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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by Jerrympls on May 30, 2002, at 23:52:42
Or should I say - do dr.'s prescribe the two together? and if so - why? (excluding any ADD sympotms - I'm talking about depression only) Does anyone take Ritlain and Dexedrine or Adderall for depression/AD augmentation?
Posted by Hattree on May 31, 2002, at 10:28:47
In reply to Can you take Ritalin w/ Dexedrine?, posted by Jerrympls on May 30, 2002, at 23:52:42
I guess it could be a late-day add-on for after the Dex (long-acting Spansules?) wears off, to get you through the rest of the day. Ritalin is shorter acting than even the immediate-release dex. Just a guess.
Posted by katekite on May 31, 2002, at 12:35:54
In reply to Re: Can you take Ritalin w/ Dexedrine?, posted by Hattree on May 31, 2002, at 10:28:47
I told my pdoc I was taking ritalin to sleep and adderall during the day and he got kind of put out.... said people are not supposed to mix them. I asked him why and he didn't have a good answer. I'm curious if anyone else responds with a reason?
kate
Posted by 3 Beer Effect on May 31, 2002, at 13:51:10
In reply to Can you take Ritalin w/ Dexedrine?, posted by Jerrympls on May 30, 2002, at 23:52:42
I wish I owned or started my own pharmaceutical company since I have so many ideas on how to improve the somewhat dissapointing array of psychiatric medications available out there.
Doctors never prescribe Ritalin & Dex/Adderall together, it is never even mentioned as a possibility in medical literature. Also this combo is never prescribed because these are Schedule II medications tracked/recorded by the DEA & a prescription for two Schedule II ADD drugs to the same person looks suspicious, & also perhaps because the combination might cause an unpredictable rise in blood pressure- in other words the doctor is afraid of liability/malpractice & the DEA.
But, since they act by different mechanisms, if you combined one of the amphetamines- either Dexedrine/Dextrostat or Adderall- AND/WITH RITALIN, taking into account their time to peak blood level (tmax) & duration of action the Dex or Adderall + Ritalin combo would create a "super double whammy" affect on dopamine potentiation!
The reason is that in low to normal dosages the amphetamines Dexedrine/Dextrostat & Adderall primarily RELEASE newly stored/synthesized Dopamine & Norepinphrine into the neuronal space. Ritalin on the other hand, is a dopamine & norepinephrine REUPUTAKE BLOCKER, & fairly similar in its actions to Cocaine (devoid of local anasthetic activity) but superior in that it is much longer lasting, less reinforcing, & is "remarkably non-toxic."
When dopamine & norepinephrine are subject to 'reuputake' into nerve terminals, they are both are destroyed or inactivated by the 'janitorial' enzymes MAO, COM-T, & even the process of reuputake itself.
So if you add Dex & Ritalin together, it is not 1 + 1= 2 but a more potent dopaminergic combination.
Note: if the above explanation is confusing, here is a simple analogy. Imagine you are looking at a reservoir with a dam at the bottom and a stream up top.
Dex/Adderall cause the dopamine/norepinphrine 'stream' to flood, filling the reservoir (the neuronal space) with more 'active' dopamine & norepinephrine.
Ritalin & Cocaine lock all the dam overflow gates & fortify the dam preventing any 'active' "reservoir water" (=dopamine & norepinephrine) from escaping/overflowing the reservoir. When the Ritalin or Cocaine wear off, excess or aged dopamine or norepinephrine escape the resevoir & are killed downstream by evil knife wielding gang-member bandits of the notorious MAO or COMT krews.
The city council might step in & say its time to rid our streets of these evil gangs MAO & COMT.
To do that they bring in one of the big bad super cop anti-gang units called "Parnate, Nardil, or Selegeline/L-Deprenyl". These three anti-gang units wipe out the MAO & COMT gangs quick but then the norepinephrine & dopamine blocks of the city go 'wild in the streets' on their dangerously potentiated Dex/Adderall/Ritalin & form a truce in order to create a bigger, badder, more lethal gang called "hypertension" that attacks the heart of the City causing the power to go out (for good).
3 Beers...........
Posted by ChrisH on May 4, 2005, at 0:32:11
In reply to This combo never prescribed, but great in theory!, posted by 3 Beer Effect on May 31, 2002, at 13:51:10
Do any doctors prescribe the two TOGETHER for ADHD?
Please see here for more discussion : http://groups.google.co.uk/groups?hl=en&lr=&group=alt.support.attn-deficit&selm=1115051085.117972.45440%40l41g2000cwc.googlegroups.com
(that's a link for a google search)
Posted by jerrympls on May 4, 2005, at 22:04:46
In reply to This combo never prescribed, but great in theory!, posted by 3 Beer Effect on May 31, 2002, at 13:51:10
I agree that the two would be a good combo.
Posted by chrish on May 5, 2005, at 13:37:52
In reply to Re: This combo never prescribed, but great in theory! » 3 Beer Effect, posted by jerrympls on May 4, 2005, at 22:04:46
I tried taking both Dexedrine and Ritalin together.
It worked VERY WELL.
I am AMAZED.
I really hope more research is done into this.
Posted by AntRock on May 6, 2005, at 20:42:05
In reply to Re: This combo never prescribed, but great in theo, posted by chrish on May 5, 2005, at 13:37:52
> I tried taking both Dexedrine and Ritalin together.
>
> It worked VERY WELL.
>
> I am AMAZED.
>
>
> I really hope more research is done into this.
Did this combo work well for depression?
If so, could you elaborate?Thanks,
Anthony
>
Posted by chrish on May 9, 2005, at 20:13:04
In reply to Re: This combo never prescribed, but great in theo » chrish, posted by AntRock on May 6, 2005, at 20:42:05
> > I tried taking both Dexedrine and Ritalin together.
> >
> > It worked VERY WELL.
> >
> > I am AMAZED.
> >
> >
> > I really hope more research is done into this.
>
> Did this combo work well for depression?
> If so, could you elaborate?
>
> Thanks,
> Anthony
> >Sorry I don't have depression.
I have ADHD & I am talking about the effects of the medication on ADHD symptoms.
I cannot believe how well it works. I am stunned.
Please post here and on newsgroup: alt.support.attn-deficit if you want to discuss this further.
Posted by Alex Findlay on October 29, 2014, at 8:16:45
In reply to Re: This combo never prescribed, but great in theo, posted by chrish on May 9, 2005, at 20:13:04
I have suffered from devastating depression for almost 50 years. No antidepressant works, but the most effective Triavil. My mother had shock treatment and that helped her. I asked for it but my doc said I will only give you pills .You can stop them but you will live with ECT forever. I have taken Dex Add and Ritalin. Ritalin is good because you skip a day not so with dex. I used dex and Ritalin on the same day sometimes but never together. I took 1 10 mg Dex morning and lunch. That gave me ambition and go. Some nights I was tormented with negative thoughts that simply churned in my head. That is where Ritalin came in. The way it works on dopamine starts to make me think positively in 10 minutes about the next day and blocked all the negatives. Fall right to sleep. The best combination I had was 3 10 mg dex in the day and Nembutal at night. Government here in the US makes some bad decisions. I am sure that the withdrawal of Nembutal has far more harm than good. If you want Nembutal you have to go to Europe. At the same time Europe pulled all Tylenol because of damaging side effects but they are everywhere here. I have been on amphetamines for 42 years with no side effects or bodily harm. The DEA needs to back off and get the illegal stuff off the street and not make peoples life miserable who genuinely need the stuff.
Posted by former poster on November 1, 2014, at 23:49:26
In reply to Re: This combo never prescribed, but great in theo » chrish, posted by Alex Findlay on October 29, 2014, at 8:16:45
Do you think Ritalin is less habit forming than the Dex?
This is the end of the thread.
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