![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 21 of 21. This is the beginning of the thread.
Posted by Emme on February 14, 2006, at 22:31:06
Hi All,
I know this is probably very unlikely, but has anyone experienced worsened depression from augmentin or a similar antibiotic?
Thanks,
emme
Posted by SLS on February 14, 2006, at 23:08:22
In reply to depression from antibiotic?, posted by Emme on February 14, 2006, at 22:31:06
> Hi All,
>
> I know this is probably very unlikely, but has anyone experienced worsened depression from augmentin or a similar antibiotic?Yes and no. It probably does feel like your depression is getting worse. I believe this is part of feelings of general malaise that can occur as a side effect. It probably is not worsening the affective disorder itself.
One thing seen with the depression produced by Lyme Disease and its treatment with doxycycline is the occurrence of waves of worsening before remission is achieved.
- Scott
Posted by Emme on February 15, 2006, at 17:58:07
In reply to Re: depression from antibiotic?, posted by SLS on February 14, 2006, at 23:08:22
> > I know this is probably very unlikely, but has anyone experienced worsened depression from augmentin or a similar antibiotic?
>
> Yes and no. It probably does feel like your depression is getting worse.Oh yeah... heavy despair and hopelessness and tearfulness of a sort that I haven't had in a long while.
> I believe this is part of feelings of general malaise that can occur as a side effect. It probably is not worsening the affective disorder itself.
You mean feeling more depressed just because of feeling ill from the infection and the antibiotic? Could be. Being out of commission for several days isn't doing much for my mental state. I suppose I just have to ride it out and figure it'll resolve soon.
> One thing seen with the depression produced by Lyme Disease and its treatment with doxycycline is the occurrence of waves of worsening before remission is achieved.We're seeing this with a friend who's being treated for Lyme. Poor thing.
emme
Posted by fires on February 15, 2006, at 20:53:47
In reply to depression from antibiotic?, posted by Emme on February 14, 2006, at 22:31:06
> Hi All,
>
> I know this is probably very unlikely, but has anyone experienced worsened depression from augmentin or a similar antibiotic?
>
> Thanks,
> emmeAccording to my previous doc who taught psychopharmacology at a major university: definitely possible with any antibiotic. I never heard him say how likely it is though.
Cycloserine is known for causing psych. problems. Some refer to it as psychoserine.
http://www.merck.com/mmhe/sec07/ch101/ch101b.html
I may be able to dig up more info.
Posted by fires on February 15, 2006, at 21:12:04
In reply to Re: depression from antibiotic? » Emme, posted by fires on February 15, 2006, at 20:53:47
> > Hi All,
> >
> > I know this is probably very unlikely, but has anyone experienced worsened depression from augmentin or a similar antibiotic?
> >
> > Thanks,
> > emme
>
> According to my previous doc who taught psychopharmacology at a major university: definitely possible with any antibiotic. I never heard him say how likely it is though.
>
> Cycloserine is known for causing psych. problems. Some refer to it as psychoserine.
>
> http://www.merck.com/mmhe/sec07/ch101/ch101b.html
>
> I may be able to dig up more info.
>
>
More info.:"Almost all antibiotics appear to have psychotropic functions. These are mainly reported in the context of adverse reactions but can be used therapeutically. The neuropsychopharmacologic effect of most antibiotics is as GABA antagonists."
From: "Tuning the Brain" by Jay Goldstein.
The book has more info.
Posted by Phillipa on February 15, 2006, at 21:15:50
In reply to Re: depression from antibiotic?, posted by SLS on February 14, 2006, at 23:08:22
Scott I have chronic lyme disease. During one of my treatment phases I had a lot of twitching in my lower legs. Well the infection control specialist put me on doxycylline the drug of choice for lymes. Especially if the infection is new. Well after one dose the twitching stopped. But this doc was an idiot he didn't believe in treating chronic lymes. Fast forward. Western Blot positive again the Health Dept in Charlotte calls wants to know what treatment I'm receiving refer him the rheumatologist who looked over my recent results of tests and past medical records. A few years ago I was given Rocephin Iv and it was discontinued from what the docs thought was an allergic reaction. The reaction was that twitching. The doc I recently saw said "how many tx's did you receive how many day were you on it?" I said five he said "Wait" that twitiching was s sign that the spirochettes were being killed. So now you can consider you self free from the lymes's disease. Moral of story is that it seem s not to effect my depression it's just there. Now there's always the change that the lymes may have caused cognitive impairment but there is not a test to determine this. Just take Ad's. That's all you can do. Oh and chronic fatigue is an end result of lymes disesse. Fondly, Phillipa
Posted by SLS on February 16, 2006, at 7:48:45
In reply to Re: depression from antibiotic? » SLS, posted by Phillipa on February 15, 2006, at 21:15:50
It seems that you've become quite an expert in Lyme disease. It is unfortunate that such expertise is often the result of personal suffering.
I'm sorry you had to go through the medical guessing game with Lyme. Perhaps you can be on the lookout for others whom might be suffering from it, but for whom no one else recognizes the symptoms.
I hope you feel better soon.
- Scott
Posted by Emme on February 16, 2006, at 11:55:00
In reply to Re: depression from antibiotic? » fires, posted by fires on February 15, 2006, at 21:12:04
Posted by Emme on February 16, 2006, at 11:59:10
In reply to Re: depression from antibiotic? » SLS, posted by Phillipa on February 15, 2006, at 21:15:50
Are you currently receiving antibiotic treatment? Based on what I see with a friend going through this, chronic Lyme disease looks like a heckuva long, hard ordeal.
emme
Posted by Phillipa on February 16, 2006, at 12:24:02
In reply to Re: depression from antibiotic? » Phillipa, posted by Emme on February 16, 2006, at 11:59:10
No the doctor said I didn't require further antibiotic treatment. but there was a poster who said to find an LLMD. Does anyone know how to find one I've tried even joined the lymes website and still see no where to find a docor although it says you can I was corresdonding a year ago with a person who saw one I'll E-mail her now and see if I can find out the name of State and doc she saw. I stopped writing with her as she was sending so many articles I couldn't keep up with them. Thanks Scott Love Jan
Posted by Emme on February 16, 2006, at 12:39:11
In reply to Re: depression from antibiotic? » Emme, posted by Phillipa on February 16, 2006, at 12:24:02
Have you contacted this organization:
Lyme Disease Association
1-888-366-6611I'm told that if you call them and leave a voice message, that they will get back to you and try to give you a referral for a doctor. It may take several days for them to get back to you, so be patient.
There is also an e-mail address:
referrals@LymeDiseaseAssociation.orgI have not personally dealt with them (no sign that I have the disease), but my friend with chronic Lyme disease gave me this information for another friend.
emme
> No the doctor said I didn't require further antibiotic treatment. but there was a poster who said to find an LLMD. Does anyone know how to find one I've tried even joined the lymes website and still see no where to find a docor although it says you can I was corresdonding a year ago with a person who saw one I'll E-mail her now and see if I can find out the name of State and doc she saw. I stopped writing with her as she was sending so many articles I couldn't keep up with them. Thanks Scott Love Jan
Posted by kerria on February 16, 2006, at 16:57:13
In reply to depression from antibiotic?, posted by Emme on February 14, 2006, at 22:31:06
i experienced very bad sedation and dizziness from taking the antibiotic erythromycin with diazapam. It happened about twenty minutes after taking the diazapam in the afternoon and lasted the rest of the day.
Are you taking any meds? Maybe the meds that you're taking for depression or something else interact with the antibiotic?
TC,
kerria
Posted by forgetful mary on February 16, 2006, at 17:44:10
In reply to Re: depression from antibiotic?, posted by kerria on February 16, 2006, at 16:57:13
Didn't Jane Pauley say her depression was caused by antibiotics???
Posted by Phillipa on February 16, 2006, at 19:11:30
In reply to Re: depression from antibiotic?, posted by forgetful mary on February 16, 2006, at 17:44:10
E-mailed the person and the mail was sent back. Said mail box full does that mean it's still valid? Fondly, Phillipa
Posted by Phillipa on February 16, 2006, at 19:21:22
In reply to Re: depression from antibiotic? » Phillipa, posted by Emme on February 16, 2006, at 12:39:11
Emme I sent an E-mail to the link asking for a referral for an LLMD. Thanks so much for the link. Would like to put this issue to bed. Fondly, Phillipa
Posted by Emme on February 17, 2006, at 12:02:55
In reply to Re: depression from antibiotic? » Emme, posted by fires on February 15, 2006, at 20:53:47
I have seen my pdoc. When I told her that I'm on an antibiotic she said that they can cause depression and she has seen this. We are waiting until I'm finished with my course of augmentin to see if my depressed mood eases up. She also said I should stay away from dextromethorphan - even though I'm not on an MAOI or SSRI.
Interesting.
So now I am counting the days till I'm done with the stuff.
emme
Posted by fires on February 17, 2006, at 12:53:56
In reply to My doc says..., posted by Emme on February 17, 2006, at 12:02:55
> I have seen my pdoc. When I told her that I'm on an antibiotic she said that they can cause depression and she has seen this. We are waiting until I'm finished with my course of augmentin to see if my depressed mood eases up. She also said I should stay away from dextromethorphan - even though I'm not on an MAOI or SSRI.
>
> Interesting.
>
> So now I am counting the days till I'm done with the stuff.
>
> emme
>My neuro told me the exact same thing about dextro., and I don't take an MAOI or SSRI either.
Posted by Gabbix2 on February 18, 2006, at 13:27:58
In reply to My doc says..., posted by Emme on February 17, 2006, at 12:02:55
I'm a little late, but I wanted to reassure you that yes, they can knock you on your a** as far as depression and anxiety.
I didn't know that myself, but when I was on Cipro recently after a round of different antibiotics, all my symptoms of depression/anxiety came back and it was terrifying. It was so bad that even though I could see myself getting better daily, I had to psych myself up to actually take the medication.
There's also the Herxheimer reaction that can happen when the toxins from dying bacteria overload your system and make you feel awful.
But in my experience that's quite different than the acute mental changes that occured with Cipro.I looked it up, and there is actually an article in Pub Med on Antibiotic induced depression.
It's occurs mostly (or has been noted mostly) with fluoriquinone antibiotics, but it's happened to me less severely with tetracylines as well.
Posted by Emme on February 18, 2006, at 15:10:37
In reply to Re: My doc says... » Emme, posted by Gabbix2 on February 18, 2006, at 13:27:58
> I'm a little late, but I wanted to reassure you that yes, they can knock you on your a** as far as depression and anxiety.
Can they knock you on your <donkey synonym> as far as weakness and fatigue also? It seems that my infection is cleared up enough that I should perk up, but I feel like a wet noodle.
> I didn't know that myself, but when I was on Cipro recently after a round of different antibiotics, all my symptoms of depression/anxiety came back and it was terrifying. It was so bad that even though I could see myself getting better daily, I had to psych myself up to actually take the medication.
That does sound scary. I suspect in my case the dextromethorphan in the cough syrup wasn't helping things any either.
> It's occurs mostly (or has been noted mostly) with fluoriquinone antibiotics, but it's happened to me less severely with tetracylines as well.
Thanks - I appreciate your input.
emme
Posted by Emme on February 18, 2006, at 15:12:30
In reply to Re: My doc says... » Emme, posted by fires on February 17, 2006, at 12:53:56
> My neuro told me the exact same thing about dextro., and I don't take an MAOI or SSRI either.I could swear I was more weepy on the stuff, but the coughing was bad enough that I caved and took it.
emme
Posted by fires on February 18, 2006, at 17:20:05
In reply to Re: My doc says... » fires, posted by Emme on February 18, 2006, at 15:12:30
>
> > My neuro told me the exact same thing about dextro., and I don't take an MAOI or SSRI either.
>
> I could swear I was more weepy on the stuff, but the coughing was bad enough that I caved and took it.
>
> emmeEven though I've been off of Parnate for almost 3 years I'm still on an MAOI diet and med restrictions, except for epi and some others.
(I've never tolerated yeasty, aged food, cheese etc.. well)
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.