![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by willyee on August 29, 2005, at 13:39:12
Ive researched topamx,for days and days.Understand how crucial the initial dosing is,understand everything about the medication.
However if i bunch all the various groups togther,including this one,and all the general comments period,wow it does NOT come out in favor for topamx.
It seems besides conginitive dullnes which doesent seem to go away,the worst and common side effect from topamax is DEPRESSION.A lot of people not depressed taking it for migraines complain of becomming depressed,it was just a very common trait.So what do i do,no matter how i do the numbers topamax comes in very badly,do i ignore hard evidence and try it anyway?
I can deal with fatigue and dullness,lifting weights is the only thing i have and i cant have a med making me feel weak and sleepy constantly.
Ive tried all the rest,and sinde parnate doesent work very much im thinking to maybe add a stimulant instead,i really dont know.
*PLEASE can anyone tell me if mirapex is a sedative medication or stimulant,i see it works on dopamine but i see its used for rls and i have read people feeling sleepy on it.*I see my doc tommroww and now i have no,zero zilch options in the pipes,i always had one option to try,this is scary.
Posted by ed_uk on August 29, 2005, at 13:55:21
In reply to Now what to do, posted by willyee on August 29, 2005, at 13:39:12
Hi Willy,
I think you'll have to experiment with Topamax and see how you like it. The 15mg sprinkle capsules are useful for titration.
>*PLEASE can anyone tell me if mirapex is a sedative medication or stimulant,i see it works on dopamine but i see its used for rls and i have read people feeling sleepy on it.*
It's not a sedative or a stimulant. Some people find to be effective for depression but it can cause drowsiness and has a reputation for 'pooping out'.
Kind regards
~Ed
Posted by willyee on August 29, 2005, at 14:25:37
In reply to Re: Now what to do » willyee, posted by ed_uk on August 29, 2005, at 13:55:21
Thanks ED,
Let me just give a little idea of what im exper as to what med im looking for....
These are my sympotoms in priority
Diassociation,even when im not depressed i just dont feel the urge to go out and interact,or the urge to go out period.
Obsessivness, not so much in actions i.e washing ones hands,but in thoughts,i dont know the meaning of bored as im always working on something *important* i dont think my mind is capable of unwhining
Hyperactivness, It seems im either up and mmoving around doing this that and the other,or im laying down in depression.
Anxiety, this isnt a huge huge problem as parnate even if its not helping depression usualy helps axniety or klonopin does.Depression, Parnate has pooped out,its effecviness is about 20 percent of what it was,but not wanting to go to any other type of med i dont have any options i been all ssris.
Thanks for reading this,again the getting out of the house thing is the worst,why what is it that keeps me in here,ill make up a project just to JUSTIFY not going out!I also never ever pick up the phone to casualy conversate,these are the symtpoms id be so HAPPY HAPPY to have helped,i know if i can get out of the house and do more every other symptom will be affected in a positive light.
If it isnt full blow anxiety keeping me in,then its my obsseivness nature,thinking that does,as i feel i need this to be cleaned or this to be done etc.
Both stimulants and sedatives have helped in the past i just dont know where to go.
But ED thanks,the sprinkles right,that would be great as i hear the secret to this drug above all other drugs is to introduce it to ur body very slowly.I just hope m doc is familair enough to know how to write a script for it,thank you again.
Posted by ed_uk on August 29, 2005, at 15:07:26
In reply to Re: Now what to do, posted by willyee on August 29, 2005, at 14:25:37
Hi Willy,
I assume you're hoping the Topamax will be pro-social :-)
Do you have a diagnosis? .....one or more.
>But ED thanks,the sprinkles right,that would be great as i hear the secret to this drug above all other drugs is to introduce it to ur body very slowly.
Indeed, the sprinkle capsules are useful for titration. You can get 15mg sprinkle caps and 25mg sprinkle caps.
~Ed
Posted by willyee on August 29, 2005, at 15:46:23
In reply to Re: Now what to do » willyee, posted by ed_uk on August 29, 2005, at 15:07:26
Yess that was exactly my thinking,or should i say hoping.
As far as a diagnonisis,i cant seem to get one,the most i got out of my doc was i dont appear to be bi-polar.When i do ask her she barly looks at me and says...OOOHHHH you just have a really bad case of anxiety.I can only imgaine what disorders i really have.
With the topamax,you asked about it and pro-social,do you find that not to be the case?
I honestly havent seen too much on it for that purpose but even having tried xyrem i dont know how to help myself,i tried everything and nothing can get me out of this house.
I dont know if im lacking gaba or just dont have a full respondendt anti-depressant effect from parnate,i am depressed but i cant determine much since i pyshicaly have trouble leaving the house that alone puts me in a depression.
I asked this group already and got some great responses as to whteht or not they found topamax pro-social.
Posted by Nickengland on August 29, 2005, at 15:47:34
In reply to Re: Now what to do » willyee, posted by ed_uk on August 29, 2005, at 15:07:26
>Indeed, the sprinkle capsules are useful for titration. You can get 15mg sprinkle caps and 25mg sprinkle caps.
Just to add, with the 25mg sprinkle capsules (tiny little balls) there are approximately 206 little balls to each capsule. For the first 2 weeks, everyday I would take a capsule, open it up and divide the 206 into 103 ~ then put 103 into each capsule making them 12.5mg.
After afew days it would only take about 5 minutes to do that and was very much worth it indeed.
Before I tried 25mg tablets and had some cognitive effects, but when using 12.5mg to get to 25mg, those effects were absent.
Kind regards
Nick
Posted by Racer on August 29, 2005, at 17:42:45
In reply to Re: Now what to do, posted by willyee on August 29, 2005, at 15:46:23
>
>
> As far as a diagnonisis,i cant seem to get one,the most i got out of my doc was i dont appear to be bi-polar.When i do ask her she barly looks at me and says...OOOHHHH you just have a really bad case of anxiety.I can only imgaine what disorders i really have.
>It could be that that really is your diagnosis -- Anxiety Disorder, Severe. Your pdoc may not be avoiding the issue, but answering it. Remember, you don't have to have multiple dx, and an anxiety disorder of any sort can be pretty devastating on its own, without inviting any other dxs to the table.
>
>
> I dont know if im lacking gaba or just dont have a full respondendt anti-depressant effect from parnate,i am depressed but i cant determine much since i pyshicaly have trouble leaving the house that alone puts me in a depression.
>I don't think that any medication can get you out of the house, I think that's psychological and behavioral. And that's not meant as anything other than an observation -- I run through periods of intense agoraphobia, where I won't leave the house if I can help it. Meds don't help with that, though. I can be happy and bubbly and generally asymptomatic -- and still not want to leave the house.
Have you tried some therapy? That's the best for me, and it's at least one thing a week that I have to leave the house for, which is a big benefit. At least once a week, I have to shower, dress, put on SHOES, fer cryin' out loud. And once I'm out, I usually do other things, too: run errands, etc.
Can you identify triggers for you outside the house? I know, for instance, where my anxiety about leaving the house comes from. That helps, especially since I know what it will take to help me get past it. If you can identify what your trigger point is, that can help you ease your way back into going out.
Good luck.
Posted by willyee on August 29, 2005, at 19:56:39
In reply to Re: Now what to do » willyee, posted by Racer on August 29, 2005, at 17:42:45
> >
> >
> > As far as a diagnonisis,i cant seem to get one,the most i got out of my doc was i dont appear to be bi-polar.When i do ask her she barly looks at me and says...OOOHHHH you just have a really bad case of anxiety.I can only imgaine what disorders i really have.
> >
>
> It could be that that really is your diagnosis -- Anxiety Disorder, Severe. Your pdoc may not be avoiding the issue, but answering it. Remember, you don't have to have multiple dx, and an anxiety disorder of any sort can be pretty devastating on its own, without inviting any other dxs to the table.
I think that is a very strong possability,in fact i believe in my own view i have anixety,with a dab of ocd/depression/adhd thrown in,but i think anxiety keeps the whole thing spinning.I just wish shed put more time into giving me such a dx,instead of kinda mumbling under her breath.
>
> >
> >
> > I dont know if im lacking gaba or just dont have a full respondendt anti-depressant effect from parnate,i am depressed but i cant determine much since i pyshicaly have trouble leaving the house that alone puts me in a depression.
> >
>
> I don't think that any medication can get you out of the house, I think that's psychological and behavioral. And that's not meant as anything other than an observation -- I run through periods of intense agoraphobia, where I won't leave the house if I can help it. Meds don't help with that, though. I can be happy and bubbly and generally asymptomatic -- and still not want to leave the house.
>
> Have you tried some therapy? That's the best for me, and it's at least one thing a week that I have to leave the house for, which is a big benefit. At least once a week, I have to shower, dress, put on SHOES, fer cryin' out loud. And once I'm out, I usually do other things, too: run errands, etc.
Im too begin therapy soon,i just wish i was pyshicaly better before i start.I know u say theres no med for my problem,but i have had times where i dabbled in combos such as parnate/klonopin/neurtoniton/l theanine/ and a feeling came over me,and as i walked outside i feel better,i felt like CHAIN that was on me had been unleashed,i felt so calm and felt great being out.I know this feeling is in there somewhere,do you really think therpay is the only answer and not any type of chemical adjustment might be needed?
>
> Can you identify triggers for you outside the house? I know, for instance, where my anxiety about leaving the house comes from. That helps, especially since I know what it will take to help me get past it. If you can identify what your trigger point is, that can help you ease your way back into going out.
>
> Good luck.Im very much like u,i awake every single morning,shower get dressed,get breakfast,i can run errands and i can GO OUT,im not house locked.Its just i give up,i dont feel like i wanna face the outside,i have my own little securtiy nest,ah its so hard to put in words,i feel as i said ealrier as if im on some invisable leash and when i try to go forward i feel somthing yank me back.
Luckly i can do it though,i was always able to work,i could subsuide my symptoms,its just i wont go out for enjoyment,only if i have to for errans and such.Its truly ruined my life.
Thanks for the reply!
Posted by jparsell82 on August 29, 2005, at 21:18:54
In reply to Now what to do, posted by willyee on August 29, 2005, at 13:39:12
> Ive researched topamx,for days and days.Understand how crucial the initial dosing is,understand everything about the medication.
>
> However if i bunch all the various groups togther,including this one,and all the general comments period,wow it does NOT come out in favor for topamx.
>
>
> It seems besides conginitive dullnes which doesent seem to go away,the worst and common side effect from topamax is DEPRESSION.A lot of people not depressed taking it for migraines complain of becomming depressed,it was just a very common trait.
>
> So what do i do,no matter how i do the numbers topamax comes in very badly,do i ignore hard evidence and try it anyway?
>
> I can deal with fatigue and dullness,lifting weights is the only thing i have and i cant have a med making me feel weak and sleepy constantly.
>
>
> Ive tried all the rest,and sinde parnate doesent work very much im thinking to maybe add a stimulant instead,i really dont know.
>
>
> *PLEASE can anyone tell me if mirapex is a sedative medication or stimulant,i see it works on dopamine but i see its used for rls and i have read people feeling sleepy on it.*
>
> I see my doc tommroww and now i have no,zero zilch options in the pipes,i always had one option to try,this is scary.
>
>Mirapex was kind of sedating to me. It made me drowsy, not as bad as some other things, but bad enough. I've heard of Mirapex being stimulating to others though.
Also, I read an article on Pubmed awhile back about a couple of people who got relief from treatment-resistant depression with a D2 agonist and Milnacipran. Perhaps you could combine Mirapex with Milnacipran or Cymbalta.
Good luck,
Josh
Posted by Racer on August 29, 2005, at 21:51:24
In reply to Re: Now what to do, posted by willyee on August 29, 2005, at 19:56:39
Yeah, sucks a lot, don't it? There are areas where I can go easily enough -- but they're far from home. It's gotten a lot better lately, though, and you're right: it does kinda require that you're semi-stable on drugs to get more comfortable and motivated about it. Part of my problem is not having my car most days -- long story -- and another is that I really don't have anywhere to go. That sucks, too.
Anyway, I'm glad you're starting therapy. It may not be the only thing that will help you, but I am a very strong believer in therapy as well as meds. It's made a huge difference for me, although I need the meds, too.
{sigh} Guess it would be nice if things were easy, huh?
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.