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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by jhj on August 22, 2007, at 3:55:03
Hi,After trying many drugs for social phobia,i asked my pdoc to try Nardil.But,Unfortunately,no MAOI is approved in India(I am from India by the way).He said that first he would arrange moclobemide which is approved in our neighbouring countries and if it does not work then he will arrange Nardil or Pernate from somewhere.Is moclobemide as effective as Nardil in social phobia? Anybody has any idea? Thanks
Posted by Jamal Spelling on August 22, 2007, at 6:11:59
In reply to moclobemide,Phenelzine(Nardil) comparision?, posted by jhj on August 22, 2007, at 3:55:03
Since moclobemide is not approved in the US, probably few people on this board will have had much exposure to it.
My own psychiatrist was actually involved in a research study on moclobemide. She told me she thought it was pretty lame as a monotherapy treatment, weaker than SSRIs for example.
Jamal
Posted by Quintal on August 22, 2007, at 10:56:26
In reply to moclobemide,Phenelzine(Nardil) comparision?, posted by jhj on August 22, 2007, at 3:55:03
I took moclobemide for six months at the maximum dose back in 2003. It was utterly useless for me. The only effect I noticed was insomnia and a bit of agitation at the beginning. I haven't read of a single long-term success story with this drug, though there may well be one somewhere.
Dr. Ken Gillman is a (now retired) psychopharmacologist and psychiatrist, and he used the older non-selective, irreversible MAOIs to treat patients for most of his career; becasue he found them to be the most reliably effective antidepressants. This is his opinion of moclobemide:
____________________________________________________Many clinicians are finding that the new MAOI (or 'RIMA'), moclobemide, is not an effective antidepressant; this view is substantiated by some clinical trials which constitute evidence that moclobemide is no more effective than placebo. In my opinion it is totally ineffective, I gave up using it years, no decades, ago. The minimal effect it has on neurotransmitters is detailed in my recent review.
http://www.psychotropical.com/maois_full.shtml
__________________________________________________I'd recommend reading the full website. There are plenty of references to studies that you could offer your psychiatrist in support of trying phenelzine before moclobemide. If your psychiatrist is one of the paternalistic types that demands obedience to his commands, and puts that above your wellness, then I suppose you will just have to give moclobemide a shot. There are always exceptions and it may work for you of course.
Q
Posted by jhj on August 23, 2007, at 2:09:54
In reply to Re: moclobemide,Phenelzine(Nardil) comparision? » jhj, posted by Quintal on August 22, 2007, at 10:56:26
Hi,
I have also tried to find some studies showing efficacy of moclobemide in social phobia or depression.Well,my psychiatrist is just like what you have suggested and did not want to use MAOI at all but i told him clearly that i would like to try MAOI.Then,he said because moclobemide is available in our neighbouring countries,we should try it first.He says he will have to get phenelzine from USA and it will be difficult.Can you please tell me how i can get any drug from USA in India.Once,i know it i can tell him that we can get the drug in India and so he can not give me any excuse for not giving phenelzine.Thanks.
Posted by Quintal on August 24, 2007, at 0:25:01
In reply to Re: moclobemide,Phenelzine(Nardil) comparision?, posted by jhj on August 23, 2007, at 2:09:54
I've contacted the manufacturer of Nardil in the UK, Concord, on your behalf. I'll report back if/when I get a response. I'll see what I can do with Pfizer, the US manufacturer. Is there any reason why you must import from the US? I'm asking because as you may already know, Pfizer changed the formulation of their Nardil tablets back in 2003 and many users have complained that the new formulation is less effective than the original, allegedly due to the loss of a hard-shell coating that protects the active chemical from stomach acid. Nardil is manufactured by a different company in the UK, and Australia too I think. Their formulation is slightly different from the original Pfizer one, but still retains the hard-shell coating, and hopefully better efficacy. I'd recommend importing one of these brands over the re-formulated Pfizer ones if you can.
Q
Posted by jhj on August 24, 2007, at 1:19:07
In reply to Re: moclobemide,Phenelzine(Nardil) comparision? » jhj, posted by Quintal on August 24, 2007, at 0:25:01
Hi Quintal,
So sweet of you.There is no specific reason for importing from US.Actually i do not know where else phenelzine is available.I do not know anything about how to get it from outside.I am completely blind on that.My pdoc has told me that he will need to get it from US perhaps because he is not interested in giving me irrevarsible MAOI and that is why he gave me wrong information.Please do not waste much of your time in investigating it.Now i know that i can get it from other places as well as informed by you and that phenelzine is likely to be more effective then moclobemide,i think i will give my pdoctor serious blast.The things is that most Indians do not know about mental illness and out of those who know most of them do not try to research their options and that is why these psychiatrist give them what they want to.Thanks anyway.I appreciate it.
Posted by Quintal on August 24, 2007, at 1:36:44
In reply to Re: moclobemide,Phenelzine(Nardil) comparision?, posted by jhj on August 24, 2007, at 1:19:07
Oh well, I just sent a second email because the first was returned with a note telling me that Concord is in the process of changing its name to Archimedes Pharma, and their customer service rep has left the company. I managed to locate the new one though. It's no problem - I'm curious to see if the manufacturer will sell direct to a physician, or if they can recommend a pharmacy or something.
http://www.concordpharma.com/Q
Posted by Quintal on August 30, 2007, at 13:55:38
In reply to Re: moclobemide,Phenelzine(Nardil) comparision? » jhj, posted by Quintal on August 24, 2007, at 1:36:44
I got this yesterday:
__________________________________________________Dear Quintal,
thank you for your enquiry regarding Nardil. I am passing your enquiry over to my commercial director ,Chris Bubb, who
can better deal with the supply of Nardil on a named patient basis. At the moment Chris is on annual leave, however he will
be returning to work on the 4th September and once he has caught his breath he will answer your enquiry in a more satisfactory
manner.
Kind Regards
Simon Collins
Country Manager (UK and RoI)
Archimedes Pharma.
__________________________________________________Q
Posted by jhj on September 1, 2007, at 8:49:17
In reply to Re: moclobemide,Phenelzine(Nardil) comparision?, posted by Quintal on August 30, 2007, at 13:55:38
Thanks for your efforts.I really appreciate them.
Posted by Lebrada on September 16, 2007, at 10:33:21
In reply to moclobemide,Phenelzine(Nardil) comparision?, posted by jhj on August 22, 2007, at 3:55:03
>
> Hi,
>
> After trying many drugs for social phobia,i asked my pdoc to try Nardil.But,Unfortunately,no MAOI is approved in India.Hi, I live in New Zealand - prior to the govt reinstating NARDIL (completely subsidized) I got it from the UK;
www.XXX.com
Bai, don't think about it - just (order)/do it!
P.S. I'm Euro/Indian just returned from six months in India (delhi, Mumbai, Chandigah, Ludhiana, Haryana, Goa, Bangalore...
Posted by Lebrada on September 16, 2007, at 10:40:14
In reply to Re: moclobemide,Phenelzine(Nardil) comparision?, posted by jhj on August 23, 2007, at 2:09:54
Can you please tell me how i can get any drug from USA in India...
Bai, See prior:
www.XXX.com
- bypass your Doc and just order it yourself...OR
If you prefer you can mail me your script I wud be happy to order it here from New Zealand for you and mail it - let me know.Once you try Nardil - you'll find that there's no going back;)
Posted by Deputy Racer on September 17, 2007, at 2:47:30
In reply to Re: moclobemide,Phenelzine(Nardil) comparision?, posted by Lebrada on September 16, 2007, at 10:40:14
> - bypass your Doc and just order it yourself...OR
> If you prefer you can mail me your script I wud be happy to order it here from New Zealand for you and mail it - let me know.
>Please do not post information about obtaining drugs without a prescription.
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