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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by cgd092 on January 4, 2007, at 18:35:05
About a week ago I started Lamotrigine (Lamictal). I'm only on 25mg/day so far. Now I have a lot of eyelid twitching. I found this on the net:
From: http://www.blepharospasm.org/2002jankovic.html
Tardive dystonia is probably the most common cause of secondary dystonia, including blepharospasm [Jankovic, 1995; Mauriello et al, 1998]. Tardive dystonia consists of a persistent dystonic movement involving chiefly the face, jaws, neck, trunk, and arms. Blepharospam may be the initial presentation of tardive dystonia [Sachdev, 1998]. In addition to dopamine-receptor blocking drugs (neuroleptics), there are other drugs that can cause blepharospasm, including lithium [Micheli et al, 1999], lamotrigine [Verma et al, 1999], and others [Mauriello et al, 1998].
What do you think? I also take 100mg/day of Seroquel and 40mg/day of Celexa.Too much drugs?
--Katy
Posted by yxibow on January 6, 2007, at 23:52:13
In reply to Twitching eyelids = blepharospasm ?, posted by cgd092 on January 4, 2007, at 18:35:05
> About a week ago I started Lamotrigine (Lamictal). I'm only on 25mg/day so far. Now I have a lot of eyelid twitching. I found this on the net:
>
> From: http://www.blepharospasm.org/2002jankovic.html
>
> Tardive dystonia is probably the most common cause of secondary dystonia, including blepharospasm [Jankovic, 1995; Mauriello et al, 1998]. Tardive dystonia consists of a persistent dystonic movement involving chiefly the face, jaws, neck, trunk, and arms. Blepharospam may be the initial presentation of tardive dystonia [Sachdev, 1998]. In addition to dopamine-receptor blocking drugs (neuroleptics), there are other drugs that can cause blepharospasm, including lithium [Micheli et al, 1999], lamotrigine [Verma et al, 1999], and others [Mauriello et al, 1998].
>
>
> What do you think? I also take 100mg/day of Seroquel and 40mg/day of Celexa.
>
> Too much drugs?
>
> --Katy
Well I can safely say you are on far less medication than I am on, although I am a larger male, I am surmising -- the Seroquel dose is pretty low and the Celexa is average.Nonetheless, one can suspect a new agent could cause some transient side effects and might be the cause of the blepharospasms. Certainly not Tardive. Tardive means late in treatment, as in many months to many years.
Also one has to remember that without any medication, blepharospasms are part of being human. People can have eyelid twitching that can last six months and can agreeably be fairly annoying. Botox might be necessary in the most severe cases, although that has the potential for lid drooping. Twitching can happen in any part of the body and is not necessarily a sign of medication. But you might want to discuss with your doctor about the Lamictal if you're especially concerned since it is the newest agent you've added.
Hope that helps
-- Jay
Posted by cgd092 on January 8, 2007, at 13:26:22
In reply to Re: Twitching eyelids = blepharospasm ? » cgd092, posted by yxibow on January 6, 2007, at 23:52:13
Well, the eyelid twitching has significantly subsided. I thought it was going to stay around, but you're right, it was a "transient side effect."
Thank you!
-Katy
This is the end of the thread.
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