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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by mission7 on August 16, 2007, at 21:37:55
I read info that:
-Effexor works on serotonin receptors at lower doses and norepinephrine NT at higher doses.
-Webbutrin works on norepinephrine.
- Prozac works on serotonin.When I took Prozac all I thought about was suicide.
When I took Wellbutrin I became enraged, almost violent.
When I took Effexor, at low doses, it worked awesome. But, when I tried to up the does I became enraged.That would lead me to conclude a few things:
“Working on” norepinephrine enrages me.
For whatever reason Prozac just wasn’t my thing.
I benefit from suppressing serotonin re-uptake, or “working on serotonin” because Effexor helps me so much. (8yrs)My problem: Over time I think that Effexor has lost some of it’s power to help, so I’d like to increase the dose, thereby increasing the “work done” on serotonin. . But, I can’t without it messing with norepinephrine, which will make me angry.
Does anyone have any suggestions? (Yes, I am going to see my doctor next week, but I would like to have done my homework before doing so.)
Posted by Racer on August 16, 2007, at 22:56:38
In reply to I take Effexor and am confused about something?, posted by mission7 on August 16, 2007, at 21:37:55
It would be nice if it were as simple as "Prozac works on serotonin, Wellbutrin works on norepinephrine, thus..." It isn't that simple though.
While SSRIs do target serotonin, they're not so precise as to target *only* serotonin -- despite that "Selective" in their name. In some cases, even the binders or fillers will have effects on you. That being the case, it's worth trying the other SSRIs, despite Prozac not working for you. You already know that you had some suicidal ideation while on Prozac, so you'd want to watch out for that on other SSRIs, but they won't necessarily have the same sort of effect on you.
Otherwise, it's always trial and error.
Good luck.
Posted by Mission7 on August 17, 2007, at 12:02:18
In reply to Re: I take Effexor and am confused about something, posted by Racer on August 16, 2007, at 22:56:38
This board seem pretty knowledgeable...
I would like to increasing my Effexor dosage, but that really makes me angry. Does anyone have any suggestions at to what I could I spike it with?
This is the end of the thread.
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