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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by TomG on March 16, 2005, at 16:45:42
Yesterday was day 8 of Seroquel 50mgs. By the end of the day yesterday I was having way more positive, focused, oraganized thought. The bad thing is I kinda feel like the times I've had some very mild hypomania. I'm still sleeping like Rip Van Winkle and I kinda feel sleepy today, but the hangover stoned feeling I was having the first week seems to be gone. Surely Seroquel couldn't cause hypomania. I'm hoping that raising the dose to 100 or 150mgs will yeild positive results. I don't know if I should call my doctor now or wait until April 8th until I see him next.
I responded really positively to Geodon 20mgs for about two months and it kinda lost alot of its spark. However, it started working within 1 day! I looked back at a really old post of mine when I tried Zyprexa for the first time and I said that I responded to 2.5mgs or it might have been the Lamictal that I was taking at the time. I wasn't able to tell which drug it was that was working. I then raised the Zyprexa to 5mgs and sort of lost effect. I was thinking that maybe I only respond to really low doses of AP's. I've tried Zyprexa all the way up to 15mgs and it really didn't do anything for me. Can AP's work at really low dose and prove ineffective at high dose? If the Seroquel is working right now it doesn't have quite the kick that Geodon had. Again maybe that can be affected by a dosage change. Wish me luck.
Posted by med_empowered on March 16, 2005, at 19:36:12
In reply to Seroquel Might Be Working, posted by TomG on March 16, 2005, at 16:45:42
hey! Glad you're feeling better! If you have a problem with med-induced hypomania/mania/mixed-episodes, you may want to be somewhat cautious with atypical antipsychotics. Strange, but true: it appears that some may induce hypomania/mania in some people. I've mostly heard about it re: Abilify, but, given the complex pharmacological properties of the atypicals, its worth monitoring. Some people will respond nicely to low/mini-dose antipsychotics and then lose the "oomph" as the dose is increased. The only thing I can compare it to is some studies with schizophrenics which found that sometimes mini-doses of both old and new antipsychotics work quite well on negative symptoms with minimal side-effects; as the dosage was increased to more "standard" levels, there was less of an effect on negative symptoms but more of one on positive symptoms; in addition, side-effects increased. If you're not actively suicidal, its certainly worth trying a mini-dose.
Posted by PM80 on March 17, 2005, at 14:22:06
In reply to Seroquel Might Be Working, posted by TomG on March 16, 2005, at 16:45:42
> Yesterday was day 8 of Seroquel 50mgs. By the end of the day yesterday I was having way more positive, focused, oraganized thought. The bad thing is I kinda feel like the times I've had some very mild hypomania. I'm still sleeping like Rip Van Winkle and I kinda feel sleepy today, but the hangover stoned feeling I was having the first week seems to be gone. Surely Seroquel couldn't cause hypomania. I'm hoping that raising the dose to 100 or 150mgs will yeild positive results. I don't know if I should call my doctor now or wait until April 8th until I see him next.
>
> I responded really positively to Geodon 20mgs for about two months and it kinda lost alot of its spark. However, it started working within 1 day! I looked back at a really old post of mine when I tried Zyprexa for the first time and I said that I responded to 2.5mgs or it might have been the Lamictal that I was taking at the time. I wasn't able to tell which drug it was that was working. I then raised the Zyprexa to 5mgs and sort of lost effect. I was thinking that maybe I only respond to really low doses of AP's. I've tried Zyprexa all the way up to 15mgs and it really didn't do anything for me. Can AP's work at really low dose and prove ineffective at high dose? If the Seroquel is working right now it doesn't have quite the kick that Geodon had. Again maybe that can be affected by a dosage change. Wish me luck.
I don't know much about the other medications you've listed, but I am on Seroquel. The dose definitely makes a difference. Lower doses didn't work well for me-I was somewhat hypomanic and still had panic attacks, but now I am on 300mg/day and my anxiety (and panic attacks) is completely gone, I sleep better, and I don't have those uncomfortable racing thoughts. For daytime, the drowsiness factor won't be as bad if you take it on an empty stomach. At least that's been my experience with Seroquel.
This is the end of the thread.
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