprion a few months back and had devastating side effects. I have been taking brand name wellbutrin for a few months now and feel great. Our bodies cannot be fooled. And it is not psychosomatic. Talk to your dr. if you have any problems with it. Some people can take it with no problem, but I couldn't as well as many others on this sight.
Posted by CaveMan on October 30, 2007, at 18:15:18
In reply to Re: Budeprion (Generic) vs. Wellbutrin » sld68, posted by darling on May 1, 2007, at 10:43:01
Ok, my insurance company switched me from Wellbutrin XL to the generic version without telling me. When the pharmacist told me it was over $100 dollars, I thought there was a mistake. No mistake here. Both my therapist and I have been sending letters and filling out forms, but I just recieved a final "NO" from AvMed.
The generic version made me feel more depressed than ever with horrible mood swings and bursts of rage. I didn't want to go out or see my friends. All I wanted was to stay home with the doors closed, the lights out, and feel sorry for myself. When I did decide to meet some friends, I felt completely out of place. It was like I was seeing myself from the outside and just wanting to run. I could hardly maintain a conversation. Bottom line. There is a huge difference between brand vs generic budiprion.
Jeff
Posted by stargazer2 on October 31, 2007, at 8:31:50
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by CaveMan on October 30, 2007, at 18:15:18
This issue has been brought to the FDA's attention becasue of so many complaints. They are looking into it. Many people have said it is not working as well as Buproprion did.
This happened with Nardil as well but since there are not as many people on Nardil, so I think it has fallen on deaf ears.
The pharmaceutical companies have gottn away from testing the generic drugs since the generics supposedly contain the same active ingredients as the brand name. But what is not the same are some of the 'non-active" ingredients which affect thing like the absorption time, etc.
It's not happening just with psych meds either. People on BP meds are finding their BP is not being controlled with some of the generics.
It's bad enough when it happens to one generic but many brands have multiple generics.
How many people out there are taking generics and suffering from them and don't even know it?
It sounds like a major blunder on the part of the FDA....They don't have enough staff as it is to test all the new 'brand' name meds, let alone,all of the generic forms of the brand.
Wellbutrin is the brand, Bupropprion is the generic, so what is Budeprion, the generic of the generic? It's mind boggling and the impact of all of this is more patients who have been stabalized being destabalized. A real health care crisis if you ask me.
Stargazer
Posted by pandawat on November 29, 2007, at 11:08:26
In reply to Budeprion (Generic) vs. Wellbutrin, posted by Daniel2000 on September 30, 2004, at 7:41:28
I've been on Wellbutrin for years, and just tried Budeprion this past week. My opinion is that Budeprion sucks elephant *#@*!@#!!! Whoever tried to pass it off as Wellbutrin should be shot. I've never been this close to suicide in my life. It's as if I just stopped taking Wellbutrin cold turkey. Also stopped smoking a long time ago, but am craving cigarettes again now.
Posted by doylethug on December 5, 2007, at 17:52:05
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by Dubster on September 5, 2005, at 21:28:05
I recently took budeprion and experieced nausea for about 2 weeks. Then the prescription ran out and now I'm on buprion XL. When I take them in the morning I feel really angry and confused. Has anyone experienced this and if so did it subside?
Posted by sdworaczyk on December 6, 2007, at 8:52:06
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by Dubster on September 5, 2005, at 21:28:05
My son and I started having boughts of rage or being set off by the smallest thing and castrophizing the situation on the name brand Wellbutrin XL after a few months, (however I had such horrible affects on the generic I wanted to just die for the brief 2 weeks I took it). We are both still taking the Wellbutrin XL, however our doctor added 10mg of Lexapro daily to it and we have both had excellent results, I feel better than I have in years with the added Lexapro. I hope this helps.
Posted by 30years on December 28, 2007, at 14:24:08
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by sdworaczyk on December 6, 2007, at 8:52:06
I honestly don't understand the complaints between the brand-name and the generics. I've been on anti-depressents for the worst kind of depression for about 30 years now and have never noticed any difference going from brand-name to generics. Generics are the identical chemical composition as the brand-names (such as Wellbutrin).
The New England Journal of Medicine reports that "Generic-drug manufacturers must establish bioequivalence to the active ingredients of the original drug and demonstrate adherence to FDA-approved manufacturing processes."
I've been switched from Wellbutrin XL to Budeprion XL and now to Bupropion HCL--all contiain the chemical makeup of "bupropion HCL." I've never had new side effects or noticed any difference in efficaciousness. Same is true for all the generics I've been on the last 30 years.
The ONLY thing that might make a difference is if the XL (extended release) process is different in the differing generics versus the brand-name drug--i.e., if the extended release of the drug is somehow not equivalent over time. Seems the FDA oversight of the manufacturing process should also eliminate any problems there as well.
Perhaps Dr-Bob has some insight.
Posted by mom2 on January 12, 2008, at 15:34:15
In reply to Re: Budeprion (Generic) vs. Wellbutrin » Arlene223, posted by kingcolon on April 22, 2007, at 12:51:23
I got my Wellbutrin XL filled yesterday, and also was switched to the generic Budeprion XL without notice from the pharmacy. I am curious if there is anyone that has taken the Budeprion XL without any problems? I am nervous about taking a generic for depression when the brand works so well. Thanks!
Posted by Mclscotts on January 12, 2008, at 15:41:18
In reply to Re: Budeprion (Generic) vs. Wellbutrin, posted by mom2 on January 12, 2008, at 15:34:15
I HAVE USED BUDEPRION XL FOR ALMOST A YEAR NOW AND I HAVE HAD NO PROBLEMS WITH IT, I TRIED THE WELLBUTRIN XL NAME BRAND FOR A MONTH AND THEN SWITCHED TO THE GENERIC. I REALLY DON'T SEE ANY DIFFERENCE AT ALL AND I DON'T UNDERSTAND WHY SO MANY PEOPLE ARE COMPLAINING ABOUT IT.
> I got my Wellbutrin XL filled yesterday, and also was switched to the generic Budeprion XL without notice from the pharmacy. I am curious if there is anyone that has taken the Budeprion XL without any problems? I am nervous about taking a generic for depression when the brand works so well. Thanks!
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Script revised: February 4, 2008
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