Psycho-Babble Medication Thread 466710

Shown: posts 1 to 25 of 30. This is the beginning of the thread.

 

Does Norepinephrine cause anxiety?

Posted by MM on March 4, 2005, at 21:20:14

I don't mean to repeat myself, but I am thinking there are people on the board who might know the answers to my questions but just aren't reading my posts because I'm not labeling them correctly. I am wondering if Wellbutrin causes anxiety because of the increase in norepinephrine, yet helps with depression because of the increase in dopamine. Does anyone know what it specifically does? Like at lower doses does it only effect one of them or anything like that? I'm sorry if my questions seem really simple or something but I have looked and haven't found the answer so...
MM

 

Re: Does Norepinephrine cause anxiety?

Posted by lunesta on March 4, 2005, at 22:53:54

In reply to Does Norepinephrine cause anxiety?, posted by MM on March 4, 2005, at 21:20:14

in short, your answer is yes. norep. does cause increased anxiety when released... most stimulants do. at very high dosages they can cause euphornia because of dopamine release.

wellbutrin is defintely known to cause anxiety!

 

Re: Does Norepinephrine cause anxiety? » MM

Posted by Ritch on March 5, 2005, at 0:37:54

In reply to Does Norepinephrine cause anxiety?, posted by MM on March 4, 2005, at 21:20:14

> I don't mean to repeat myself, but I am thinking there are people on the board who might know the answers to my questions but just aren't reading my posts because I'm not labeling them correctly. I am wondering if Wellbutrin causes anxiety because of the increase in norepinephrine, yet helps with depression because of the increase in dopamine. Does anyone know what it specifically does? Like at lower doses does it only effect one of them or anything like that? I'm sorry if my questions seem really simple or something but I have looked and haven't found the answer so...
> MM


I couldn't enlighten you as to what WB is *actually* doing.. but my experience with it (over several years, at lower, higher dosages, and with combos with other meds) is that it seems to mimic the noradrenergic (norepi) effects of stimulants. It reminds me of how I felt when I took phentermine (a weight loss drug). It *doesn't* feel much like dexedrine or methylphenidate to me. There is an effect that felt a *little* like Adderall (the l-isomers??- who knows?). There is a sister drug to WB that's called Didrex (I think) which IS a weight-loss med. WB breaks down to active metabolites which have different effects than the parent drug. It seemed like every time I *retried* WB it always seemed to work really well for a couple of weeks or so, then my anxiety started going up slowly but surely a lot thereafter. I developed fear of heights that I never had before, etc. So... I think that I could say that norepi tends to *cause* VIGILANCE, and that individual folks may get worsened anxiety as a result of their subjective interpretation of that vigilance.. just a guess. I haven't heard diddly about someone who had panic disorder and found WB to work wonders for their panic disorder.... Norepinephrine reuptake inhibitors such as desipramine, nortriptyline, etc. *are* good for panic disorder and they do increase norepi which leads to down-regulation of adrenoreceptors ... maybe WB doesn't do that and that's why it is lousy for panic?

 

Re: Does Norepinephrine cause anxiety? » Ritch

Posted by MM on March 5, 2005, at 0:53:55

In reply to Re: Does Norepinephrine cause anxiety? » MM, posted by Ritch on March 5, 2005, at 0:37:54

So what you're saying is that it kind of depends on how you manipulate the norepinephrine?

This vigilance might be some of what I'm experiencing. I'm more socially paranoid, like vigilant about everything I say and do, am over-analyzing etc. and am having sort of freak out sessions where I can't handle anything and am tearful...a little like a panick attack but not quite. This stuff I noticed started to happen with an increased dose (to 150mg from 75mg) (but my pdoc is pretty into the SAD thing so I'm wondering if increase in daylight hours has something to do with it too?). I still am more comfortable (to a point) taking Wellbutrin than an SSRI though. So what the !$#& do I do now that neither one seems to work? (Neither does Serzone, which I think is an SNRI?)...I'm in the process, or trying to get into the process of changing my pdoc and I am feeling like it's all pretty hopeless and I dunno what to do. Just disregard my babbling. Thanks for the reply, Ritch (did you used to post under Mitch?).
MM

 

Re: Does Norepinephrine cause anxiety?

Posted by temoigneur on March 5, 2005, at 1:49:33

In reply to Re: Does Norepinephrine cause anxiety? » MM, posted by Ritch on March 5, 2005, at 0:37:54

Thought I'd just chime in with my personal experience. It's so frustrating that psychiatric understanding of the mechanisms by which some of these drugs work, is so crudely understood, or not understood at all. I have taken every SSRI, SSRI + Antipsychotic, SNRI's and now 2 tricylics. Effexor made me very anxious, as did a related anaglesic, tramadol. It's hard to say what was doing what, as I went frantic, when bumped up to 80mg Prozac too. I have my psychiatric records, and one doctor noted, that I did experience an increase in anxiety with the trial of noradrenergic medications along with development of motor neuron tics Now, on clomipramine, I have virtually no anxiety, but total apathy/anhedonia, foggy mind, I hate it, if anyone has any suggestion for something I might take to counter this, (had the same foggy head with imipramine) I would be grateful.

Ben

 

Are those the choices? » temoigneur

Posted by MM on March 5, 2005, at 2:01:20

In reply to Re: Does Norepinephrine cause anxiety?, posted by temoigneur on March 5, 2005, at 1:49:33

Total apathy OR crippling anxiety? Or those to some degree, but not a functional balance....?? I don't think so but, well I hope not, and some people do seem to find that magic combo or med. See I'm trying to figure out what brain chemicals/neurotransmitters do what; what meds do what to what chemicals/transmitters; what to take and how to combine it to make my brain work the way I want to...which is probably what every one is doing here too (sometimes I feel too ignorant to be here though). Wish I could recommend something Ben...all I can think of is low doses of each kind of med? But I dunno what that would do...Hopefully someone who does know will read your posts and help out. Good luck.
MM

 

Re: Does Norepinephrine cause anxiety?

Posted by SLS on March 5, 2005, at 7:53:20

In reply to Re: Does Norepinephrine cause anxiety? » MM, posted by Ritch on March 5, 2005, at 0:37:54

When treating depression, desipramine, a selective NE reuptake inhibitor, can be anxiolytic. In healthy people, it can be sedating. Strattera, another selective NE reuptake inhibitor is virtually free of producing anxiety. It, too, can be sedating and anxiolytic. Sometimes, it isn't productive to generalize drug effects based upon what little we understand about them and how the brain works.

- Scott

 

Re: Does Norepinephrine cause anxiety? » SLS

Posted by Dinah on March 5, 2005, at 8:30:50

In reply to Re: Does Norepinephrine cause anxiety?, posted by SLS on March 5, 2005, at 7:53:20

Does that mean I ought not to be so quick to rule out anything that acts on NE? I did very very badly on Effexor/Wellbutrin/Nortriptyline. So much so that I've come to view NE as poison for *me*.

But are you saying there could be NE affecting drugs that don't send me to jittery, itchy-crawly, akasthesia h*ll? Might Cymbalta or another tricyclic be ok?

 

Re: Does Norepinephrine cause anxiety? » Dinah

Posted by SLS on March 5, 2005, at 9:30:23

In reply to Re: Does Norepinephrine cause anxiety? » SLS, posted by Dinah on March 5, 2005, at 8:30:50

Hi Dinah.

> Does that mean I ought not to be so quick to rule out anything that acts on NE? I did very very badly on Effexor/Wellbutrin/Nortriptyline.

Were your reactions to these 3 drugs exactly the same? If not, what were the differences? How long did you take each of these drugs?

> So much so that I've come to view NE as poison for *me*.

It indeed might be, but given the cost to you of not exploring new drugs, it probably make sense for us to act less like brilliant neuropsychopharmacologists and more like patients, although playing the part of the former is much more fun. Experimentation is a necessary evil here.

> But are you saying there could be NE affecting drugs that don't send me to jittery, itchy-crawly, akasthesia h*ll?

Yes.

How does amphetamine (Dexedrine or Adderall) affect you?

> Might Cymbalta or another tricyclic be ok?

Arghhh! I don't know. :-( I wish I did. Sorry.

I am disappointed to hear that nortriptyline gave you so much trouble. I would say that anxiety can be a passing side effect and generally resolves within a week or two. Toss Wellbutrin out for the moment. Effexor and nortriptyline both exert pro-serotonergic effects. Desipramine does not. It might be interesting to see how taking a drug that doesn't mix NE and 5-HT reuptake inhibition would affect you.

Do you avoid entirely those drugs that have the potential to produce weight gain?

Which SSRI did you find to be the most helpful?

Whichever one it is, add Remeron and lithium to it and play with Lamictal if necessary.

No way, huh?

:-)


- Scott

 

Re: Does Norepinephrine cause anxiety? » MM

Posted by Ritch on March 5, 2005, at 9:34:21

In reply to Re: Does Norepinephrine cause anxiety? » Ritch, posted by MM on March 5, 2005, at 0:53:55

> So what you're saying is that it kind of depends on how you manipulate the norepinephrine?
>
> This vigilance might be some of what I'm experiencing. I'm more socially paranoid, like vigilant about everything I say and do, am over-analyzing etc. and am having sort of freak out sessions where I can't handle anything and am tearful...a little like a panick attack but not quite. This stuff I noticed started to happen with an increased dose (to 150mg from 75mg) (but my pdoc is pretty into the SAD thing so I'm wondering if increase in daylight hours has something to do with it too?). I still am more comfortable (to a point) taking Wellbutrin than an SSRI though. So what the !$#& do I do now that neither one seems to work? (Neither does Serzone, which I think is an SNRI?)...I'm in the process, or trying to get into the process of changing my pdoc and I am feeling like it's all pretty hopeless and I dunno what to do. Just disregard my babbling. Thanks for the reply, Ritch (did you used to post under Mitch?).
> MM

Yep, it's Mitch (computer messed up long ago, re-registered). Anyhow.. yes I *think* that it is generally how norepi is *handled* or how your body reacts to its effects specifically with WB and how it seems to be much more so anxiogenic than the other "norepi" meds. The last time I was on WB, I decided I was going to work the dose up gradually and just tough it out and see if things would settle down and they didn't. I remember being in a store and a grandfather and grandchild were playing and he was getting tossed up in the air near a glass display case and I freaked out and catastrophized the whole event in my mind (calling 911, helping to pull glass out of people, the whole nine yards) that I avoided the entire area and walked around it.. Way over the top. You said you are getting a new doctor, so maybe you can get some better insights into which med would work for you better.. be sure to relate all this to the new doc so you don't get stuck on something again that didn't work. You didn't mention any TCA's or Effexor or Cymbalta. You might consider one of those. Hope this helps.

 

Re: Does Norepinephrine cause anxiety? » SLS

Posted by ed_uk on March 5, 2005, at 10:54:21

In reply to Re: Does Norepinephrine cause anxiety?, posted by SLS on March 5, 2005, at 7:53:20

Hi Scott,

>When treating depression, desipramine, a selective NE reuptake inhibitor, can be anxiolytic.

Yes, this is true. Desipramine can be useful in panic disorder as well.

As you said earlier, no one really understands the mechanism of action of Wellbutrin. No one knows why Wellbutrin seems to cause anxiety for so many people, it might have nothing at all to do with norepinephrine. People often call Wellbutrin 'noradrenergic' or 'dopaminergic' but it is only a weak uptake inhibitor of norepinephrine and it's effect on dopamine uptake is so small that it may be insignificant. It's possible that the mechanism of action of Wellbutrin has little to do with either norepinephrine or dopamine. Alternatively, it could be affecting these amines in as yet unidentified ways.

Ed.

 

Re: Does Norepinephrine cause anxiety?

Posted by sabre on March 5, 2005, at 12:53:41

In reply to Does Norepinephrine cause anxiety?, posted by MM on March 4, 2005, at 21:20:14

Hello MM
I started Reboxetine, a pure noradrenaline reuptake inhibitor, a week ago. I took 1mg (!) twice a day and the next day another 1 mg (+ propranolol). I delivered a work presentation of a few minutes - reading from notes - and suffered no anticipatory or performance anxiety. Normally I have trouble just sitting in a group without opening my mouth the anxiety is so bad. I didn't analyse what I had said or how badly I had done it. For once it didn't seem to matter. It felt like I was on valium without the sedation.

As I came off the Rebox I experienced a nervous rebound. The anxiety got worse and worse over a day and a half -incl social anxiety.

So I started the Rebox again but reduced the dosage to .5mg (don't laugh). On this dose I experienced increased energy, no negativity and slightly increased heart rate. The best part was the ability to sit still and focus while I read.

Over the last week I feel like my brain is clearer and sharper and I'm remembering what I'm studying. I also took 40 sec off my best running time for an 8k run I do.

I wouldn't say that it is improving my social anxiety specifically yet but I have had no panic and this is a huge barrier to socialising etc to me. I have had a couple of times where the eye contact stuff got hard but not consistently.

At this dose I feel a little jittery but it is different. Sometimes I think it is my brain interpreting the increased heart rate as nervousness. I carry Propranolol at work and used it twice.

A couple of times I have felt really tired and started to feel brain dead again but by taking tyrosine it seems to reverse this. In fact I ended up increasing the jitteriness doing this but it wore off.

I'm sleeping ok although I have had 2 or 3 early wakenings but it didn't bother me.

I suppose noradrenaline suits me. I'm curious to see whether the 'nervousness' wears off.
I can't help thinking that so many people might be missing out on the positive effects of drugs because of the wrong dosage (for them) and not having information about using supplements too. I suspect paradoxical effects of drugs may just be getting the dosage wrong for the individual.

Have you tried reducing the Wellbutrin dosage, MM and then increasing it as you feel able?

sabre

 

Re: Does Norepinephrine cause anxiety?

Posted by Spriggy on March 5, 2005, at 13:03:43

In reply to Re: Does Norepinephrine cause anxiety?, posted by sabre on March 5, 2005, at 12:53:41

I know I had a hard time with anxiety (but it was a "different" anxiety) on wellbutrin but I also have anxiety on any SSRi's as well.

The anxiety felt different in nature.

With the Wellbutrin, I could not sleep-- I mean I literally went 4 days with NO sleep. I felt like I couldn't sit still. I would pace the floor. I almost became agraphobic I was so anxious and panicky.

But with the SSRI's, I felt a more internal resltness and very uncomfortable in my own skin feeling. It was almost a more anxiety of the mind than the body(which wellbutrin produced).

With the SSRI's, I wanted OUT of my own skin, which is why I think I became suicidal. I could not feel comfortable in my own body/mind.

I felt more insane on SSRI's than I did on Wellbutrin. Wellbutrin felt like speed to me.

 

Re: Does Norepinephrine cause anxiety? » sabre

Posted by ed_uk on March 5, 2005, at 13:07:10

In reply to Re: Does Norepinephrine cause anxiety?, posted by sabre on March 5, 2005, at 12:53:41

Hi sabre!

It's good to hear you're doing well :-)

>A couple of times I have felt really tired and started to feel brain dead again

Do you think this was when your dose wore off?

>So I started the Rebox again but reduced the dosage to .5mg

Is this the dose you're currently taking? Perhaps it would help to take it three times a day instead of twice daily.

Ed.

 

Re: Does Norepinephrine cause anxiety?

Posted by MM on March 5, 2005, at 17:58:16

In reply to Re: Does Norepinephrine cause anxiety? » sabre, posted by ed_uk on March 5, 2005, at 13:07:10

I'm just going to try to reply to everyone in one post and then answer specific questions....I have tried all the SSRI's (I think), Serzone, Effexor, Wellbutrin, and the only other NE effecting drug I took that I know of was Strattera. I didn't sleep for 3 days on Strattera. I tried, laid in bed, just couldn't sleep. I took Effexor a while ago, so I can't remember what it did exactly, but I'm pretty sure I didn't hate it. I haven't tried any TCA's yet. I'm trying to get a better understanding of meds before I try more of them so that I can try ones that I think would work the best first. I've recently learned that Pdoc's don't often follow the science of the meds they prescribe, and this makes sense to me....
Reboxetine seemed like an interesting drug...it's part of the reason I ask about norepinephrine. Serzone also increased my anxiety, this vigilance thing, and I think Serzone is an SNRI? I don't understand this stuff very well, obviously, and I'm not trying to be a neuropharmacologist or whatever...I'm just trying to help myself the best I can. I'm the only one trying to figure out the mystery of my brain. I would love it if I could just sit back and the doctor would heal me but that hasn't happened and I won't give up yet. My goal with this post was to move a little closer to isolating what I need to tweak in my brain...Since Wellbutrin works great for my depression, I don't want to lose whatever that is, but....
My most helpful drug has been Klonopin I believe...Trileptal has helped some too, in that it helps me be more stable and kinda numb.
Thanks for the replies.
MM

 

Re: Does Norepinephrine cause anxiety? » sabre

Posted by MM on March 5, 2005, at 18:07:26

In reply to Re: Does Norepinephrine cause anxiety?, posted by sabre on March 5, 2005, at 12:53:41

The 150mg pills of Wellbutrin are the kind you can't cut, and I don't have any of the 75mg's left so I haven't been able to reduce it yet. I will probably after I see my pdoc. I've tried wellbutrin with an SSRI too, but I've come to the conclusion that I just can't be on SSRI's. Not sure what supplements I would want to take to augment the Wellbutrin (cuz I dunno what it even does lol).

I had read many places that Norepinephrine was good for anxiety, so when I read somewhere that it could cause it I had to ask about it. Dunno if I got an answer exactly, at least not a simple one. I guess it just depends.

Do you live in America? (I doubt it since you're on Reboxetine, but I guess some people can get their docs to order it)

Thanks sabre.
MM

 

Re: Does Norepinephrine cause anxiety? » Ritch

Posted by MM on March 5, 2005, at 18:10:55

In reply to Re: Does Norepinephrine cause anxiety? » MM, posted by Ritch on March 5, 2005, at 9:34:21

I think Wellbutrin does help with some of my anxiety, but then adds more of a different kind? I have yet to try TCA's or Cymbalta (I don't even know what that is, so I'll have to research it). I did take effexor long ago, without a mood stabilizer, and I'm not sure what my exact reaction to it was, but I don't think it was too bad, so maybe I need to try that one again. Sorry if you already answered this, but did you find the SSRI's helpful?
Thanks Ritch/Mitch.
MM

 

Re: Does Norepinephrine cause anxiety? » Spriggy

Posted by MM on March 5, 2005, at 18:16:27

In reply to Re: Does Norepinephrine cause anxiety?, posted by Spriggy on March 5, 2005, at 13:03:43

I felt the way you did on Wellbutrin when I took Strattera...Couldn't sleep, felt like speed to me. I also had bad reactions to the SSRI's too. I had agitation and apathy which was a bad mix, plus I felt totally insane, like I was tripping. Seems like the majority of people here didn't react so well to SSRI's? I could be wrong about that; just my observation.
Thanks Spriggy.
MM

 

Re: Does Norepinephrine cause anxiety?MM

Posted by sabre on March 5, 2005, at 18:36:32

In reply to Re: Does Norepinephrine cause anxiety? » sabre, posted by MM on March 5, 2005, at 18:07:26

Hi MM
I also hated SSRIs. Increased my anxiety.

I tried Serzone for approx 6 mths and found it better than the SSRIs. It reduced the social anxiety a little but made me feel numb and dumb. I think it works on both NA and serotonin but isn't a very strong anti depressant. After it was removed from the market I went off it slowly and the old symptoms gradually returned.

After experimenting with tyrosine I found my energy levels improved and panic reduced but not always consistently.

I live in Australia and Reboxetine is available here. Isn't Strattera a NARI? I thought I read that in Crazy Meds. Could you try a v low dose and increase it slowly, using your sleep patterns as a guide, i.e. don't increase it if you can't sleep. Maybe give the tyrosine a go too?
sabre


 

Re: Does Norepinephrine cause anxiety? Ed

Posted by sabre on March 5, 2005, at 18:55:55

In reply to Re: Does Norepinephrine cause anxiety? » sabre, posted by ed_uk on March 5, 2005, at 13:07:10

Hi Ed
Thanks!

I have just finished my first week and was wondering about upping to a third daily dosage or just increasing the two doses I'm on now.
I think the third dose does sound a better option. I'll try 3x .5mg.

I didn't mention it but I also found in the first 1/2 of the week that I tipped between a bleak passing depressed state esp upon waking. I think this coincided with the morning drop in NA levels. I also found it returned in the afternoon. At other times my mood swang into overdrive and I felt invincible and overly ambitious- usually around 4hrs of taking the reboxetine.

I have overdone my efforts during my running training this week and I am in a bit of a physical hole today. I think I need to resist the temptation of using the drug as a physical upper as I am sure the body pays for it later!

Over the last couple of days I think my mood hasn't been swinging as much and perhaps this indicates that a dose increase is ok at this stage. Another sign for me was the gradual return of IBS symptoms. I think Reboxetine at the right dose would be v useful for those suffering from this complaint.

From what I have read, Reboxetine is good when your adrenals are a bit burnt out. I am guilty of pushing too hard in general and the panic and SA make me ooze adrenalin. Inbetween the social stresses I have been flat, tired and unable to concentrate.

My only concern is that what happens when you lift the NA by pouring tyrosine and Reboxetine into the system. Is it like taking an upper and will my brain and body flag and cave-in in the future?
Meanwhile...the experiment continues.
sabre

 

Re: Does Norepinephrine cause anxiety?

Posted by Dinah on March 5, 2005, at 21:17:44

In reply to Re: Does Norepinephrine cause anxiety? » Dinah, posted by SLS on March 5, 2005, at 9:30:23

> Hi Dinah.
>
> > Does that mean I ought not to be so quick to rule out anything that acts on NE? I did very very badly on Effexor/Wellbutrin/Nortriptyline.
>
> Were your reactions to these 3 drugs exactly the same? If not, what were the differences? How long did you take each of these drugs?

No, Wellbutrin was the worst. Probably because I was on it longest. It actually did help some so I kept trying to stick it out. But it nearly killed me. Literally.

Effexor and Nortriptyline had nearly the exact same effect as each other. Very shortly after starting them (too soon to officially work) I had a couple of days of feeling GREAT, too good really. Then I stopped sleeping for the most part, then I got that horrible electricity running through my skin feeling. I think I stuck out Effexor for a month, maybe less, and I quit Nortriptyline much quicker because it felt so similar. In the case of Effexor, I basically lost a couple of months of work and life.
>
> > So much so that I've come to view NE as poison for *me*.
>
> It indeed might be, but given the cost to you of not exploring new drugs, it probably make sense for us to act less like brilliant neuropsychopharmacologists and more like patients, although playing the part of the former is much more fun. Experimentation is a necessary evil here.
>
> > But are you saying there could be NE affecting drugs that don't send me to jittery, itchy-crawly, akasthesia h*ll?
>
> Yes.

Oh lordy. It'll be hard for me to get over my NE phobia, if I try another. And it would have to be at a time of low workload, because I can't afford to lose a month of work. And I'm terrified of the idea.

>
> How does amphetamine (Dexedrine or Adderall) affect you?

Never took it. Provigil made me feel speedy at first, not the same feeling as the Effexor, Nortriptyline, or Wellbutrin. Just a racy sort of feeling. But that wore off and now it barely works at all. I'm taking half what was prescribed and may go up to the amount prescribed, but I worry when I have to increase the amount of a drug to get the same effect. I'm a medication Puritan, I think.
>
> > Might Cymbalta or another tricyclic be ok?
>
> Arghhh! I don't know. :-( I wish I did. Sorry.
>
> I am disappointed to hear that nortriptyline gave you so much trouble. I would say that anxiety can be a passing side effect and generally resolves within a week or two. Toss Wellbutrin out for the moment. Effexor and nortriptyline both exert pro-serotonergic effects. Desipramine does not. It might be interesting to see how taking a drug that doesn't mix NE and 5-HT reuptake inhibition would affect you.
>
> Do you avoid entirely those drugs that have the potential to produce weight gain?
>
No, I'm already fat as a cow. And I'm on depakote. I don't think I'll gain any more, but I doubt I'll lose anything either.

> Which SSRI did you find to be the most helpful?
>
Luvox was the only one I took.

> Whichever one it is, add Remeron and lithium to it and play with Lamictal if necessary.
>
> No way, huh?

Sigh. Remeron put me to sleep for 36 hours with an additional 24 or so hours of intense grogginess. My doctor said that increasing the dose would help so he did, and it helped. I slept for 24 hours straight with another 24 of grogginess. :) It's in the cabinet of failed medication experiments.
>
> :-)
>
>
> - Scott
>

Thanks Scott. I think half the problem is that I can't afford to take a long term view. Losing a couple of weeks of work would be disastrous at this point. Doing half-*ssed work is preferable right now, as long as they see me working.

Sigh.

 

Above for Scott (nm)

Posted by Dinah on March 5, 2005, at 21:18:32

In reply to Re: Does Norepinephrine cause anxiety?, posted by Dinah on March 5, 2005, at 21:17:44

 

Re: Does Norepinephrine cause anxiety? » MM

Posted by Ritch on March 5, 2005, at 22:06:56

In reply to Re: Does Norepinephrine cause anxiety? » Ritch, posted by MM on March 5, 2005, at 18:10:55

> I think Wellbutrin does help with some of my anxiety, but then adds more of a different kind? I have yet to try TCA's or Cymbalta (I don't even know what that is, so I'll have to research it). I did take effexor long ago, without a mood stabilizer, and I'm not sure what my exact reaction to it was, but I don't think it was too bad, so maybe I need to try that one again. Sorry if you already answered this, but did you find the SSRI's helpful?
> Thanks Ritch/Mitch.
> MM

I also noticed a *reduction* of anxiety AT FIRST, when I start up WB. But afer a few weeks it worsens and gets worse than it was in the beginning. That's why I think the parent drug is what does the good for me, and the metabolites cause most of the trouble (accumulating with time). SSRI's have always been "helpful" with anxiety, but with dose levels above microcosmic I get mixed episodes and increased bipolar cycling.

 

Re: Does Norepinephrine cause anxiety? » Dinah

Posted by SLS on March 6, 2005, at 5:26:39

In reply to Re: Does Norepinephrine cause anxiety?, posted by Dinah on March 5, 2005, at 21:17:44

Hi Dinah.

If I were you, I would be just as reluctant to start anything new when I could least afford to experience drug reactions that are impairing. I waited 6 months or so before beginning treatment because of my impending wedding and moving into a new house. It just so happens that the very next drug combination worked. It was the only one that ever did. Unfortunately, it no longer does.

If, when you are ready, you would like some additional input, you know where to find me. In the meantime, I am sending you warm thoughts of prayer and strength that this time passes as easily as possible for you.


- Scott

 

Re: Does Norepinephrine cause anxiety? » SLS

Posted by Dinah on March 6, 2005, at 8:52:34

In reply to Re: Does Norepinephrine cause anxiety? » Dinah, posted by SLS on March 6, 2005, at 5:26:39

You're terrific, Scott. Thank you.


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