Psycho-Babble Medication Thread 760318

Shown: posts 1 to 25 of 32. This is the beginning of the thread.

 

Advice from Parnate users please..

Posted by sophia04 on May 30, 2007, at 0:35:34

I am embarking on my 8th week of Parnate, but have only been at 60 mg for the last 1.5 weeks. I have found the drug to be exceedingly difficult to adjust to and so it's taken me kind of long to ramp up to my therapeutic dose. I feel as though I'm just now getting acclimated to the side effects - but am still contending with untreatable daytime fatigue and insomnia - despite the fact that I've tried lunesta and lorazepam to sleep. Problem is, I'm not sure if I'm receiving any antidepressant effects. Do you think I should hold on longer or move on at this point? There have been a handful of fleeting moments in the last 7 weeks where I thought, "maybe..?" but now I'm not so sure. I've tried nearly every med and this was kind of a last hope for me. Any thoughts?

Thank you.

 

Re: Advice from Parnate users please..

Posted by F00TBALL on May 30, 2007, at 1:43:42

In reply to Advice from Parnate users please.., posted by sophia04 on May 30, 2007, at 0:35:34

I'd stick with it a couple more weeks and then maybe switch to Nardil if you're yet to try that.

For your daytime fatigue, try Provigil. It really works wonders and it's perfectly safe with MAOIs.

And for insomnia, have you tried Seroquel? I went through several other drugs with little success before trying Seroquel. Now I sleep better then I have in years.

 

Re: Advice from Parnate users please.. » F00TBALL

Posted by Phillipa on May 30, 2007, at 11:19:29

In reply to Re: Advice from Parnate users please.., posted by F00TBALL on May 30, 2007, at 1:43:42

So you like the seroquel for sleep have you tried a benzo or lunesta? Love Phillipa

 

Re: Advice from Parnate users please..Football

Posted by sophia04 on May 30, 2007, at 23:24:04

In reply to Re: Advice from Parnate users please.., posted by F00TBALL on May 30, 2007, at 1:43:42

> I'd stick with it a couple more weeks and then maybe switch to Nardil if you're yet to try that.
>
> For your daytime fatigue, try Provigil. It really works wonders and it's perfectly safe with MAOIs.
>
> And for insomnia, have you tried Seroquel? I went through several other drugs with little success before trying Seroquel. Now I sleep better then I have in years.

Thanks for the response. I really appreciate it. Have you ever tried just Provigil + taking your entire parnate dose before 3:00 pm? Currently i take the bulk of mine after then because it makes me so tired and I feel like insomnia is the lesser of two evils - even though I still have quite a bit of fatigue once I start my dose at noon (10 mg),
4:00 (10 mg),
7:00(10 mg)
10:00 pm (30mg)

I'd really like to do either a stimulant or a sleep aid, and ideally not both, but that may be the case is parnate's AD properties start to kick in - which I'm still hoping they will. Any info you can give me (everyone!) is GREATLY appreciated!

 

Re: Advice from Parnate users please.. » sophia04

Posted by Jedi on May 31, 2007, at 2:49:54

In reply to Advice from Parnate users please.., posted by sophia04 on May 30, 2007, at 0:35:34

Hi Sophia,
I'm on 80mg of Parnate and it has taken three months for my daytime fatigue to lessen to a tolerable level. For two months I was taking two hour naps in the late afternoon when I got off work. So far, for me, Parnate has not been as efficacious as Nardil for my atypical depression or social anxiety. However, the weight gain side effect of Nardil is not present for me on Parnate. Baring a complete relapse, I'm going to stick it out for a couple of more months. I was really beginning to wonder if the daytime somnolence would ever go away; it just takes a lot of time. I take 25mg of Seroquel for the medication induced insomnia.
Good Luck,
Jedi

 

Re: Advice from Parnate users please..

Posted by malcolm664 on May 31, 2007, at 13:25:08

In reply to Re: Advice from Parnate users please.. » sophia04, posted by Jedi on May 31, 2007, at 2:49:54

> Hi Sophia,
> I'm on 80mg of Parnate and it has taken three months for my daytime fatigue to lessen to a tolerable level. For two months I was taking two hour naps in the late afternoon when I got off work. So far, for me, Parnate has not been as efficacious as Nardil for my atypical depression or social anxiety. However, the weight gain side effect of Nardil is not present for me on Parnate. Baring a complete relapse, I'm going to stick it out for a couple of more months. I was really beginning to wonder if the daytime somnolence would ever go away; it just takes a lot of time. I take 25mg of Seroquel for the medication induced insomnia.
> Good Luck,
> Jedi
>

I'm on 60 mgs of Parnate, and somehow just this week (I think) that the med finally beginning to work. After suffering several weeks of almost intolerable anxiety, I'm finding that the anxiety is all of a sudden much less. I'm still not experiencing any euphoria like I did on Nardil, however.

I know that the change seems so sudden that I almost have a hard time believing it. Could it be my imagination?

Re: being on 80 mgs, my doc refuses to go above 60; he says that he doesn't want to do anything that would harm me. Of course, I appreciate that (and he is a well known psychopharmacologist in Wash, DC; I had to wait almost 2 months before I got an initial appointment to see him), so ultimately I'll have to trust his judgement, but at the same time I'm very curious to see whether the higher dose will replicate the wonderful effect of Nardil (alas, it was very short-lived).

Jedi: I'm curious, did you try Provigil for the drowsinesss? That's another med my doc refuses to prescribe while on an MAOI (he doesn't want me on any stimulants of any kind - not even coffee). Of course, I've been taking 1000 mg of caffeine tabs - against his wishes - b/c otherwise I wouldn't be able to function at all (and even WITH 1000 mgs of caffeine tabs, I STILL get drowsy).

But I've been reading about several members of this board being on an MAOI and Provigil and there have apparently been no probs, that I'm wondering if in this case he is being a bit too cautious.

Given that Provigil is a completely different kind of stimulant than the others (Ritalin, Dexosyn, Concerta--all worked great at keeping me awake, but none really did anything for my non-verbal learning disorder), I'm just curious if anyone knows what the potential danger is of Provigil and MAOI's?

Malcolm

 

Re: Advice from Parnate users please..Malcolm

Posted by sophia04 on May 31, 2007, at 20:50:30

In reply to Re: Advice from Parnate users please.., posted by malcolm664 on May 31, 2007, at 13:25:08

Thank you Malcolm,

How long have you been taking parnate? How long have you been on 60mg? Has it taken you a relatively long time to reach that dose? I too am on 60mg and have been for a couple weeks. Wondering IF i will have a breakthough.

Thanks,
Sophia

 

Re: Advice from Parnate users please..Malcolm

Posted by malcolm664 on May 31, 2007, at 23:03:59

In reply to Re: Advice from Parnate users please..Malcolm, posted by sophia04 on May 31, 2007, at 20:50:30

> Thank you Malcolm,
>
> How long have you been taking parnate? How long have you been on 60mg? Has it taken you a relatively long time to reach that dose? I too am on 60mg and have been for a couple weeks. Wondering IF i will have a breakthough.
>
> Thanks,
> Sophia

I've been on Parnate since around 23rd of April but first really noticed the effect a couple of days ago. I've been keeping a detailed diary but unfortunately, I didn't write down how much I started with (I THINK 30 mgs, so apparently my diary isn't detailed enough) but doubled the dose (to 60 mgs) about a week ago and that's when I noticed the difference. I see my doc tomorrow and will ask him if he can tell me what I started out with and when exactly I moved it up (again, I THINK it was about a week ago).

I remember calling him to tell him that I wasn't really feeling better at the dose that I was on, so that's when he had me increase it...to 60 mgs. That much I know is accurate.

In fact, just this evening I was talking with my brother and telling him how I thought that the med was finally working. I defintitely feel much...calmer...that's the only way to describe it. And the anxiety up to this point was pretty crushing.

I can only hope and wish that you experience a similar reaction, but with all psych med, reactions are notoriously individual.

I'd say "hang in there", but I know that phrases like that are meaningless when people say things like that to me.

What I will say is that I know exactly what you're going through, so if that's any comfort...Of course, I'm being a bit presumptuous by comparing our situations. For all I know yours could be much, much worse than mine.

BTW, I'm also on 1 mg xanax XR (taken when I wake up) and .75 mgs of Klonopin (taken right before bedtime).

I'll let you know what I find out from my doc after our appointment tomorrow and post a follow-up message to this BB...or you can also e-mail me at msaldanha@verizon.net.

Malcolm

 

Re: Advice from Parnate users please..Malcolm

Posted by malcolm664 on June 1, 2007, at 19:44:31

In reply to Re: Advice from Parnate users please..Malcolm, posted by malcolm664 on May 31, 2007, at 23:03:59

> > Thank you Malcolm,
> >
> > How long have you been taking parnate? How long have you been on 60mg? Has it taken you a relatively long time to reach that dose? I too am on 60mg and have been for a couple weeks. Wondering IF i will have a breakthough.
> >
> > Thanks,
> > Sophia
>
> I've been on Parnate since around 23rd of April but first really noticed the effect a couple of days ago. I've been keeping a detailed diary but unfortunately, I didn't write down how much I started with (I THINK 30 mgs, so apparently my diary isn't detailed enough) but doubled the dose (to 60 mgs) about a week ago and that's when I noticed the difference. I see my doc tomorrow and will ask him if he can tell me what I started out with and when exactly I moved it up (again, I THINK it was about a week ago).
>
> I remember calling him to tell him that I wasn't really feeling better at the dose that I was on, so that's when he had me increase it...to 60 mgs. That much I know is accurate.
>
> In fact, just this evening I was talking with my brother and telling him how I thought that the med was finally working. I defintitely feel much...calmer...that's the only way to describe it. And the anxiety up to this point was pretty crushing.
>
> I can only hope and wish that you experience a similar reaction, but with all psych med, reactions are notoriously individual.
>
> I'd say "hang in there", but I know that phrases like that are meaningless when people say things like that to me.
>
> What I will say is that I know exactly what you're going through, so if that's any comfort...Of course, I'm being a bit presumptuous by comparing our situations. For all I know yours could be much, much worse than mine.
>
> BTW, I'm also on 1 mg xanax XR (taken when I wake up) and .75 mgs of Klonopin (taken right before bedtime).
>
> I'll let you know what I find out from my doc after our appointment tomorrow and post a follow-up message to this BB...or you can also e-mail me at msaldanha@verizon.net.
>
> Malcolm
>
>

Well, I saw my doc today. He definitely doesn't think that it's a fluke that I'm feeling better: it's definitely due to the Parnate. So for now, he's got me at 60 mgs (until I see him again in 2 weeks). He also told me to stop taking the Xanax altogether and prescribed Ambien to help with the sleep. He said that Ambien (unlike other sleep meds) clears your system in the mornings, so there's no residual drowsiness the next day.

As far as dosages, I stared on 30, went up to 40 then slowly up to 60 mgs (of the Parnate, that is).

He's also more hopeful that the Parnate will last long-term. He said that what happened with the Nardil a year ago (I was seeing another doc for meds at the time) was that I experienced such a hypermanic over-reaction that there was no way it could be sustained. But given (at least so far) that I haven't lapsed into euphoria, the chances that the med will continue to work are very good.

Of course, even with a doc as experienced as he is, he can't guarantee me anything. But as of today, I'm much more hopeful about my future (and immediately about the internship which I start a week from this Monday than I was a week ago).

So for everyone who took the time to respond over the last several weeks to my incessant med-related questions (many of them probably repetitive), I just want to say: Thanks!!

I'll still keep posting here and if anyone has any questions, please feel free to e-mail me: msaldanha@verizon.net. Just put "Psyhobabble question" in the subject line so I don't confuse it with spam. That way I know that it's another poster from this bulletin board and I'll try and respond as quickly as I can.

I wish everyone the best and I of all people of course know very well what everyone is or has gone through.

Regards-
Malcolm

 

Re: Parnate users dose time/provigil..Malcolm

Posted by sophia04 on June 1, 2007, at 20:45:30

In reply to Re: Advice from Parnate users please..Malcolm, posted by malcolm664 on June 1, 2007, at 19:44:31

Malcom, + friends

That's great news!! I had the best day today that I have had in weeks - presumably, I think, because I got more than 3 hours of sleep. I have essentially been getting NO sleep despite the fact that I've dabbled w/ Lunesta, Lorazepam + Benadryl. I didn't work today and was able to sleep until noon -despite the fact that it took til 3:00 am on 1.5mg of lorazepam.

Also, my doc is in France til mid June and has never prescribed Parnate before. I'm getting all of my education right here on psycho-babble (thank you!). I think I want to start taking the bulk of the meds early in the day and try provigil and hopefully won't need a sleep aid. What do you think?

thanks again,

Sophia

 

Re: Advice from Parnate users please..football

Posted by sophia04 on June 1, 2007, at 20:49:54

In reply to Re: Advice from Parnate users please.., posted by F00TBALL on May 30, 2007, at 1:43:42

Has anyone tried to take the bulk of their parnate early, say by 2:00 pm + provigil to avoid the insomnia and forgo the sleep aid?

Thanks,
Sophia

 

Re: Advice from Parnate users please..football

Posted by malcolm664 on June 1, 2007, at 23:15:36

In reply to Re: Advice from Parnate users please..football, posted by sophia04 on June 1, 2007, at 20:49:54

> Has anyone tried to take the bulk of their parnate early, say by 2:00 pm + provigil to avoid the insomnia and forgo the sleep aid?
>
> Thanks,
> Sophia

I started out taking the Parnate in divided does, the first when I woke up and then the second dose around mid-day, but the exhaustion really got to me. So what Dr. Vittone suggested I do was to take divided doses in the evening, say 30 mgs around 6 pm and then the final 30 mgs right before bed. I was skeptical, b/c of the insomnia, but slowly it's becoming less and less of a problem.

So I've given up the Xanax XR although for now am still taking .75 mgs of the Klonopin, plus the Ambien. It's about 12 midnight right now and I'm about to hit the sack.

I'll post another message tomorrow about my sleep.

Malcolm

BTW, I asked him again about prescribing Provigil and he says that there's anecdotal evidence that combining stimulants with MAOI's is dangerous. I still think that he's over-reacting, but he's the doc and I sure as hell can't write myself a script for Provigil myself. And he seems to be a really competent physician, so I don't think that I ought to do anything against his wishes.

Malcolm

 

Re: Advice from Parnate users please..football

Posted by malcolm664 on June 2, 2007, at 11:58:40

In reply to Re: Advice from Parnate users please..football, posted by malcolm664 on June 1, 2007, at 23:15:36

> > Has anyone tried to take the bulk of their parnate early, say by 2:00 pm + provigil to avoid the insomnia and forgo the sleep aid?
> >
> > Thanks,
> > Sophia
>
> I started out taking the Parnate in divided does, the first when I woke up and then the second dose around mid-day, but the exhaustion really got to me. So what Dr. Vittone suggested I do was to take divided doses in the evening, say 30 mgs around 6 pm and then the final 30 mgs right before bed. I was skeptical, b/c of the insomnia, but slowly it's becoming less and less of a problem.
>
> So I've given up the Xanax XR although for now am still taking .75 mgs of the Klonopin, plus the Ambien. It's about 12 midnight right now and I'm about to hit the sack.
>
> I'll post another message tomorrow about my sleep.
>
> Malcolm
>
> BTW, I asked him again about prescribing Provigil and he says that there's anecdotal evidence that combining stimulants with MAOI's is dangerous. I still think that he's over-reacting, but he's the doc and I sure as hell can't write myself a script for Provigil myself. And he seems to be a really competent physician, so I don't think that I ought to do anything against his wishes.
>
> Malcolm
>
>

Well it's close to 1 pm on Sun afternoon and I woke up about a hour ago, so I'd say that I slept really great (in fact, too well); I initially woke up at around 8:30 am, but then fell right back to sleep; so the Ambien must be working.

I'm taking 12.5 mgs.

And I had no problems actually falling asleep. Of course, it's only one night, but I think I'll try breaking the pill in half tonight and see what happens. It could also be that I've been so deprived of a really great night's sleep ever since starting the Parnate, that the Ambien just allowed me to just catch up.

I just hope that waking up in the AM will not be a problem in the future while on Ambien. Nothing's worse than getting to work late.

Either way, it feels great!

best-
Malcolm

 

Re: Advice from Parnate users please..football » sophia04

Posted by OzLand on June 7, 2007, at 19:32:48

In reply to Re: Advice from Parnate users please..football, posted by sophia04 on June 1, 2007, at 20:49:54

I take 20 mg. of Parnate in the morning and am at the point of taking 10 mg. at noon and/or before 2 p.m. I am alternating now with taking 20 mg. at noon with 10 mg. everyother day. I can't take it after that time of the day or I will be up all night. I have Seroquel to take at night too if needed, but I would rather not, and this is why I take all of my Parnate before 2 p.m.

 

Re: Advice from Parnate users please..

Posted by sophia04 on June 8, 2007, at 2:31:10

In reply to Re: Advice from Parnate users please..football, posted by malcolm664 on June 1, 2007, at 23:15:36

I just don't think I can take Parnate anymore. It's been 9 weeks now - almost 3 on 60 mgs and I still am skeptical of any antidepressant effect. I'm drinking too much coffee - despite the fact that I haven't touched it for 10 years because of anxiety - but I'm so wasted from the resulting insomnia (ativan is working ok) and daytime fatigue. My dizzy/near fainting spells are periodically returning. I really don't want to "throw the baby out with the bathwater" because I feel like I've just endured 9 weeks of hell, but I think I need to accept that Parnate - the "gold standard" - is just another bust for this treatment-resistant gal. Any thoughts?

Sophia

 

Re: Advice from Parnate users please.. » sophia04

Posted by OzLand on June 11, 2007, at 22:29:41

In reply to Re: Advice from Parnate users please.., posted by sophia04 on June 8, 2007, at 2:31:10

I don't know what to say for sure. Sometimes it takes longer to work. Years ago it took at least a month or more to really start working for me. I took Mellaril at night for sleep, not something advisable anymore. Now I have a low dose of Seroquel if I need it for sleep. I am now at 40 mg., and I don't want to go higher. I think my therapy with my new therapist will help more than increasing the Parnate. I have not found any other antidepressant that works, and against my better judgment I did ECT. It helped me be less depressed before I quit doing it because of noting bad side effects and memory problems. I paid a price for doing ECT, and so I am not happy about that. Try giving the Parnate more time. Maybe you are on too much, and you were not given enough time to see if it would start to work at a lower dose. I would wonder. Doctors like to up things after a couple of weeks, and then up them again after another few weeks, etc. Maybe it is time to see if it will work by not continuing to up it?????

 

Re: Advice from Parnate users please..

Posted by Honore on June 12, 2007, at 0:31:31

In reply to Re: Advice from Parnate users please.. » sophia04, posted by OzLand on June 11, 2007, at 22:29:41

I had terrible daytime sleepiness on parnate-- which sounds contradictory, but I've found from reading here that it's not totally unknown either. Others have reported that response.

I kept taking it for several years, until another factor forced me to stop== because it helped with the depression, even though I was semi-conscious for large periods of the day, every day. I also tended to need to sleep frequently-- I literally couldn't stay awake.

But I'm glad to be off-- I think MAOIs are the only ADs that work for me, and Emsam doesn't have the same sleep effects.

Honore

 

Re: Advice from Parnate users please.. » sophia04

Posted by malcolm664 on June 12, 2007, at 4:58:44

In reply to Re: Advice from Parnate users please.., posted by sophia04 on June 8, 2007, at 2:31:10

Well I wish I knew what to say; I started taking it towards the end of April and first noticed the AD effects about two weeks ago, so I would think that you should be feeling something by now.

And I'm also on 60 mgs. Do you supplement with Klonopin or Xanax XR? I'm not saying that that would definitely help, but that's what I've been doing since I started the Parnate and perhaps it's the combination that helps.

It's obviously time for you to re-evaluate the Parnate with your pdoc, if you haven't done so already.

Best-
Malcolm

> I just don't think I can take Parnate anymore. It's been 9 weeks now - almost 3 on 60 mgs and I still am skeptical of any antidepressant effect. I'm drinking too much coffee - despite the fact that I haven't touched it for 10 years because of anxiety - but I'm so wasted from the resulting insomnia (ativan is working ok) and daytime fatigue. My dizzy/near fainting spells are periodically returning. I really don't want to "throw the baby out with the bathwater" because I feel like I've just endured 9 weeks of hell, but I think I need to accept that Parnate - the "gold standard" - is just another bust for this treatment-resistant gal. Any thoughts?
>
> Sophia

 

Re: Advice from Parnate users please..

Posted by sophia04 on June 13, 2007, at 0:38:00

In reply to Re: Advice from Parnate users please.. » sophia04, posted by malcolm664 on June 12, 2007, at 4:58:44

Thanks Malcom,
I did have an appointment finally w/ my doc and we decided to adjust the dose time - the daytime fatigue is so impactful to my work schedule and quality of life. I'm currently taking 30mg at 7:00pm and the other 30 mg at 10:00. I also (just last night) started taking 25 mg of Seroquel. Would you believe I still had insomnia and had to take ativan during the night on top of that?! Parnate's remedy-resistant insomnia is totally surreal. We shall see what happens tonight.
I'll continue to keep you all posted. Thanks!!

 

Re: Advice from Parnate users please.. » sophia04

Posted by malcolm664 on June 13, 2007, at 20:07:36

In reply to Re: Advice from Parnate users please.., posted by sophia04 on June 13, 2007, at 0:38:00

> Thanks Malcom,
> I did have an appointment finally w/ my doc and we decided to adjust the dose time - the daytime fatigue is so impactful to my work schedule and quality of life. I'm currently taking 30mg at 7:00pm and the other 30 mg at 10:00. I also (just last night) started taking 25 mg of Seroquel. Would you believe I still had insomnia and had to take ativan during the night on top of that?! Parnate's remedy-resistant insomnia is totally surreal. We shall see what happens tonight.
> I'll continue to keep you all posted. Thanks!!
>

What's Seroquel like? I've asked my doc about prescribing that and so far he has resisted. What he said is that Seroquel would only make the daytime drowsiness worse. Does it have any effects beyond just a sleep aid (i.e., does it help with anxiety or depression?).

Malcolm

 

Re: Advice from Parnate users please.. » malcolm664

Posted by malcolm664 on June 13, 2007, at 20:09:58

In reply to Re: Advice from Parnate users please.. » sophia04, posted by malcolm664 on June 13, 2007, at 20:07:36

> > Thanks Malcom,
> > I did have an appointment finally w/ my doc and we decided to adjust the dose time - the daytime fatigue is so impactful to my work schedule and quality of life. I'm currently taking 30mg at 7:00pm and the other 30 mg at 10:00. I also (just last night) started taking 25 mg of Seroquel. Would you believe I still had insomnia and had to take ativan during the night on top of that?! Parnate's remedy-resistant insomnia is totally surreal. We shall see what happens tonight.
> > I'll continue to keep you all posted. Thanks!!
> >
>
> What's Seroquel like? I've asked my doc about prescribing that and so far he has resisted. What he said is that Seroquel would only make the daytime drowsiness worse. Does it have any effects beyond just a sleep aid (i.e., does it help with anxiety or depression?).
>
> Malcolm

Oops, I didn't notice that you had just started the Seroquel (which probably means that it's too soon for you to know whether it will help with anxiety or depression). But did it help you sleep?

 

Re: Advice from Parnate users please..

Posted by sophia04 on June 14, 2007, at 0:23:50

In reply to Re: Advice from Parnate users please.. » malcolm664, posted by malcolm664 on June 13, 2007, at 20:09:58

The first two nights I took Seroquel I got about 3 hours of uninterupted sleep. Docs wants me to go from 25mg to 50mg tonight. I was kind of groggy and did awake at 3;00 am w/ a banging headache, but feel a heck of a lot better than I did when I took the Parnate throughout the daytime. I also took a Provigil today because my doc gave me a few samples and I wanted to try it out - best day I've had in 10 weeks energy and mood-wise. Could it be the provigil? seroquel? parnate? So many variables at this point. I'll keep you posted though.

 

Re: Advice from Parnate (insomnia) users please..

Posted by sophia04 on June 14, 2007, at 19:09:48

In reply to Re: Advice from Parnate users please.., posted by sophia04 on June 14, 2007, at 0:23:50

LAst night I increased my Seroquel 50 mg and hardly got ANY sleep. This is crazy i know. I woke up after about an hour and struggled the rest of the night until I finally took lorazepam. My doc said this response is untypical, but I will go back down to 25mg for one more night before I move on to Ambien... i guess. I also feel pretty yucky today - naussea, hang-over, etc. My doc also tells me that she thinks the parnate induced insomnia will actually go away, or at least decrease. Has this been the case for ANYone out there?? Are there any long time users, who take the bulk of the parnate at night, use no sleep aids??

 

Re: Advice from Parnate (insomnia) users please.. » sophia04

Posted by psychobot5000 on June 15, 2007, at 8:03:48

In reply to Re: Advice from Parnate (insomnia) users please.., posted by sophia04 on June 14, 2007, at 19:09:48

> LAst night I increased my Seroquel 50 mg and hardly got ANY sleep. This is crazy i know. I woke up after about an hour and struggled the rest of the night until I finally took lorazepam. My doc said this response is untypical, but I will go back down to 25mg for one more night before I move on to Ambien... i guess. I also feel pretty yucky today - naussea, hang-over, etc. My doc also tells me that she thinks the parnate induced insomnia will actually go away, or at least decrease. Has this been the case for ANYone out there?? Are there any long time users, who take the bulk of the parnate at night, use no sleep aids??
________________

Okay, so Parnate-induced insomnia is not at all uncommon, though I believe you mentioned you were taking Provigil/modafinil, and that caused me insomnia when I took it, also. Parnate or other MAOi-induced insomnia does have the reputation of going away after a period of time weeks or months, usually. Maybe not completely, but significantly. Sleep is a problem on MAOis for some.

Do you find that the Parnate causes drowsy periods during the day? Sometimes you can time the dosing so that the drowsiness hits you at bedtime, or, failing that, you can try taking the entire dose as far away from bedtime as possible--though I don't think you're supposed to take it all at once.

Since MAOi-induced insomnia can sometimes be a serious problem, some users do have to take sleep aids all the time, it's true.

Hope you find something that works it out.

 

Re: Advice from Parnate (insomnia) bye bye Parnate

Posted by sophia04 on June 16, 2007, at 22:31:33

In reply to Re: Advice from Parnate (insomnia) users please.. » sophia04, posted by psychobot5000 on June 15, 2007, at 8:03:48

Yes, the sleep deprivation is maddening, but I'm also disillusioned by Parnate's lack of antidepressant effect on me. I still feel fundamentally depressed, zero motivation, obvious avoidance behavior + contending w/ these miserable side effects. It's been almost 11 weeks (5 on 60 mgs), I feel as though I've given this drug more than a fair shake. I'm going to say good-bye to Parnate and hope my doc has something more effective in mind. Open to suggestions.....

Thanks all,

Sophia


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