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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 24 of 24. This is the beginning of the thread.
Posted by ace on March 12, 2005, at 23:05:48
Guys,
im having some dental work done and I have to be off nardil...my doc thinks this is good as it will re-start Nardil's euphoric effects which have since gone after, me bing silly, tried clomipramine.....he believes when I restart and regain the euphoric happiness, I should NEVER play with the Nardil dose or dream of getting off it.....
He says stay off it from 3-4 months
But what about withdrawal, depression?????
He doesn't want me on too many other drugs, as this might mitigate Nardil pumping back into big-time euphoric action....in other words, he wants me to clean my drugged brain out
Help!!!!!!!!!!
AceNardil- 60
Lamictal- 200
Seroquel- 150
Xanax- 2mg
Tramadol- 150-250mg PRN
Posted by Phillipa on March 13, 2005, at 0:05:30
In reply to I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!!, posted by ace on March 12, 2005, at 23:05:48
But you're the Champ! Fondly, Phillipa
Posted by SLS on March 13, 2005, at 7:37:21
In reply to I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!!, posted by ace on March 12, 2005, at 23:05:48
What is it about your dental work that would be contraindicated were you to remain on Nardil?
- Scott
Posted by gardenergirl on March 13, 2005, at 13:13:07
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » ace, posted by SLS on March 13, 2005, at 7:37:21
I had some pretty significant work done, including gum surgery while on Nardil. No problems.
Do you have to have a general anesthesia?
gg
Posted by ed_uk on March 13, 2005, at 13:35:29
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!!, posted by gardenergirl on March 13, 2005, at 13:13:07
Hello Andrew,
>Do you have to have a general anesthesia?
If you can find an anesthetist/dentist who is knowledgeable about MAOIs, drug-interactions, which drugs to avoid, pethidine (meperidine) etc, you almost certainly won't need to come off Nardil. The idea than everyone who takes an MAOI needs to come off it before surgery is outdated.
'There is no clinical evidence of dangerous interactions between adrenaline (epinephrine)-containing local anaesthetics and monoamine-oxidase inhibitors (MAOIs)'
“it seems that the use of adrenaline (epinephrine), whether administered in eye drops or as a component of local anaesthesia in dental and other procedures, should not be contraindicated in patients receiving MAOIs.”
Unfortunately, if you can't find an anesthetist/dentist who is knowledgable about MAOIs, you will need to discontinue Nardil.
Here is some information..........
Anaesthetics, general + MAOIs
It is generally recommended that MAOIs should be withdrawn 2 weeks before anaesthesia, although there is some evidence that this may be unnecessary in most patients. However, individual cases of both hypo- and hypertension have been seen and MAOIs can interact dangerously with other drugs sometimes used during surgery (particularly pethidine (meperidine) and ephedrine).
Clinical evidence and mechanism
The absence of problems during emergency general anaesthesia in 2 patients on MAOIs prompted further study in 6 others on long-term treatment with unnamed MAOIs. All 6 were premedicated with 10 to 15 mg of diazepam 2 hours before surgery, induced with thiopental, given suxamethonium (succinylcholine) before intubation, and maintained with nitrous oxide/oxygen with either halothane or isoflurane. Pancuronium was used for muscle relaxation, and morphine was given postoperatively. One patient experienced hypotension that responded to repeated 100-microgram intravenous doses of phenylephrine without hypertensive reactions. No other untoward events occurred either during or after the anaesthesia. 1No adverse reactions occurred in 27 other patients on MAOIs (tranylcypromine, phenelzine, isocarboxazid, pargyline) when anaesthetised. 2 No problems were seen in dogs on tranylcypromine anaesthetised with enflurane and fentanyl and then give the vasopressors noradrenaline (norepinephrine) and ephedrine. 3 Two single case reports describe the safe and uneventful use of propofol in a patient on phenelzine 4 and another on tranylcypromine. 5 The latter was also given alfentanil. No problems were seen in one patient on tranylcypromine when given ketamine 6 and in another on selegiline when given fentanyl, isoflurane and midazolam. 7 No problems were seen in another patient on phenelzine when anaesthetised firstly with sevoflurane in oxygen, followed by isoflurane, oxygen, air and an infusion of remifentanil. 8 Unexplained hypertension has been described in a patient taking tranylcypromine when etomidate and atracurium were used. 9 Moclobemide was stopped on the morning of surgery in a patient who was anaesthetised with propofol and later isoflurane in nitrous oxide and oxygen. Atracurium, morphine and droperidol were also used. No adverse reactions occurred. 10 Ketorolac, propofol and midazolam were used uneventfully in one patient on phenelzine. 11
There are a few anecdotal reports of MAOIs potentiating the effects of amobarbital, butobarbital and secobarbital–see ‘MAOIs + Barbiturates’.
Importance and management
The BNF 12 states that ‘in view of their hazardous interactions MAOIs should normally be stopped 2 weeks before surgery.’ However, there seems to be little documentary evidence that the withdrawal of MAOI before anaesthesia is normally necessary. Scrutiny of reports 13 alleging an adverse reaction usually shows that what happened could be attributed to an interaction between other drugs used during the surgery (e.g. either ‘directly-acting sympathomimetics’ or ‘indirectly-acting sympathomimetics’, or ‘pethidine’) rather than with the anaesthetics. The authors of the reports cited here offer the opinion that . . ‘general and regional anaesthesia may be provided safely without discontinuation of MAOI therapy, provided proper monitoring, adequate preparation, and prompt treatment of anticipated reactions are utilised’. 1,2 This implies that the possible interactions between the MAOI and other drugs are fully recognised, but be alert for the rare unpredictable response.
Regards,
Ed.
Posted by KaraS on March 13, 2005, at 18:34:15
In reply to I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!!, posted by ace on March 12, 2005, at 23:05:48
> Guys,
>
> im having some dental work done and I have to be off nardil...my doc thinks this is good as it will re-start Nardil's euphoric effects which have since gone after, me bing silly, tried clomipramine.....he believes when I restart and regain the euphoric happiness, I should NEVER play with the Nardil dose or dream of getting off it.....
>
> He says stay off it from 3-4 months
>
> But what about withdrawal, depression?????
>
> He doesn't want me on too many other drugs, as this might mitigate Nardil pumping back into big-time euphoric action....in other words, he wants me to clean my drugged brain out
>
>
> Help!!!!!!!!!!
>
>
> Ace
>
> Nardil- 60
> Lamictal- 200
> Seroquel- 150
> Xanax- 2mg
> Tramadol- 150-250mg PRN
Yikes! Sorry to hear that Ace. What does clomipramine have to do with it? Were you adding clomipramine onto your Nardil? Isn't that dangerous? While you've been on the Nardil recently were you feeling depressed or just not euphoric? It seems to me that aiming for constant euphoria is unrealistic. (At this point I'd settle for tolerable so I'm probably the wrong person to comment here.)Anyhow, I hope that your doctor's plan works (we'll want our Nardil champ back!) and that you make it through the next 3-4 months ok.
Will be thinking of you...
Kara
Posted by Maxime on March 13, 2005, at 20:58:54
In reply to I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!!, posted by ace on March 12, 2005, at 23:05:48
Ace, when did you start taking Lamictal? Just curious. Were you taking the clomipramine because it is good for OCD?
No, I can't imagine you not taking Nardil for 3-4 months. That is just wrong.
Can you define euphoric? You use that term a lot but maybe it's just an expression you use. :)
What are you going to do?
Maxime
> Guys,
>
> im having some dental work done and I have to be off nardil...my doc thinks this is good as it will re-start Nardil's euphoric effects which have since gone after, me bing silly, tried clomipramine.....he believes when I restart and regain the euphoric happiness, I should NEVER play with the Nardil dose or dream of getting off it.....
>
> He says stay off it from 3-4 months
>
> But what about withdrawal, depression?????
>
> He doesn't want me on too many other drugs, as this might mitigate Nardil pumping back into big-time euphoric action....in other words, he wants me to clean my drugged brain out
>
>
> Help!!!!!!!!!!
>
>
> Ace
>
> Nardil- 60
> Lamictal- 200
> Seroquel- 150
> Xanax- 2mg
> Tramadol- 150-250mg PRN
Posted by Sarah T. on March 13, 2005, at 23:51:38
In reply to I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!!, posted by ace on March 12, 2005, at 23:05:48
Hi ace. When I was on Parnate, another MAOI, I told the dentist that I was on an MAOI and needed an anesthetic that did NOT contain sympathomimetic vasoconstrictors. The dentist had another anesthetic available, but I can't remember the name of it. I had to go through the same rigmarole when I had some things biopsied at the dermatologist. My dermatologist also had alternate anesthestics available.
Posted by ed_uk on March 15, 2005, at 9:17:14
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » ace, posted by Sarah T. on March 13, 2005, at 23:51:38
Hello :-)
Epinephrine (adrenaline) is the most popular sympathomimetic vasoconstrictor in dentistry. Certain vasoconstrictors can interact dramatically with MAOIs, mainly indirecly-acting sympathomimetics such as phenlypropanolamine. Fortunately, the interaction between epinephrine and MAOIs is apparantly quite minor. Epinephrine is a directly-acting sympathoimetic. It is important to remember than directly-acting sympathomimetics have a different mechanism of action to indirectly-acting sympathomimetics. In lists of drug interactions, there has been a tendency to lump all sympathomimetics together- as if they were all the same, but they are not!! It is commonly assumed that epinephrine is dangerous, this is solely due to reports of interactions between MAOIs and other sympathomimetics which have a different mechanism of action, there haven't been any reports of serious interactions between epinephrine and MAOIs.
From Stockely's Interactions....
The pressor effects of epinephrine (adrenaline), isoprenaline (isoproterenol), norepinephrine (noradrenaline) and methoxamine may be unchanged or only moderately increased in patients taking MAOIs. The increase may be somewhat greater in those who show a significant hypotensive response to the MAOI.
Clinical evidence
(a) Effects in the absence of MAOI-induced hypotensionTwo subjects given phenelzine (Nardil) 15 mg three times daily and another given tranylcypromine (Parnate) 10 mg three times daily for 7 days showed no significant changes in their pressor responses to either epinephrine (adrenaline) or isoprenaline (isoproterenol).
Yet another study in 3 healthy subjects given tranylcypromine (Parnate) found that the effects of norepinephrine were slightly increased, while with epinephrine a two to four fold increase in the effects on heart rate and diastolic pressure took place, but a less marked increase in systolic pressure.
A patient using 1% epinephrine eye drops twice daily showed no increase in blood pressure or heart rate when treated with tranylcypromine (Parnate) 20 mg, rising to 50 mg daily.
Mechanism
These directly-acting sympathomimetic amines act directly on the receptors at the nerve endings, which innervate arterial blood vessels, so that the presence of the MAOI-induced accumulation of norepinephrine within these nerve endings would not be expected to alter the extent of direct stimulation. The enhancement seen in those patients whose blood pressure was lowered by the MAOI might possibly be due to an increased sensitivity of the receptors, which is seen if the nerves are cut, and is also seen during temporary ‘pharmacological severance’.Importance and management
The evidence is limited, but the overall picture is that some slight to moderate enhancement of the effects of norepinephrine (noradrenaline) and epinephrine (adrenaline) may occur in patients who do not show MAOI-induced hypotension. However, the authors of three of the reports cited 1,3,4 are in broad agreement that problems are unlikely to occur. One group 4 says that “it seems that the use of epinephrine, whether administered in eye drops or as a component of local anaesthesia in dental and other procedures, should not be contraindicated in patients receiving MAOIs.”The situation in patients who show a reduced blood pressure due to the use of an MAOI is less clear. One study found an increase in the pressor efforts of norepinephrine and methoxamine in hypertensive patients on pheniprazine or tranylcypromine (Parnate), whereas another 10 found no changes in the pressor effects of norepinephrine in patients on pargyline.
>The dentist had another anesthetic available, but I can't remember the name of it.Prilocaine + felypressin.........
Felypressin is a vasocontrictor which is used in dentistry. In the UK, it is available for dental use in combination with the local anesthetic prilocaine. The brand name is 'Citanest with Octapressin'.
Best regards,
Ed.
Posted by ace on March 15, 2005, at 17:49:28
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » ace, posted by SLS on March 13, 2005, at 7:37:21
> What is it about your dental work that would be contraindicated were you to remain on Nardil?
>
>
> - ScottI was in a haze when i saw the doctor. I have an infected molar which has turned into an abcess....also the infection has spread through the bloodstream causing general malaise.
He mentioned some drug....I forgot.
But he unequivocally stated Nardil MUST be ceases.
He said on the upside, he believes we will regain the euphoric effects on reinstistution, provided I remove some other drugs from my cocktail....
Ace!
Posted by ace on March 15, 2005, at 17:50:09
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!!, posted by gardenergirl on March 13, 2005, at 13:13:07
> I had some pretty significant work done, including gum surgery while on Nardil. No problems.
>
> Do you have to have a general anesthesia?
>
> ggBelieve so! I'm not a happy chappy!!!
Ace!
Posted by ace on March 15, 2005, at 17:50:45
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!!, posted by ed_uk on March 13, 2005, at 13:35:29
Posted by ace on March 15, 2005, at 17:57:35
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » ace, posted by KaraS on March 13, 2005, at 18:34:15
> > Guys,
> >
> > im having some dental work done and I have to be off nardil...my doc thinks this is good as it will re-start Nardil's euphoric effects which have since gone after, me bing silly, tried clomipramine.....he believes when I restart and regain the euphoric happiness, I should NEVER play with the Nardil dose or dream of getting off it.....
> >
> > He says stay off it from 3-4 months
> >
> > But what about withdrawal, depression?????
> >
> > He doesn't want me on too many other drugs, as this might mitigate Nardil pumping back into big-time euphoric action....in other words, he wants me to clean my drugged brain out
> >
> >
> > Help!!!!!!!!!!
> >
> >
> > Ace
> >
> > Nardil- 60
> > Lamictal- 200
> > Seroquel- 150
> > Xanax- 2mg
> > Tramadol- 150-250mg PRN
>
>
> Yikes! Sorry to hear that Ace. What does clomipramine have to do with it? Were you adding clomipramine onto your Nardil?
No no. When I was on Nardil it was the bomb, just breathtaking AD effects. Unfortunately I stupidlt stopped Nardil to try Clomipramine. I went back on Nardil, and the euphoria cycled in and out until, it turned into just a steady happiness. Now it is doing even less and less. The Nardil champ is not happy!!
Isn't that dangerous? While you've been on the Nardil recently were you feeling depressed or just not euphoric?Depressed at times. And I'm on 4 drugs!!! Not good enough. I think I have to give Nardil a break, give it time to get the euphoria back, and then institute a small dose (0.5) of Risperidone. Only Antipsychotics work for my oCD. I remember those fond days...I was so so so so so so happy and content...and i was only on 1 drug!!!! My MD thinks the interactions between all my drugs now isn't helping....i agree.
It seems to me that aiming for constant euphoria is unrealistic.
I probably use the word euphoria wrongly in a clinically sense. I just feel EXTEMELY happy, content, confidend and outgoing on Nardil when it is at its peak. Sometimes now I cry when I think of those happy times, and yearn for them to return.
(At this point I'd settle for tolerable so I'm probably the wrong person to comment here.)
>
> Anyhow, I hope that your doctor's plan works (we'll want our Nardil champ back!) and that you make it through the next 3-4 months ok.That's the plan -- 3-4 months off. Also drop everything except Xanax and institute Risperidone.
Euphoria will come back. My doctor is very certain of this.
God Bless you and peace to you!!!!
Ace
>
> Will be thinking of you...
> Kara
>
Posted by ace on March 15, 2005, at 18:02:48
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!, posted by Maxime on March 13, 2005, at 20:58:54
> Ace, when did you start taking Lamictal?
Hmmm...3 months or so ago. It was initially very good for depression.
Just curious. Were you taking the clomipramine because it is good for OCD?
I tried it 3 or 4 times - could not make it past the third day on it, due to it making my symptoms much worse.
>
> No, I can't imagine you not taking Nardil for 3-4 months. That is just wrong.Its hard. But i think this is the only way to regain those intense feelings of CONSTANT happiness.
>
> Can you define euphoric? You use that term a lot but maybe it's just an expression you use. :)Yeah. It is probably not really euphoria. It is just a feeling of COMPLETE and UTTER happiness, confidence, calm, and bliss. I remember I used to chat to so many girls and feel so much love for everyone on Nardil -- that has kind of gone (although I love all you guys forever). The only time I felt annoyed when the Nardil was at its peak was when I had to go to sleep -- because I couldn't wait for the next day!!!!!!
>
> What are you going to do?Drop Nardil for 4 months. Drop Lamictal. Keep Xanax. Institute Risperidone at .5mg. Basicall 'clean' my brain out and step away and let Nardil return in full flight.
>
> MaximeYou take care Maxime!
Ace
>
>
>
> > Guys,
> >
> > im having some dental work done and I have to be off nardil...my doc thinks this is good as it will re-start Nardil's euphoric effects which have since gone after, me bing silly, tried clomipramine.....he believes when I restart and regain the euphoric happiness, I should NEVER play with the Nardil dose or dream of getting off it.....
> >
> > He says stay off it from 3-4 months
> >
> > But what about withdrawal, depression?????
> >
> > He doesn't want me on too many other drugs, as this might mitigate Nardil pumping back into big-time euphoric action....in other words, he wants me to clean my drugged brain out
> >
> >
> > Help!!!!!!!!!!
> >
> >
> > Ace
> >
> > Nardil- 60
> > Lamictal- 200
> > Seroquel- 150
> > Xanax- 2mg
> > Tramadol- 150-250mg PRN
>
>
Posted by ace on March 15, 2005, at 18:03:27
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » ace, posted by Sarah T. on March 13, 2005, at 23:51:38
Posted by ace on March 15, 2005, at 18:04:09
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » Sarah T., posted by ed_uk on March 15, 2005, at 9:17:14
Posted by SLS on March 15, 2005, at 19:16:19
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » SLS, posted by ace on March 15, 2005, at 17:49:28
Hi Ace.
> I was in a haze when i saw the doctor. I have an infected molar which has turned into an abcess....also the infection has spread through the bloodstream causing general malaise.
>
> He mentioned some drug....I forgot.
>
> But he unequivocally stated Nardil MUST be ceases.
>
> He said on the upside, he believes we will regain the euphoric effects on reinstistution, provided I remove some other drugs from my cocktail....
If you are lucky, you'll experience a Nardil-discontinuation rebound improvement that will last for a couple weeks. Things won't be so horrendous if you do. I hope you are predisposed to this phenomenon. I don't know how common it is, but I will be interested to see if it happens to you.
- Scott
Posted by Tepiaca on March 15, 2005, at 20:18:07
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » ace, posted by SLS on March 15, 2005, at 19:16:19
> If you are lucky, you'll experience a Nardil-discontinuation rebound improvement that will last for a couple weeks. Things won't be so horrendous if you do. I hope you are predisposed to this phenomenon. I don't know how common it is, but I will be interested to see if it happens to you.
>
>
> - ScottI have had this rebound improvement Scott , it lasted 10 days. But the real and best improvement was when I re-started the Nardil at 30mg. It was amazing. Sadly this effect only lasted for a week. I have in my future plans to pratice this continously. Do you believe thi is dangerous??
Posted by Tepiaca on March 15, 2005, at 20:21:04
In reply to I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!!, posted by ace on March 12, 2005, at 23:05:48
Hey champion Ace, just to let you know . I had a serious surgery in one of my feets. My doctors used a local anesthesy and I did not have to stop taking the Nardil . There was no interaction at all. Unfortunately I dont remeber which is the anesthesy they used on me.Good luck in your new experiment !
Posted by SLS on March 16, 2005, at 5:51:49
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » SLS, posted by Tepiaca on March 15, 2005, at 20:18:07
>
> > If you are lucky, you'll experience a Nardil-discontinuation rebound improvement that will last for a couple weeks. Things won't be so horrendous if you do. I hope you are predisposed to this phenomenon. I don't know how common it is, but I will be interested to see if it happens to you.
> >
> >
> > - Scott
>
> I have had this rebound improvement Scott , it lasted 10 days. But the real and best improvement was when I re-started the Nardil at 30mg. It was amazing. Sadly this effect only lasted for a week. I have in my future plans to pratice this continously. Do you believe thi is dangerous??
I hope not! I'm considering doing it myself!Good luck. I don't think it is dangerous. However, be wary of diminishing returns. If you start losing the effect, either continue taking it or stop it and move on. You don't want to make yourself more treatment-resistent than you already are. "Pulsing" antidepressants can to that.
- Scott
Posted by ed_uk on March 16, 2005, at 9:25:38
In reply to Re: I have to go off Nardil! NO!!!!!!!!!!!!!!!!!!!!! » gardenergirl, posted by ace on March 15, 2005, at 17:50:09
Hi Andrew,
Didn't you stop Nardil before and get ill? I'm a bit worried.
Ed.
Posted by ace on March 17, 2005, at 20:51:05
In reply to Ace is d/cing Nardil!!!!!!!!! » ace, posted by ed_uk on March 16, 2005, at 9:25:38
> Hi Andrew,
>
> Didn't you stop Nardil before and get ill? I'm a bit worried.
>
> Ed.Thanks man for your concern...when i stopped it before i got very ill....this time when i stop it I have lamicatl, seroquel and Xanax top 'protect' me. I'm not looking foward to going off it. but on the positive side, my doctor firmly believes that once we spend enough time off it, and then we start it again -- it will work BETTER THAN EVER! Euphoria and tranquility and content feeling, and confidence all the time!!!!!
Wish me luck my brother, and thanks so much for your concern again,
Peace,
Andrew
>
>
Posted by Maxime on March 20, 2005, at 18:55:07
In reply to Re: Ace is d/cing Nardil!!!!!!!!! » ed_uk, posted by ace on March 17, 2005, at 20:51:05
Ace, I can't remember if you actually suffer from depression or if it is OCD and social anxiety. Because if you have depression I am so worried that Lamictal is not going to cut it. Do you have a back up plan?
Maxime
> > Hi Andrew,
> >
> > Didn't you stop Nardil before and get ill? I'm a bit worried.
> >
> > Ed.
>
> Thanks man for your concern...when i stopped it before i got very ill....this time when i stop it I have lamicatl, seroquel and Xanax top 'protect' me. I'm not looking foward to going off it. but on the positive side, my doctor firmly believes that once we spend enough time off it, and then we start it again -- it will work BETTER THAN EVER! Euphoria and tranquility and content feeling, and confidence all the time!!!!!
>
> Wish me luck my brother, and thanks so much for your concern again,
>
> Peace,
> Andrew
>
>
> >
> >
>
>
Posted by ace on March 21, 2005, at 21:38:25
In reply to Re: Ace is d/cing Nardil!!!!!!!!! » ace, posted by Maxime on March 20, 2005, at 18:55:07
> Ace, I can't remember if you actually suffer from depression or if it is OCD and social anxiety. Because if you have depression I am so worried that Lamictal is not going to cut it. Do you have a back up plan?
Lamictal is a tricky one. I remember going from 200mg to 150mg....depression set in. My back up plan is basically just to stay on Xanax and quickly bring Risperidone in the picture (for OC, and hopefully depression). My doctor wants to "wash my brain out". He thinks that is why Nardil stopped producing euphoric effect -- due to post-synaptic receptors being pushed to the max all over the place. He is absolutely sure after a four month break Nardil we be back to brilliance -- and it will stay this way unless I stupidly stop and start it (like last time)Thanks heaps for your concern, and God Bless you,
Peace,
Ace (Andrew)
>
> Maxime
>
>
>
> > > Hi Andrew,
> > >
> > > Didn't you stop Nardil before and get ill? I'm a bit worried.
> > >
> > > Ed.
> >
> > Thanks man for your concern...when i stopped it before i got very ill....this time when i stop it I have lamicatl, seroquel and Xanax top 'protect' me. I'm not looking foward to going off it. but on the positive side, my doctor firmly believes that once we spend enough time off it, and then we start it again -- it will work BETTER THAN EVER! Euphoria and tranquility and content feeling, and confidence all the time!!!!!
> >
> > Wish me luck my brother, and thanks so much for your concern again,
> >
> > Peace,
> > Andrew
> >
> >
> > >
> > >
> >
> >
>
>
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
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