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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 17 of 17. This is the beginning of the thread.
Posted by MARTY on May 20, 2006, at 1:26:50
May 18 - Day 1First dose of 150mg may the 18:
45 mins latter feeled like dazed, druged.
Wasn't a very bad thing if it was of
the fact I was trying to code a software
and at the same time trying to understand
the boring stuff my co-worker tells me
about his latest World Of Warcraft game :SAfter 30 mins later I start to feel stimulated
and energized. I wonder how it could be since
it was only my FIRST DOSE. But that's it and I'm
can do nothing but tell you ;)Side effects: initial sedation, little dizziness, heartburn.
Marty
Posted by MARTY on May 20, 2006, at 1:56:11
In reply to Journal - Moclobemide (MANERIX), posted by MARTY on May 20, 2006, at 1:26:50
May 18 - Manerix day 2My first dose was exactly like day 1.
The stimulating effect at physical and intellectual level is much welcome and feel much more natural for me than any other stimulating AD I tried so far (ex: Parnate, Wellbutrin).
But keep in mind that it is only my feeling of
it just 2 day after starting it.. so it doesn't
worth much ;)So.. After my seconde dose.. after a couple hours
later..I ate a pizza (yes, with pepperoni etc) in a
reputed pizzeria. Fresh topings etc.. after I
went to go see a movie (DaVinci Code) and had a
sudden rise of Blood Pression that I felt in my
head. I don't have any proof that it was an BP
increase cause I didnt have my 'BP reader' but
something was going on.. I had some rush like
I was to start to panic or have a seizure.. this
was like a sudden rush going right to the head
giving me the feeling that whatever it was could
have make me lost control over myself..PS: never had a panic attack or seizure.
PS2: Had those feeling while starting Nardil.. sometime even stronger.. I learned to ignore it. But this time couldn't do.Marty
Posted by Declan on May 20, 2006, at 2:19:08
In reply to MAY 19 - MANERIX DAY 2, posted by MARTY on May 20, 2006, at 1:56:11
Some people don't notice it, but I found it pretty potent. I was quicker, but it was a bit of a strain too. And that was only 75mg.
You're on 300mg/d?
Posted by Phillipa on May 20, 2006, at 11:49:11
In reply to Re: MAY 19 - MANERIX DAY 2, posted by Declan on May 20, 2006, at 2:19:08
Sorry for my ignorance is this another MAOI? Love Phillipa
Posted by MARTY on May 20, 2006, at 14:13:22
In reply to Re: MAY 19 - MANERIX DAY 2, posted by Declan on May 20, 2006, at 2:19:08
> You're on 300mg/d?
Yes on 300 (150 AFTER breakfast, 150 AFTER supper).
I agree, the effect is much more pronounced than what I've read so far. It's not the same stimulation that provide Parnate, but for me it feels much more natural.
Marty
Posted by Declan on May 20, 2006, at 14:23:50
In reply to Re: MAY 19 - MANERIX DAY 2 » Declan, posted by MARTY on May 20, 2006, at 14:13:22
No problems with sleep, then? Moclobemide never made me tired like Parnate can. Maybe if I'd taken more moclobemide there would have been tiredness.
Declan
Posted by MARTY on May 20, 2006, at 15:11:15
In reply to Re: MAY 19 - MANERIX DAY 2, posted by Declan on May 20, 2006, at 14:23:50
> No problems with sleep, then?
Not at this time. Maybe the first dose did stimulate me enough so I did go to bed later (much later, 5Am :S )
> Moclobemide never made me tired like Parnate can.
That's music to my hear :) seriously that's good news: Parnate fatigue are hard to deal with.
Any side effects ? do you feel sedate the first hour when you take a dose ? do you feel sometimes a 'build up', a pression in your head ?Marty
Posted by Declan on May 20, 2006, at 17:23:18
In reply to Re: MAY 19 - MANERIX DAY 2 » Declan, posted by MARTY on May 20, 2006, at 15:11:15
After a small dose of moclobemide I would feel stimulated. I can't recall feeling tired. Like butterflies in my stomach and an edgy feeling. I was quicker to understand things and reply, but I didn't feel more comfortable. I would take moclobemide again, just being careful to avoid the agitation and general feelings of freakiness. It did take away some kind of weight.
I can't recall a feeling of compression in my head. I was much chattier, and also feeling mildly desperate.
Declan
Posted by MARTY on May 20, 2006, at 22:41:15
In reply to Re: MAY 19 - MANERIX DAY 2, posted by Declan on May 20, 2006, at 17:23:18
> After a small dose of moclobemide I would feel stimulated. I can't recall feeling tired.
Maybe it's dose related.
> Like butterflies in my stomach and an edgy feeling. I was quicker to understand things and reply, but I didn't feel more comfortable.
I can relate to that.. comfortable? about depression or OCD or Social Phobia or .... ...
> I would take moclobemide again, just being careful to avoid the agitation and general feelings of freakiness.
Feelings of freakiness .. ugh This isn't very
encouraging lol you mean you feeled druged or
maybe different ?>It did take away some kind of weight.
Tell me you are talking about real weights.. the
one we count in pounds :P> I can't recall a feeling of compression in my head. I was much chattier, and also feeling mildly desperate.
hmmm .. it scares me a little cause I heard many people saying it was agravating their depression. That's weird.
btw what's your cocktail right now and how do you feel ?
Marty
Posted by Declan on May 20, 2006, at 23:03:33
In reply to Re: MAY 19 - MANERIX DAY 2 » Declan, posted by MARTY on May 20, 2006, at 22:41:15
I'm taking tianeptine now. The good thing about it is that I sleep well on it. I feel a bit fuzzy though. No bad sexual effects, so they say and so it seems.
I didn't feel very calm on Mannerix. Not drugged though. And I felt better than normal. The idea of moclobemide and a benzo makes some kind of sense.
I don't suppose any of these drugs is going to be quite right, unless you're very lucky.
Posted by Maximus on May 20, 2006, at 23:03:53
In reply to Re: MAY 19 - MANERIX DAY 2 » Declan, posted by MARTY on May 20, 2006, at 22:41:15
Hi Marty,
Good to hear you're feeling well on Moclo. That's a solid rocket booster, you know. Really. But be warned, above 600 mgs you may experience anxiety and agitation. Increase the dose slowly. Good luck!
Posted by MARTY on May 20, 2006, at 23:54:22
In reply to Re: MAY 19 - MANERIX DAY 2 » MARTY, posted by Declan on May 20, 2006, at 23:03:33
> I'm taking tianeptine now. The good thing about it is that I sleep well on it. I feel a bit fuzzy though. No bad sexual effects, so they say and so it seems.
Do you have a prescription for it ? where do you live ?
> I didn't feel very calm on Mannerix. Not drugged though. And I felt better than normal. The idea of moclobemide and a benzo makes some kind of sense.Yes, but I think it all depends on your diagnostic.
> I don't suppose any of these drugs is going to be quite right, unless you're very lucky.You're damn right! tried enough to know that.
Just to be sure.. which kind of "weight" were you talking in your last post ? real weight (pounds etc) ?Marty
Posted by MARTY on May 20, 2006, at 23:59:21
In reply to Re: MAY 19 - MANERIX DAY 2 » MARTY, posted by Maximus on May 20, 2006, at 23:03:53
> Good to hear you're feeling well on Moclo.
Well, it's a start :P I'm only on it since 3 days. Should I expect to already feel the full potential, the full effect of Moclo after only 3 days ?
> But be warned, above 600 mgs you may experience anxiety and agitation. Increase the dose slowly.
Good to know! I will.
>Good luck!
Thanks
Posted by Maximus on May 21, 2006, at 0:59:28
In reply to Re: MAY 19 - MANERIX DAY 2 » Maximus, posted by MARTY on May 20, 2006, at 23:59:21
> > Good to hear you're feeling well on Moclo.
>
> Well, it's a start :P I'm only on it since 3 days. Should I expect to already feel the full potential, the full effect of Moclo after only 3 days ?The real antidepressant effect of Moclo, i mean the anti-melancholic one, should take place within 10 days. It's really fast.
If you're bipolar, a mood stabilizer is essential as you might switch into a "dark dysphoria". Not nice.
Do you appreciate yet the pro-sexual effect, if i may ask? Do you still take Risperdal? I do not remember. It was the most offensive in that department. Prolactin related... You may find Seroquel neutral for that. But i do reckon the amazing effect and peace of Risperdal.
Posted by MARTY on May 21, 2006, at 1:29:05
In reply to Re: MAY 19 - MANERIX DAY 2 » MARTY, posted by Maximus on May 21, 2006, at 0:59:28
> The real antidepressant effect of Moclo, i mean the anti-melancholic one, should take place within 10 days. It's really fast.10 days is good enough for me, I'm not that bad.
> If you're bipolar, a mood stabilizer is essential as you might switch into a "dark dysphoria". Not nice.Never been proofed, but Pdocs says I could be
Bipolar II .. I only takes Lamictal 300mg and
Risperdal .25 so I dont like the term "dark
dysphoria" which sounds like one of the worst
kind of depression state one can get or something. I'll do search on that.. it may be
a good thing to raise my lamictal or Riperdal.
> Do you appreciate yet the pro-sexual effect, if i may ask?Well, not sure if there is a link to be made but I feel like I never did it: last time I did it with my girlfriend it lasted like 2 min MAX.. I think it's because I've been doing some genital anestesia on my 2 last AD and now I need to get used to feeling it again LOL ..
> Do you still take Risperdal? I do not remember. It was the most offensive in that department. Prolactin related...Yes I take a small dose of Risperdal, but I'm very sensitive to it. Talking prolactin, I'll see a Pdoc the 1st June that may try testosterone on me. My level is bordeline, that's why.
> You may find Seroquel neutral for that. But i do reckon the amazing effect and peace of Risperdal.I agree with you about Risperdal. I did tried
Seroquel for a time but I was to sensitive to the anticholinergic effect..BTW, did you tried it for yourself ? Can you describe me your experience if you dont care ...
Marty
Posted by Maximus on May 21, 2006, at 2:19:22
In reply to Re: MAY 19 - MANERIX DAY 2 » Maximus, posted by MARTY on May 21, 2006, at 1:29:05
> BTW, did you tried it for yourself ? Can you describe me your experience if you dont care ...
>
> Marty
>Hi,
Yes i tried it myself. I have had a great and bad experience with Moclo. To make a long story short, i have taken Manerix for 6 weeks approx. It has been great for the first 4 weeks. Energy, depression, anxiety, sexuality, cognition, name it, i have had a TOTAL remission. Probably too well. At that time, (9 or 10 years ago?), i hadn't been yet diagnosed bipolar II. Then i felt into a very dark dysphoria (deep despair, anxiety, rage, insomnia), etc. Misery...
The switch rate is like a TCA, not worse.
But i guess that if you're "shielded" by a good mood stabilizer, you're in business. BTW, as you probably know, Lamictal is very poor at preventing a hypomanic/manic episode. Risperidone is your safety net here.
So don't worry, keep on taking Manerix. You should be satisfied of this med.
Posted by MARTY on May 21, 2006, at 16:58:08
In reply to Re: MAY 19 - MANERIX DAY 2 » MARTY, posted by Maximus on May 21, 2006, at 2:19:22
Yeah, Lamictal is better for his antidepressive effect. My dose of Risperdal may not be sufficient to keep me stabilized, so that a thing I need to discust with my Pdoc.Thanks for all the infos and for having shared your experience with me.
Marty
> > BTW, did you tried it for yourself ? Can you describe me your experience if you dont care ...
> >
> > Marty
> >
>
> Hi,
>
> Yes i tried it myself. I have had a great and bad experience with Moclo. To make a long story short, i have taken Manerix for 6 weeks approx. It has been great for the first 4 weeks. Energy, depression, anxiety, sexuality, cognition, name it, i have had a TOTAL remission. Probably too well. At that time, (9 or 10 years ago?), i hadn't been yet diagnosed bipolar II. Then i felt into a very dark dysphoria (deep despair, anxiety, rage, insomnia), etc. Misery...
>
> The switch rate is like a TCA, not worse.
>
> But i guess that if you're "shielded" by a good mood stabilizer, you're in business. BTW, as you probably know, Lamictal is very poor at preventing a hypomanic/manic episode. Risperidone is your safety net here.
>
> So don't worry, keep on taking Manerix. You should be satisfied of this med.
This is the end of the thread.
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