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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by ace on August 14, 2006, at 0:51:45
Ok! Ace is sick of 10 yrs of smoking...no good for my vocals, health, breath around all the woman who want me (!!), and my room and clothes!
I'm adding on 300mg to nardil...I have seen VEY successful rersults for Wellbutrin on ASK A PAtient
Heard of quite a few combining MAOI with Wellbutrin!
Tell me your experiences!!!!!!!!!!
Ace
Nardil - 90
Xanax- 1.5
Seroquel- 25
Posted by Maxime on August 15, 2006, at 17:19:37
In reply to Wellbutrin with MAOI, posted by ace on August 14, 2006, at 0:51:45
It's probably contraindicated, but that doesn't mean much imho. Go for it! But what about the patch? Have you tried that route yet?
Maxime
> Ok! Ace is sick of 10 yrs of smoking...no good for my vocals, health, breath around all the woman who want me (!!), and my room and clothes!
>
> I'm adding on 300mg to nardil...I have seen VEY successful rersults for Wellbutrin on ASK A PAtient
>
> Heard of quite a few combining MAOI with Wellbutrin!
>
> Tell me your experiences!!!!!!!!!!
>
> Ace
> Nardil - 90
> Xanax- 1.5
> Seroquel- 25
Posted by willyee on August 15, 2006, at 21:30:41
In reply to Re: Wellbutrin with MAOI » ace, posted by Maxime on August 15, 2006, at 17:19:37
> It's probably contraindicated, but that doesn't mean much imho. Go for it! But what about the patch? Have you tried that route yet?
>
> Maxime
>
>
> > Ok! Ace is sick of 10 yrs of smoking...no good for my vocals, health, breath around all the woman who want me (!!), and my room and clothes!
> >
> > I'm adding on 300mg to nardil...I have seen VEY successful rersults for Wellbutrin on ASK A PAtient
> >
> > Heard of quite a few combining MAOI with Wellbutrin!
> >
> > Tell me your experiences!!!!!!!!!!
> >
> > Ace
> > Nardil - 90
> > Xanax- 1.5
> > Seroquel- 25
>
>
There is a really popular protocol data sheet,listing some extremly unconventional maoi use by MD`S.Most are done in a hospital setting,its a long data sheet,we had it posted here a few times,i will dig through and look for it.Straight to mind the combinations they worked with were Parnate with a added stimulant,either ritalin,or dex.
This was mentioned as being done very carefully in the process of which one to higher.
There was Parnate in combo with a few Tca`s,imiprimine being one totaly contradicted period.Amtrpyine was the one i believe used.
Then last there was parnate used in very,very high doses,one docter measured blood platets of the drug and commonly used close to 200 mg of parnate to reach the level of inhibition he wanted,he claimed maois are simply being given in far to low doses to build up to a therputic level.
Also of course duh Parnate was added at 60 mg,i remember this precise cause i tried it,with approx mmm i believe 300 mg wellbutrin.Anyway appearently the patient only stayed in remission on both,when one was removed her depression came back.
I tried this protocol exactly how it was mentioned,and after 7 days i felt an extreme depression,it wasnt till stopping wellbutrin for a good week that i felt ok again,so i had no benifit from the combo other than worsened depression.I also tried the ritalin parnate combo,and thought i had a remission,when in fact i was totaly maniac taking on projects left and right,not knowing the day or time or caring,that was very scary.
Actualy liquid deprenyl,in drops,done in very small drop increments,i.e 1 mg a day,i found more benificial and i felt safe for once,at one point i actualy felt better than ok on the two.Liquid deprenyl has to be used though,and even at the small droplets,the price of the liquid is so outrageous i simply could not afford it,or else id still try it.
I am pretty sure most of the protocols invovled Nardil as well,but id ge my hands on this data sheet its packed full of the unconventional maoi combos that were tried under a docters direct supervision.Unfortantly i found none to be helpful,but then again i could have been doing something wrong,again i found liquid deprenyl taken at small doses,which it is actualy spoken of for smoking cessation in some articles,the best combo.if i fine the article in the next hour ill post it
Posted by willyee on August 15, 2006, at 21:41:44
In reply to Re: Wellbutrin with MAOI » Maxime, posted by willyee on August 15, 2006, at 21:30:41
Here i remeber digging this up from this site in the archives,its not nardil,but its something to what is being asked........
**********Bupropion–Tranylcypromine for Refractory Depression
The combination of bupropion and tranylcypromine was used safely and successfully in a patient with chronic, treatment-resistant depression.1
A 27-year-old woman had a history of chronic major depression that had been refractory to trials of an SSRI and various TCAs, plus adjunctive methylphenidate. She had been started on 150 mg/day bupropion, and 2 months later, tranylcypromine was added and titrated to 50 mg/day. Her depressive symptoms slowly resolved.
Five months later, bupropion was tapered and stopped. Within 2 weeks her depressive symptoms recurred, but resolved after bupropion was restarted. A subsequent attempt to withdraw tranylcypromine was associated with a recurrence of mood symptoms.
For the last 2 years, she has remained on a regimen of 150 mg bupropion SR b.i.d. and 60 mg/day tranylcypromine, with no recurrence of depression. During that time she had 1 episode of symptomatic hypertension after eating cheese, which was managed at home with nifedipine. She has nifedipine available for a hypertensive crisis, and uses low-dose lorazepam as needed for mild transient episodes of stress-related dysphoria or insomnia.
According to the criteria of Thase and Rush, this patient’s poor response to multiple antidepressant trials classifies her depression at Stage IV resistance, making her a candidate for ECT.2 However, she preferred to stay employed and to receive outpatient treatment.
Discussion: The combination of bupropion and an MAOI is not generally recommended, because it can increase the risk for hypertensive crisis or may risk bupropion toxicity.3,4 However, cautious coadministration of bupropion and tranylcypromine may be a viable therapeutic option in patients who are unresponsive to trials of antidepressants.
1. Pierre J, Gitlin M: Bupropion-tranylcypromine combination for treatment-refractory depression (letter). Journal of Clinical Psychiatry 2000;61 (June):450–451. From UCLA Neuropsychiatric Institute, Los Angeles, Calif.
2. Thase M, Rush A: When at first you don’t succeed: sequential strategies for antidepressant nonresponders. Journal of Clinical Psychiatry 1997;58 (suppl 13):23–29.
3. Kaplan H, Sadock B, eds. Comprehensive Textbook of Psychiatry. 6th ed. Baltimore, Md: Lippincott, Williams & Wilkins; 1995.4. Product information. Bupropion (Wellbutrin). Glaxo Wellcome. May 1997.
Drug Trade Names: bupropion—Wellbutrin; lorazepam—Ativan; methylphenidate—Ritalin;
nifedipine—Adalat, Procardia; tranylcypromine—Parnate
Posted by kimcrazylady on August 17, 2006, at 11:43:59
In reply to Re: Wellbutrin with MAOI » willyee, posted by willyee on August 15, 2006, at 21:41:44
I am on Parnate and want to try an addition to get me out of this funk. I thought Seroquel was a no-no!?
I may ask about Wellbutrin the next time I go to my doc. He nixed the Provigil, even though I see many people who have combined the two :(
Please let us know if this works.
Kim
Posted by ace on August 19, 2006, at 0:01:54
In reply to Re: Wellbutrin with MAOI ?Maxime, posted by willyee on August 15, 2006, at 21:30:41
> > It's probably contraindicated, but that doesn't mean much imho. Go for it! But what about the patch? Have you tried that route yet?
> >
> > Maxime
> >
> >
> > > Ok! Ace is sick of 10 yrs of smoking...no good for my vocals, health, breath around all the woman who want me (!!), and my room and clothes!
> > >
> > > I'm adding on 300mg to nardil...I have seen VEY successful rersults for Wellbutrin on ASK A PAtient
> > >
> > > Heard of quite a few combining MAOI with Wellbutrin!
> > >
> > > Tell me your experiences!!!!!!!!!!
> > >
> > > Ace
> > > Nardil - 90
> > > Xanax- 1.5
> > > Seroquel- 25
> >
> >
>
>
> There is a really popular protocol data sheet,listing some extremly unconventional maoi use by MD`S.Most are done in a hospital setting,its a long data sheet,we had it posted here a few times,i will dig through and look for it.CAN YOU PLEASE PLEASE FIND THIS!!!!!!!!!!!
> Straight to mind the combinations they worked with were Parnate with a added stimulant,either ritalin,or dex.
>
> This was mentioned as being done very carefully in the process of which one to higher.
>
> There was Parnate in combo with a few Tca`s,imiprimine being one totaly contradicted period.Amtrpyine was the one i believe used.
>
>
> Then last there was parnate used in very,very high doses,one docter measured blood platets of the drug and commonly used close to 200 mg of parnate to reach the level of inhibition he wanted,he claimed maois are simply being given in far to low doses to build up to a therputic level.
>
>
> Also of course duh Parnate was added at 60 mg,i remember this precise cause i tried it,with approx mmm i believe 300 mg wellbutrin.Anyway appearently the patient only stayed in remission on both,when one was removed her depression came back.
>
>
> I tried this protocol exactly how it was mentioned,and after 7 days i felt an extreme depression,it wasnt till stopping wellbutrin for a good week that i felt ok again,so i had no benifit from the combo other than worsened depression.
>
> I also tried the ritalin parnate combo,and thought i had a remission,when in fact i was totaly maniac taking on projects left and right,not knowing the day or time or caring,that was very scary.
>
>
> Actualy liquid deprenyl,in drops,done in very small drop increments,i.e 1 mg a day,i found more benificial and i felt safe for once,at one point i actualy felt better than ok on the two.
>
> Liquid deprenyl has to be used though,and even at the small droplets,the price of the liquid is so outrageous i simply could not afford it,or else id still try it.
>
>
> I am pretty sure most of the protocols invovled Nardil as well,but id ge my hands on this data sheet its packed full of the unconventional maoi combos that were tried under a docters direct supervision.
>
> Unfortantly i found none to be helpful,but then again i could have been doing something wrong,again i found liquid deprenyl taken at small doses,which it is actualy spoken of for smoking cessation in some articles,the best combo.if i fine the article in the next hour ill post it
>
Posted by willyee on August 23, 2006, at 18:34:32
In reply to Re: Wellbutrin with MAOI » willyee, posted by ace on August 19, 2006, at 0:01:54
I did,i cant make out anything with all the posts,but i posted it that night a few minutes after the post in question,if its not there,or u need it,start a new post so i can see on the bottom and ill paste it again,i cant seem to make out if its still there or not.
FYi its the maoi/wellbutrin combo info.
Posted by jedi on August 27, 2006, at 1:40:55
In reply to Wellbutrin with MAOI, posted by ace on August 14, 2006, at 0:51:45
> Ok! Ace is sick of 10 yrs of smoking...no good for my vocals, health, breath around all the woman who want me (!!), and my room and clothes!
>
> I'm adding on 300mg to nardil...I have seen VEY successful rersults for Wellbutrin on ASK A PAtient
>
> Heard of quite a few combining MAOI with Wellbutrin!
>
> Tell me your experiences!!!!!!!!!!
>
> Ace
> Nardil - 90
> Xanax- 1.5
> Seroquel- 25Hi Ace,
I have mixed the two medications (Nardil-90mg and bupropion-300mg). The mixture helped with some of the weight gain caused by Nardil. Of course they are contraindicated, probably because no studies have been done. Bupropion always makes me somewhat aggressive for several weeks when I start it.
Good Luck,
Jedi
Posted by SLS on August 29, 2006, at 9:39:41
In reply to Re: Wellbutrin with MAOI, posted by jedi on August 27, 2006, at 1:40:55
I once mixed Parnate and Wellbutrin. The only problem I had with the combination is that it didn't work. Otherwise, it seemed to be safe and without major side effects.
- Scott
Posted by willyee on September 1, 2006, at 12:40:00
In reply to Re: Wellbutrin with MAOI, posted by SLS on August 29, 2006, at 9:39:41
> I once mixed Parnate and Wellbutrin. The only problem I had with the combination is that it didn't work. Otherwise, it seemed to be safe and without major side effects.
>
>
> - Scott
Agreed and for me it also lowered parnates already disappearing effect,the mix created a odd mixture effect i did not find helpful at all,wish i had the opposite to say its just the truth in my case.
This is the end of the thread.
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