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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by chess on December 25, 2004, at 12:00:37
Anyone have success using Gabitril for anxiety?
Posted by Phillipa on December 25, 2004, at 21:15:49
In reply to Gabitril success stories for anxiety?, posted by chess on December 25, 2004, at 12:00:37
I'lm not familiar with this med. What is it? Is it a mood-stabalizer? Phillipa
Posted by jeopardy on December 26, 2004, at 10:01:34
In reply to Re: Gabitril success stories for anxiety?, posted by Phillipa on December 25, 2004, at 21:15:49
I was Rx'd Gabitril 4mg,bid. I'm not quite sure of the results I'm suppose to receive. Does it take time to build up like a SSRI ect...since this is suppose to slow the re-uptake of Gaba. Any feedback and or experiences would be appreciated...ie. mg/dosage when you take it, how long you've been taking it, pros & cons, ect. Thanks, Jeopardy
Posted by ed_uk on December 28, 2004, at 10:39:24
In reply to Re: Experience w/GABITRIL...any longtime users?, posted by jeopardy on December 26, 2004, at 10:01:34
Low-dose tiagabine effectiveness in anxiety disorders.
Schaller JL, Thomas J, Rawlings D.
Professional Medical Services of Naples, Naples, Florida, USA.
BACKGROUND: Gamma-aminobutyric acid (GABA), the predominant inhibitory neurotransmitter of the central nervous system, is involved in the pathophysiology of a wide variety of disorders, including anxiety. Tiagabine hydrochloride acts as a selective GABA reuptake inhibitor (SGRI). METHODS AND RESULTS: Consecutive patients were offered tiagabine in 1-mg incremental doses for the treatment of anxiety, primarily generalized anxiety disorder. Individuals failing anxiety treatment with benzodiazepines, selective serotonin reuptake inhibitors, and buspirone, and/or with a strong family or personal history of substance abuse were allowed trials. The SGRI tiagabine improved anxiety and was well tolerated by adult patients with generalized anxiety disorder as well as one patient with anxiety secondary to acute antidepressant withdrawal. One disinhibition treatment failure is also discussed. CONCLUSION: In acute anxiety treatment, very low initial dosing with gradual increases may be sufficient for anxiety effects, when compared with the higher doses of tiagabine used in epilepsy treatment. Tiagabine may be useful in the treatment of generalized anxiety disorder.
This is the end of the thread.
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