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Dr. Bob is Robert Hsiung, MD,
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Posted by dancingstar on December 21, 2004, at 1:02:53
In reply to Re: Side Effect- Liver Damage (Effexor Cymbalta) » absolute, posted by S. Bartel on December 18, 2004, at 22:17:42
Sammi's right; according to the Physician's Desk Reference, Effexor can cause liver damage.
Posted by Cindy S. G. on December 21, 2004, at 8:37:57
In reply to Re: Anyone had success on Effexor XR? , posted by Cindy W on January 11, 2000, at 22:18:51
I started on Effexor XR about six months ago. My doctor started me on the 37.5 for two weeks and then on 75 mg. I took that for a while. I had so much energy the first week. Before the effexor I was very depressed and had a lot of anxiety. I was closing myself off to just about everyone. I could not sleep at night and had trouble waking in the morning and was in danger of losing my job for being late. Once I started taking the medication I saw very rapid improvements. I also take Prevacid 30 mg. so I wasn't nauseated. I could sleep better and I woke when the alarm clock went off. I felt like moving and it is definitely an appetite suppressant. I hardly eat anything at all. I do have increased elevations of cholesterol since taking the medication. I also experience confusion at times. My doctor increased my medication to 150 mg (effexor xr). This worked for about a week and a half. My family and friends have noticed that I seem more myself since taking the meds. I did not tell them I was on it. What I do not like about the meds is that I will be in the middle of a sentence and forget totally what I was about to say. It causes a lot of confusion and is hard for me to concentrate on things for a long period of time. I have been on the 150mg for about a month now and I seem to be going back to my restless self of not sleeping at night and being hard to wake up in the morning. I still feel a little depressed, but not like I used to. I do not know if I need to have my doseage increased or not. Let me know if anyone else is experiencing this same thing.
Posted by dancingstar on December 21, 2004, at 12:15:58
In reply to Re: Anyone had success on Effexor XR?, posted by Cindy S. G. on December 21, 2004, at 8:37:57
Though you should be able to trust the judgment of your doctor, it would be in your best interest to read everything that you can about Effexor before increasing your doseage. ( www.wyeth.com )
Your experience is tracking along the same time lines as those of us that found out too late that we lost years of our lives because of taking E. Just be sure that if you take it, you are doing so with full knowledge and consent that it can cause various problems that you are currently having, including fatigue and depression. I have come to understand that our doctors may not know this. They also do not seem to be right on top of the fact that there is no way to be sure that we can get this drug out of our system, though some people have an easier time of it than others.
Posted by Markku on December 21, 2004, at 18:18:38
In reply to Re: Effexor: I love you, but all good things must end » als1972sd, posted by dancingstar on December 17, 2004, at 14:02:31
> I wonder what happens if you stop taking Lexapro and don't take anything at all? Will you take these drugs for the rest of your life?
>
> With regard to "reported side effects," meaning no disrespect, I have come to understand that no one tells the truth about these sorts of things.
>I have taken both Effexor and Lexapro for panic. I had bad withdrawal effects from Effexor, but not so much from Lexapro. I was able to reduce my dose of Lexapro and started taking it only when I felt I needed it, even though my doctor probably wouldn't be happy with me doing such a thing. I now only take 5 mg when I feel symptoms or have trouble sleeping. With Effexor that didn't seem like an option because it felt like the shock sensations would never go away (unless I took another dose). It actually took a couple months for all traces of those sensations to finally go away after I stopped taking Effexor.
Posted by absolute on December 22, 2004, at 0:41:17
In reply to Re: Side Effect- Liver Damage (Effexor Cymbalta), posted by dancingstar on December 20, 2004, at 0:12:21
Has anyone had these side-effects?
I've noticed at work, after a few hours my thoughts get cloudy and I can't concentrate very well. I don't think this is related to hunger, lack of sleep, or any need for caffeine. It's really hard to differentiate between a normal response to stress and a side-effect of medication .
The skin rash is strange-- I have one under my eye that has not gone away in a few weeks. Never had anything like that before. Any long-term users of Effexor noticed anything like this??
Posted by beppe on December 22, 2004, at 3:25:22
In reply to Re: Effexor: I love you, but all good things must end » als1972sd, posted by dancingstar on December 17, 2004, at 14:02:31
hello this is my first time poasting. i'm very upset right now. i am 22 and have been on effexor xr for about 6 years now. i feel like i am a slave to it. i have a love hate relationship w/ it. i hate how i feel if i don't take it i'm physically and emotionally very sick. i get this wierd feeling when i turn my head in my chest and i'm so dizzy. i can't stop crying and i can't cry at all when i take it. my family will not support me in trying to ween myself off, they say i need it. i don't know what to do. i have been sleeping 13-20 hours a day and i think about suicide often. can anyone relate? please help me
Posted by dancingstar on December 22, 2004, at 10:48:06
In reply to effexor xr withdraw » dancingstar, posted by beppe on December 22, 2004, at 3:25:22
You've been taking Effexor since you are 16 years old? Wow, it would be wrong of anyone -- even me, who doesn't like this drug much at all -- to tell you to stop taking it. You need really good medical care, and you need to tell the doctor how you feel and why you feel this way. Now that I've done it, I can never tell anyone to just stop taking E, it was the hardest thing that I have ever done. If you want to stop, you really need someone to help you. Work calmly and rationally to get your doctor's support. Maybe you can tell him that an antidepressant is supposed to make you less depressed, not to leave you feeling suicidal.
The truth is that you probably know your own body better than the people that are not taking the drug, but they love you very much and are afraid for you cause they want you to be well. You, like me, may have to do some research in order to show them facts where other people have had similar problems with Effexor after being on it for a lengthy period of time. Don't give up...don't give in, and for goodness' sake, please don't take this out on yourself, please promise me!!!!!!! Also, promise me that you will have help getting off of Effexor if that is what you ultimately decide to do because you must not do this alone if you are in a fragile state. It is very difficult for some of us. Be patient with yourself and with everyone that loves you. Things will come together, and you will begin to feel better again, though it might not happen as quickly as you would like.
Blessings.
Posted by KarenQ on December 22, 2004, at 20:21:12
In reply to Withdrawl symptom?, posted by kmp68 on December 2, 2004, at 14:00:54
I am weaning off of Effexor right now and am late. When I first went on it, I was about 10 days late with my first cycle and was worried that I might be pregnant at the time. Thank God I wasn't. So, evidently Effexor has some sort of effect on the hormones. I'll be glad when its out of my system all together.
Posted by S. Bartel on December 23, 2004, at 8:12:21
In reply to Side Effects- Lethargic, Skin Rash?, posted by absolute on December 22, 2004, at 0:41:17
> Has anyone had these side-effects?
>
> I've noticed at work, after a few hours my thoughts get cloudy and I can't concentrate very well. I don't think this is related to hunger, lack of sleep, or any need for caffeine. It's really hard to differentiate between a normal response to stress and a side-effect of medication .> The skin rash is strange-- I have one under my eye that has not gone away in a few weeks. Never had anything like that before. Any long-term users of Effexor noticed anything like this??
Yes I broke on my arms and face. Only a little at first and then a lot. I looked like I had chicken pox scabs all over my face. Thought it was an allergy for a long time and tried everything to cure it.
Feeling lethargic and having trouble concentrating is a common side effect. It only gets worse. After being off Effexor XR for about 9 weeks, I still have trouble concentrating and can't do more than one thing at a time without becoming very confused and anxious. At least the breaking out has finally gone away. It was so embarrassing.
Posted by Cindy S. G. on December 23, 2004, at 8:25:33
In reply to Re: Side Effects- Lethargic, Skin Rash? » absolute, posted by S. Bartel on December 23, 2004, at 8:12:21
I have had a very bad break out on my face since my doctor increased my medication from 75 mg to 150 mg. I look like I am peeling off my top layer of skin. It looks horrendous. I have tried everything to no avail. I have also gotten over the newness of the increase and am back to having trouble waking up in the morning. I was 45 minutes late to work this morning. I feel very depressed and have not had any energy at all. I had a few days off for the pre holiday week and I didn't do anything at all but lay around the house the whole time and worried about everything that needed to be done, but I didn't do. I can't take too much more of this.
> > Has anyone had these side-effects?
> >
> > I've noticed at work, after a few hours my thoughts get cloudy and I can't concentrate very well. I don't think this is related to hunger, lack of sleep, or any need for caffeine. It's really hard to differentiate between a normal response to stress and a side-effect of medication .
>
> > The skin rash is strange-- I have one under my eye that has not gone away in a few weeks. Never had anything like that before. Any long-term users of Effexor noticed anything like this??
>
>
> Yes I broke on my arms and face. Only a little at first and then a lot. I looked like I had chicken pox scabs all over my face. Thought it was an allergy for a long time and tried everything to cure it.
> Feeling lethargic and having trouble concentrating is a common side effect. It only gets worse. After being off Effexor XR for about 9 weeks, I still have trouble concentrating and can't do more than one thing at a time without becoming very confused and anxious. At least the breaking out has finally gone away. It was so embarrassing.
>
Posted by S. Bartel on December 23, 2004, at 8:46:59
In reply to Re: Side Effects- Lethargic, Skin Rash? » S. Bartel, posted by Cindy S. G. on December 23, 2004, at 8:25:33
I'm no M.D., but it sounds like this is not a drug for you and personally I think it should be taken off the market. Stopping the drug is not easy, but it can be done. All I did was lay around and sleep. I had no energy or desire to do anything. I just wanted to stay home and be alone and do nothing. The side effects can be horrendous. I have a long list of them including irresible liver desease, dangerously high cholesterol and tryglicerides. I feel so much better since coming off effexor and I was on it for 7 years. The whole time being in a fog and not realizing what was causing it. Good luck.
Posted by Gia on December 23, 2004, at 8:51:55
In reply to Re: Side Effects- Lethargic, Skin Rash? » Cindy S. G., posted by S. Bartel on December 23, 2004, at 8:46:59
I have the same side effect I thought that maybe thats what being happy was staying home and just being happy enough though I never want to do anything I seem really lazy and just want to sleep as much as I can. I also have a rash on the side of my nose and on my chin, its red and it gets dry and peels, is this one of the side effects I wonder???
Posted by dancingstar on December 23, 2004, at 12:34:52
In reply to Re: Side Effects- Lethargic, Skin Rash?, posted by Gia on December 23, 2004, at 8:51:55
...let's take the other side for a minute in fairness to the people that have been yelling at me, like my best friend who says that I am being irresponsible in wanting this drug off the market. Staying at home being happy is better than wanting to kill yourself or running all over town being miserable. But, that said,...only each of us knows how far this can go before you have to wonder if this, too, is the wrong answer.
There is an article in this month's O Magazine about jogging and other exercise, about approaching it very slowly so as not to overload your body and burnout, but the article does explain metabolic changes that it makes in the brain in order to bring about physical changes in people with depression and anxiety. It also makes the point that this is the most difficult thing to get people to do. This is not in any way to say that anyone should stop taking drugs, just that the article is a worthwhile read.
Posted by dancingstar on December 23, 2004, at 14:13:43
In reply to Re: Side Effects- Lethargic, Skin Rash? » S. Bartel, posted by Cindy S. G. on December 23, 2004, at 8:25:33
Hi Cindy,
I never had any skin problems from Effexor until after I stopped taking it, but we all react differently to chemicals.
I could not wake up while I was taking it, especially while on 150 mg., probably even if there were a fire in the house. I slept through jury duty ;-). Nothing could keep me awake.
Posted by not2late4u on December 24, 2004, at 3:50:56
In reply to Re: Side Effects- Lethargic, Skin Rash? » Cindy S. G., posted by dancingstar on December 23, 2004, at 14:13:43
PROS and CONS
Hello, first time posting. I just spent 45 minutes reading over some past posts. Wow. I have been taking Effexor xr for about 2 yrs. Recently increased to 225mg. I was on Paxil, but gained weight and it really didnt address depression, just anxiety for me. Nice to know that the "electric" feeling in back of head and cant seem to get out of bed in the morning, is not just me. Other things, lack of sex drive, some increased headaches with exercise (anyone else experience this?) I do want to get off, eventually, hopefully sooner than later. I have to wonder how many of you and others are actually being MONITORED by a PSYCHIATRIST who is much more knowledgable about these types of medications. I see my psychiatrist about every 2 months just to check in and see how its going. It takes about 10 minutes. Why would anyone ever just stop taking the medication? Doesnt the pharmacy give information about not stopping the drug without consulting your doctor? I had a hard time with Paxil, whooo, it was HELL when I just missed a day. When I transferred over to Effexor I was wheened off at the same time I was starting Effexor and it was seemless. I dont know what to expect when I SLOWLY withdraw from Effexor, but I am not sorry I took it, it got me where I am today, much more functional and in a place where I can work on things so I can get off it. Just hope its not chemical imbalances that will keep me from getting off and I am afraid to go off not because of side effects, I think dont think much can top the 24/7 anxiety I had for several months straight, its the fear of experiencing that constant anxiety again. Well I've got an appt with a counselor to help me sort this through along with some PSTD. I will get will be free from medications some day! I've decided to put my trust in my Lord God and go from there. REMEMBER, you CANT just stop taking ANY anti-depressants!!!! You really need to have a psychiatrist help you along. Not a family doctor. Sorry, just my point of view. I pray all of us are able to overcome our hardships.
Posted by jubilee on December 24, 2004, at 8:56:32
In reply to Re: Side Effects- Lethargic, Skin Rash?, posted by not2late4u on December 24, 2004, at 3:50:56
I have tried ove and ove to read the posts , but effexor has totally meesed with my ability to read and consentrate, so I might not be following any particuar subject. I get 2 or 3 pages read in a book daily and I was an avid reader. Been off effexoe , after going slow 5 months for about a week now ( one small dose 4 days ago. My mind is in a fog and I get real emotional, and I definatly have had a personality change , but then I am going through some other heavy stuff also. Most my issues , like effexor blackouts I stull suffer with , still have severe memory lloss , which is a side affect of effexor, anxiety, emotional, nervous( and why they would give effexor for anxioty when thats one of its ver yside astounds me as I have been "hypermanic since I was put on it 4 tears ago, Fekt like I was going to jum out of my skin , when they called it Bi Polar. Got to close and a happy holiday to you all , Jubilee
Posted by dancingstar on December 24, 2004, at 11:13:16
In reply to Re: Side Effects- Lethargic, Skin Rash?, posted by Gia on December 23, 2004, at 8:51:55
Gia,
If you want to be happy on Effexor, you shouldn't be reading this board. There are many of us who will tell you the negative effects of a drug that is one of the most prescribed drugs on the market...until I do my best to have that changed because I believe that the horrendous side effects have been largely under-reported.
Posted by dancingstar on December 24, 2004, at 11:14:52
In reply to Re: Side Effects- Lethargic, Skin Rash?, posted by dancingstar on December 24, 2004, at 11:13:16
I didn't mean that to be as harsh as it sounded. I only said it cause I know that you recently started taking Effexor and wanted to give it a fair try.
Posted by KaraS on December 24, 2004, at 13:45:25
In reply to Re: Side Effects- Lethargic, Skin Rash?, posted by dancingstar on December 24, 2004, at 11:14:52
I just wanted to add another perspective here. Effexor helped me more than any other antidepressant to date (and that includes MANY years of trials). I also tolerated it unusually well. I couldn't even tell I was taking anything except for the muted sexual desire and anorgasmia. Unfortunately, despite being better than anything else I've taken to date, Effexor still only gave me limited help. (I used to think that maybe I had 20% mood lift from it but now that I'm off of it I realize that the number is probably more like 40-50%.) I recently went off of it to search for a more comprehensive solution - one that would help provide some energy and motivation.
My experience going off of Effexor wasn't all that bad either thanks to the advice I received on this board. I decreased my dosage very slowly and then substituted a longer acting SSRI at the very end. Without that strategy it probably would have been a nightmare. I think it's criminal that most pdocs don't know enough to utilize this method of withdrawal with their patients. I don't know if this method would end the withdrawal problems completely but it sure can't hurt (and in my case it DID take care of the problem completely).
I would not hesitate to go back on Effexor and try to augment it with other medications in the future. I am not trying to discredit other people's experiences here. I'm just giving you my experience. YMMV.
Kara
Posted by dancingstar on December 24, 2004, at 14:42:11
In reply to Re: my Effexor experience, posted by KaraS on December 24, 2004, at 13:45:25
Hi Kara,
Actually, I wish that we had a more diverse population from which to draw our conclusions. I think that what happens is that when we are having a dramatic reaction to withdrawal with or without a tapered withdrawal and with or without the addition of Prozac as is indicated in one of the links that I posted (but was previously posted by someone before me - to whom I am very grateful) we do an internet search and end up here.
Admittedly, this is not an unbiased group, yet the fact so many people are predisposed to experiencing a negative reaction leads me to believe that the reported rate of 2 percent is underestimated by Wyeth and the fact that Effexor is prescribed by so many general as opposed to P doctors should perhaps be something that needs to be seriously reviewed. As it stands, there is no cure for those of us with serious reactions to Effexor. That alone is to me unacceptable, and there is no way to tell whether or not any of us will be one of those people as far as I can tell.
As far as modifying the level of depression that you have, I am not in the least being condescending when I ask whether you have added exercise into your daily regimen, only because it has in many cases proven to be as effective as drugs.
In any event, thanks for your perspective, and I hope you are feeling better soon.
Bebe
Posted by not2late4u on December 24, 2004, at 14:44:35
In reply to Re: Side Effects- finally off effexor, posted by jubilee on December 24, 2004, at 8:56:32
Hi Jubilee, if you are bi-polar, not sure effexor is/was the best for you. Im not an expert but I have family members who have it and they've told me that effexor isnt one they normally use for bi-polar. Hope you find whats works for you.
Posted by not2late4u on December 24, 2004, at 14:53:19
In reply to Re: my Effexor experience, posted by KaraS on December 24, 2004, at 13:45:25
I am new to this site, got here because I did a search and saw, is effexor working for you? I didnt realize I was on a site that "hated" effexor and that my experience wouldnt be welcome. I actually learned some things from this site, why I cant sleep until 3-4am and dont want to get up until after noon and have to force myself to get up. Thats been a HUGE issue for me and thought it was a bad habit or still had depression or whatever. Anyways, I do think there are pros and cons to medication in general. Everyones pros and cons are different with each medication. I think the FDA can do a better job with ALL meds, not just effexor. I do plan on talking to my psych and weening myself off after the first of the new year. I want to see if I've made enough changes to be free of anxiety/depression without meds. God Bless. Renee
Posted by dancingstar on December 24, 2004, at 15:14:34
In reply to Re: Side Effects- Lethargic, Skin Rash?, posted by not2late4u on December 24, 2004, at 3:50:56
You're lucky that you know that you can't just stop taking antidepressants.
Yesterday I had an appointment with my internist. When I mentioned that Effexor is being prescribed for the symptoms of menopause, he acknowledged that I was right; that it is one of the four top prescribed drugs in the country. Considering this, it is my opinion that there should be no misinformation, no lack of clarity, no question whatsoever in the minds of the public about what they are taking as most of the public is not seeing a pschiatrist and is not informed about all of the side effects of Effexor. Because it is so widely prescribed, that makes it particularly unacceptable that so many of us know so little about what can happen to us if we take E, at least to me.
Posted by KaraS on December 24, 2004, at 15:16:17
In reply to Re: my Effexor experience, posted by dancingstar on December 24, 2004, at 14:42:11
> Hi Kara,
>
> Actually, I wish that we had a more diverse population from which to draw our conclusions. I think that what happens is that when we are having a dramatic reaction to withdrawal with or without a tapered withdrawal and with or without the addition of Prozac as is indicated in one of the links that I posted (but was previously posted by someone before me - to whom I am very grateful) we do an internet search and end up here.
>
> Admittedly, this is not an unbiased group, yet the fact so many people are predisposed to experiencing a negative reaction leads me to believe that the reported rate of 2 percent is underestimated by Wyeth and the fact that Effexor is prescribed by so many general as opposed to P doctors should perhaps be something that needs to be seriously reviewed. As it stands, there is no cure for those of us with serious reactions to Effexor. That alone is to me unacceptable, and there is no way to tell whether or not any of us will be one of those people as far as I can tell.
>
> As far as modifying the level of depression that you have, I am not in the least being condescending when I ask whether you have added exercise into your daily regimen, only because it has in many cases proven to be as effective as drugs.
>
> In any event, thanks for your perspective, and I hope you are feeling better soon.
>
> BebeBebe,
That's all true and, again, I am not downplaying the negative experiences that others have had. I agree that there is no way to tell who will have a really bad experience on it. OTOH, can't the same be said about all other psychotropic medications? They're all somewhat risky. I think that with all of them we have to do a personal cost/benefit analysis. Perhaps Effexor is more risky than many others. I don't know. If I were one of the people who had a horrible reaction, then I'm sure I'd feel the same way you do about it.
I have tried exercise and natural supplements. Exercise has helped me some in the past but it did not take care of the whole problem - not by a longshot. I think it should be a part of everyone's daily routine for many health reasons but it's not enough of an antidepressant for me to allow me to function well in the world.
I prefer and continue to try natural supplements. I'm a regular on the Alternative Board. I'm definitely not biased against nonmedication methods. (I'm currently using niacinamide (Vit. B3) for anxiety control. It works like a natural benzo.) But, I'm also serously depressed and feel that I need more at this time. If that means medication, then I'll take it and assume some risk.
Take care,
Kara
Posted by KaraS on December 24, 2004, at 15:22:40
In reply to Re: my Effexor experience, posted by not2late4u on December 24, 2004, at 14:53:19
> I am new to this site, got here because I did a search and saw, is effexor working for you? I didnt realize I was on a site that "hated" effexor and that my experience wouldnt be welcome. I actually learned some things from this site, why I cant sleep until 3-4am and dont want to get up until after noon and have to force myself to get up. Thats been a HUGE issue for me and thought it was a bad habit or still had depression or whatever. Anyways, I do think there are pros and cons to medication in general. Everyones pros and cons are different with each medication. I think the FDA can do a better job with ALL meds, not just effexor. I do plan on talking to my psych and weening myself off after the first of the new year. I want to see if I've made enough changes to be free of anxiety/depression without meds. God Bless. Renee
Renee,
I don't think it's fair to say that this whole site hates Effexor - though there is a considerable amount of anger towards it among a large vocal group. There are also members here who are on it now or have been on it in the past and have had better experiences on it (including myself). At any rate, I hope that you are successful in going of it and operating without medication.Good luck and definitely follow the advice you find on here about how to withdraw from it!
Kara
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