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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by Paulbwell on November 1, 2005, at 4:26:02
Many say Ritalin (Methylphenidate) is more effective crushed and snorted naselly?
True?
Posted by Chairman_MAO on November 1, 2005, at 8:46:14
In reply to Ritalin (Methylphenidate)-more effective intranase, posted by Paulbwell on November 1, 2005, at 4:26:02
If you manage to get the drug to the area of the nasal passages where there are blood vessels that lead directly to the CSF, bypassing the BBB, then yes.
Otherwise, no, the bioavailability is probably the same or LESS than taking it orally, especially if one is snorting pills and not pure methylphenidate.
BTW, methylphenidate + alcohol in vivo produces ethylphenidate, a more euphorogenic compound with unknown toxicity. This is quite similar to how cocaine + alcohol = cocaethylene in vivo.
Most people do not know this. If you are an alcoholic, stay away from ritalin and take amphetamine instead.
Posted by willyee on November 1, 2005, at 14:24:24
In reply to Ritalin (Methylphenidate)-more effective intranase, posted by Paulbwell on November 1, 2005, at 4:26:02
> Many say Ritalin (Methylphenidate) is more effective crushed and snorted naselly?
>
> True?
Im a user of ritalin now,combined with parnate for energy.All i can say is YESS YESS YESS ABSOLUTLY SO.......Not on a proud basis,but in seek of relieaf i began using ritalin,same dose that way.Much more potent,faster,all around better....
That wasnt a problem,except when i added XYREM in the mix.....for approx 2 weeks i indulged in a ritalin/xyrem mix,using ritalin as described,and i was the most social butterfly u can be,happy as u can be.Id get through the day,would not care how bad it was cause i knew the night would be GREAT.THE problem,i know it was an illusion,feeling so great,warm,ease,social,i still barly left the house,and i knew when it stopped,id be in a lot and lot of trouble.
When i decedied to end this magic show of happiness,severe intense depression followed.Im not out of xyrem with no plans to get it,however im waiting on ritalin and im wondering if i should even get it.
It seems like were not allowed to find means to feeling happy,unless its destructive one,i am pretty frustrated,confused to take the ritalin cause i know i will only due it the form we speak of now.But im doing so bad now is not doing it any smarter?
Posted by Chairman_MAO on November 1, 2005, at 19:58:57
In reply to Re: Ritalin (Methylphenidate)-more effective intranase, posted by willyee on November 1, 2005, at 14:24:24
I am going to suggest phenelzine 1mg/kg to you until my fingers fall off and/or turn to dust upon my keyboard!
Posted by willyee on November 1, 2005, at 20:14:43
In reply to Re: Ritalin (Methylphenidate)-more effective intra » willyee, posted by Chairman_MAO on November 1, 2005, at 19:58:57
Lol well soon i will have no other options,parnate is becomming totaly ineffeffective.Working out has always been my thing,least i had that to take peoples mind off of the fact i am not doing sh*t with mysel,they kinda aww away at me and ask about that.If i cant lift like im having trouble now,i will selfishy force myself to nardil.
Parnate is making me sooo weak.
Posted by Paulbwell on November 3, 2005, at 0:04:14
In reply to Re: Ritalin (Methylphenidate)-more effective intra, posted by willyee on November 1, 2005, at 20:14:43
> Lol well soon i will have no other options,parnate is becomming totaly ineffeffective.Working out has always been my thing,least i had that to take peoples mind off of the fact i am not doing sh*t with mysel,they kinda aww away at me and ask about that.If i cant lift like im having trouble now,i will selfishy force myself to nardil.
>
> Parnate is making me sooo weak.There is no doubt that crushing and snorting is stronger and often, longer acting than oral admin. I am not proud of the fact, but having experimented with different MOA, nasal admin has had a dramatic effect (i have read it's as much as 10x as effective-entering the brain) I have SEVERAL times gone from drunk, to sober-very quickly- after snorting 20-30mgs methylphenidate.
This is NOT healthy or threaputic-i know full well, BUT, has often helped in certain emotional states.-Apparently (the VERY DANGEROUS practice of IV injection of Rit) is indistinguisable from IV Cocaine Hcl)-good thing i'm needle phobic.I guess thats why the medicine srrips state FOR ORAL ADMIN-i guess the manufacturactures know?.
Cheers
Posted by willyee on November 3, 2005, at 1:52:51
In reply to NO DOUBT-intranasal Ritalin is quicker, srtonger!!, posted by Paulbwell on November 3, 2005, at 0:04:14
In all honesty though i dont crave it,it just works,hell i can be laid out depressed,weak,do that,and im up simple as that.Alone i dident crave it i dident seem to become tolerant.
Its only when i combined it with xyrem that it was a problem,i indulged it,but thats done with.IM actualy wondering how a ritalin/l theanine combo would work..
Posted by Paulbwell on November 3, 2005, at 3:52:18
In reply to Re: NO DOUBT-intranasal Ritalin is quicker, srtonger!!, posted by willyee on November 3, 2005, at 1:52:51
> In all honesty though i dont crave it,it just works,hell i can be laid out depressed,weak,do that,and im up simple as that.Alone i dident crave it i dident seem to become tolerant.
>
> Its only when i combined it with xyrem that it was a problem,i indulged it,but thats done with.IM actualy wondering how a ritalin/l theanine combo would work..So you have IM Ritalin? mmmmmmmmmm-not good.
Sublingually methylphenidate works well, but Snorting say 10-30mgs has a PROFOUND efect efect, as you describe, it's a good thing i have a good LEGAL supply.
When all is said and done, feeling better is ALL that counts.
Posted by Declan on November 3, 2005, at 6:15:02
In reply to NO DOUBT-intranasal Ritalin is quicker, srtonger!!, posted by Paulbwell on November 3, 2005, at 0:04:14
Hey Paul, No. IV cocaine and IV Ritalin are as different as you'd expect. For some reason with cocaine the more indirect routes are much more euphoric for me. Maybe with Ritalin too, it's a long time since I banged it up. Certain emotional states eh? There is something to be said for dealing with them decisively.
Declan
Posted by Paulbwell on November 3, 2005, at 6:46:54
In reply to Re: NO DOUBT-intranasal Ritalin is quicker, srtonger!!, posted by Declan on November 3, 2005, at 6:15:02
> Hey Paul, No. IV cocaine and IV Ritalin are as different as you'd expect. For some reason with cocaine the more indirect routes are much more euphoric for me. Maybe with Ritalin too, it's a long time since I banged it up. Certain emotional states eh? There is something to be said for dealing with them decisively.
> DeclanFrom what i'v read, and seen methylphenidate Hcl and cocaine hcl, IVd read, are VERY similar in effect, and subjects given each often CANNOT tell the difference.
IVing tabs of Ritalin is very dangerous, due to the binders ETC.
mmmmmm
Posted by Declan on November 3, 2005, at 14:14:17
In reply to Re: NO DOUBT-intranasal Ritalin is quicker, srtonger!!, posted by Paulbwell on November 3, 2005, at 6:46:54
Can't be good for your kidneys, eyes or lungs.
Declan
Posted by paulbwell on November 3, 2005, at 16:16:37
In reply to Re: NO DOUBT-intranasal Ritalin is quicker, srtonger!! » Paulbwell, posted by Declan on November 3, 2005, at 14:14:17
> Can't be good for your kidneys, eyes or lungs.
> DeclanYes agreed IV Methylphenidate is VERY dangerous.
Many health problems-your comments made me think you had done IV Cocaine+Methylphenidate?
Cheers
Posted by willyee on November 3, 2005, at 18:43:04
In reply to Re: NO DOUBT-intranasal Ritalin is quicker, srtonger!!, posted by paulbwell on November 3, 2005, at 16:16:37
> > Can't be good for your kidneys, eyes or lungs.
> > Declan
>
> Yes agreed IV Methylphenidate is VERY dangerous.
>
> Many health problems-your comments made me think you had done IV Cocaine+Methylphenidate?
>
> Cheers
Im doing the snoozer thing,works wonderfully,so far every time.
Posted by paulbwell on November 3, 2005, at 20:33:34
In reply to Re: NO DOUBT-intranasal Ritalin is quicker, srtonger!!, posted by willyee on November 3, 2005, at 18:43:04
Snorting 20mgs Methylphenidate CAN be a quick and effective way to sober up/improve mood quickly.
Posted by willyee on November 3, 2005, at 22:24:47
In reply to Re: NO DOUBT-intranasal Ritalin is quicker, srtonger!!, posted by paulbwell on November 3, 2005, at 20:33:34
Dude if u ever taken xyrem,and ur on a moderate dose of 2 grams where u have total body and mind relaxation,the ritalin in this way wakes up ur mind only,but leaves ur body at ease,as well as the worry part of ur mind.
It is a POWERFUL combination.I am glad not an option no more as i was becomming indulgent.
Posted by paulbwell on November 3, 2005, at 23:05:43
In reply to Re: NO DOUBT-intranasal Ritalin is quicker, srtonger!!, posted by willyee on November 3, 2005, at 22:24:47
> Dude if u ever taken xyrem,and ur on a moderate dose of 2 grams where u have total body and mind relaxation,the ritalin in this way wakes up ur mind only,but leaves ur body at ease,as well as the worry part of ur mind.
>
>
> It is a POWERFUL combination.I am glad not an option no more as i was becomming indulgent.I hear you dude, a complete full sleep is important, and i suspect that MANY on stimulants-do not get this. They wake up after afew hours sleep and take more stimulants-purpetuating a vicious cycle.
GHB (Xyrem) is reported to be a miracle for some, and if a hard out sleep is acheived, perhaps many would need less stimulants?
being on Ritalin, sleep is interapted-sometimes, leading to the following days not functioning correctly.
Good points
Cheers
This is the end of the thread.
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