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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by Cyn523 on August 19, 2005, at 11:30:32
I had never been on anti-depessants previously, and I went on Zoloft, starting at a very small dose (12.5 mg). By the third day on it, I was extremely aggitated, with racing thoughts, talking fast, pacing, etc. There was movement in my peripheral vision. I stopped the drug immediately, and within hours, was restored to my normal state of being. Now, because of that situation, I've been diagnosed as BiPolar II. I thought it took ~6 weeks for anti-depressants to start working on the brain, so how could it induce mania that rapidly? Is it possible this was an ideosyncratic response??? I went on Wellbutrin after I quit the Zoloft. Have been on it for months with no adverse affects. Any thoughts? Thanks!
Posted by ed_uk on August 19, 2005, at 14:27:27
In reply to Zoloft mania, posted by Cyn523 on August 19, 2005, at 11:30:32
Hi Cyn,
>I thought it took ~6 weeks for anti-depressants to start working on the brain, so how could it induce mania that rapidly?
Antidepressants effect the brain within hours of taking the first dose. Side effects such as mania can appear very rapidly. In the treatment of depression, it often takes a few weeks for antidepressants to help..... but the side effects appear much more quickly.
>Now, because of that situation, I've been diagnosed as BiPolar II.
Hmmm. Technically, to be diagnosed BPII, you need to have experienced at least one episode of hypomania which was not drug-induced. Drug-induced manias are highly suggestive of bipolar disorder, but they're not necessarily diagnostic.
>I went on Wellbutrin after I quit the Zoloft. Have been on it for months with no adverse affects.
Mania is less common with Wellbutrin than with Zoloft.
Kind regards
~ed
Posted by linkadge on August 19, 2005, at 15:25:51
In reply to Re: Zoloft mania » Cyn523, posted by ed_uk on August 19, 2005, at 14:27:27
Although it was *possable* that this was a hypomanic episode, I personally doubt it.
All of the SSRI's can cause what is called "start up anxiety", where, for the first few weeks anxiety, agiation, and akathesia are acutely hightened.
I always use this example. If I drink too much coffee, my mind races, I am panicy, and my speech can become more rapid. This, for me is not a manic episode, but more a hightened anxiety produced by the med.
I would question the diagnosis, and consider the possability that this was a start up reaction to the med.
Linkadge
Posted by ed_uk on August 19, 2005, at 15:38:56
In reply to Re: Zoloft mania, posted by linkadge on August 19, 2005, at 15:25:51
>Although it was *possable* that this was a hypomanic episode, I personally doubt it.
Good point Link :-) The talking fast/racing thoughts do sound manic-ish though.
~ed
Posted by Phillipa on August 19, 2005, at 18:26:04
In reply to Re: Zoloft mania » linkadge, posted by ed_uk on August 19, 2005, at 15:38:56
That's what used to happen to me before menopause. Now nothing seems to touch me Fondly, Phillipa
Posted by linkadge on August 19, 2005, at 20:40:21
In reply to Re: Zoloft mania » linkadge, posted by ed_uk on August 19, 2005, at 15:38:56
I see what you are saying. What I say sometimes is more personal oppinion than anything else.
SSRi start up effects for me were similar. Although I was not talking particularly quickly, my mind was racing, and I was very agitated.
It tamed down and nothing became of it.I just encourage people to trust their instincts, and perhaps be informed of other possabilities.
I know that zoloft was certainly more activating for me than celexa.
Linkadge
Posted by MoparFan91 on August 19, 2005, at 20:57:00
In reply to Zoloft mania, posted by Cyn523 on August 19, 2005, at 11:30:32
I took Zoloft 100mg one time over a year ago, and it made me agitated and dysphoric. I took it with 40mg Geodon and 100mg Topamax (which wasn't quite at a therapeutic level). I think something about combining Zoloft with the Geodon triggered those dysphoric manic symptoms. I took Zoloft for 5 weeks, though, and the symptoms started on the 4th week. I think maybe the Zoloft dose was too high and could have been lowered to 50mg, but I discontinued it cold turkey and had bad withdrawal symptoms.
> I had never been on anti-depessants previously, and I went on Zoloft, starting at a very small dose (12.5 mg). By the third day on it, I was extremely aggitated, with racing thoughts, talking fast, pacing, etc. There was movement in my peripheral vision. I stopped the drug immediately, and within hours, was restored to my normal state of being. Now, because of that situation, I've been diagnosed as BiPolar II. I thought it took ~6 weeks for anti-depressants to start working on the brain, so how could it induce mania that rapidly? Is it possible this was an ideosyncratic response??? I went on Wellbutrin after I quit the Zoloft. Have been on it for months with no adverse affects. Any thoughts? Thanks!
Posted by ed_uk on August 20, 2005, at 11:06:55
In reply to Re: Zoloft mania » ed_uk, posted by linkadge on August 19, 2005, at 20:40:21
Hi Link,
Which do you find most activating..... Zoloft or Prozac?
>I just encourage people to trust their instincts, and perhaps be informed of other possabilities.
Everyone with AD side effects seems to be getting diagnosed with BPII at the moment!!!
~ed
Posted by linkadge on August 20, 2005, at 17:02:46
In reply to Re: Zoloft mania » linkadge, posted by ed_uk on August 20, 2005, at 11:06:55
I found zoloft was more activating in terms of psychomotor activity. Prozac seemed more psychologically activating.
Linkadge
Posted by ed_uk on August 21, 2005, at 5:52:03
In reply to Re: Zoloft mania, posted by linkadge on August 20, 2005, at 17:02:46
Hi Link,
That's interesting. Are you saying that Zoloft made you more restless? ........or was it 'activating' in a good way?
Was Prozac good for you? ........or did it make you anxious?
~Ed
Posted by Declan on August 23, 2005, at 0:39:20
In reply to Zoloft mania, posted by Cyn523 on August 19, 2005, at 11:30:32
Hi Cyn
I have a friend who went manic on Zoloft and ended in hospital. She thought the suburb she lived in was on fire. I'm curious about the effect Zoloft had on your peripheral vision. Nothing like flames eh?
Declan
Posted by linkadge on August 24, 2005, at 16:58:22
In reply to Re: Zoloft mania » linkadge, posted by ed_uk on August 21, 2005, at 5:52:03
Prozac gave me strong mental akathesia. I didn't like prozac, it was too sharp.
I think zoloft was the best of the SSRI's, if I had to go back, though I won't.
Linkadge
This is the end of the thread.
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