Psycho-Babble Medication Thread 558480

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Paxil and augmentation

Posted by denise1966 on September 23, 2005, at 11:18:24

Hi,

Well I'm back on Paxil now 60mg and although I don't feel as weak, I feel incredibly numb and lacking in motivation. I don't want to come off Paxil as at least I'm not an anxious mess on 40mg (any lower and I am)

I'm not going to drop the dose because I've tried that before and it doesn't work.

I know your supposed to give these drugs time but in my experience if they're going to work (for me anyway) they usually work quite fast.

I'll be seeing a psychiatrist soon and I'm going to ask him if I can augment the Paxil with something but not sure what to try with it.

Anyone got any suggestions. I was thinking of one of the following. Although I've already tried Lithium as an add on agent before and it didn't work.

Remeron - High Dose
Effexor - High Dose
T3
Moclobemide
Pindolol
Lithium

Thanks in Advance.........Denise

 

Re: Paxil and augmentation

Posted by blueberry on September 23, 2005, at 19:57:42

In reply to Paxil and augmentation, posted by denise1966 on September 23, 2005, at 11:18:24

I like your thought of adding remeron. It's a completely different mode of action, causing neurotransmitters to be released, as opposed to reuptake inhibitors that just cause them to hang around longer. Remeron releases serotonin at lower doses, then norepinephrine at higher doses, and even dopamine at really high doses. I don't think adding more reuptake inhibition is the way to go. Paxil actually has some fair norepinephrine reuptake inhibition to it.

A stimulant like provigil or ritalin could be a thought as well. Zyprexa is a great add-on to ssri's for apathy, doing similar stuff as remeron but also working on dopamine. Wellbutrin is funky, either helps a lot or sucks a lot.

In any case, I think it would be a good idea to choose meds that work by a totally different mechanism than reuptake inhibition. At your current dose, you already have a ton of that going on.

 

Have you tried Pamelor in conjunction with? (nm) ยป denise1966

Posted by ButterflyHigh on September 27, 2005, at 1:05:11

In reply to Paxil and augmentation, posted by denise1966 on September 23, 2005, at 11:18:24


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