Shown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by Wildman on November 12, 2004, at 14:40:02
I'm scheduled to see my pdoc on Monday - haven't seen him since August or so.
I've been doing well, especially after I increased my Lexapro to 15mg/day. That has really made a big difference as I can now say that it is really helping me, I genuinely can say that I am not depressed for the first time in 20 years. I am having trouble with motivation and attention span, restless legs, forgetfulness. I am _easily_ distracted.
I do take Seroquel at night (25-50mg) which has been working great at keeping me asleep. Lately I find that I wake up at 5AM for no reason, and then toss and turn for the next 2 hours and drift in and out of sleep. I do eventually wake up feeling pretty good. I have really been enjoying my music lately, which is a sign that the darkness is lifting.
On days when I get too revved up (afternoon) I take 12.5-25mg of Seroquel, which takes the edge off quite nicely.
To sum up, I am doing much better, but there's still a distance to go before I am satisfied.
What to do about the motivation and the distractibility? I almost feel like I am hyper-active. I can't stay in my chair at work, am always wandering around, jump from topic to topic... I used to have motivation to projects around the house but when I get home I just want to veg out in from of the TV and escape.Any suggestions on adjustments to my meds? I'm hoping for ideas to bounce of my pdoc, who is great.
Thanks in advance
Wildman
Posted by King Vultan on November 12, 2004, at 16:19:52
In reply to Seeing PDOC on Monday, med adjustment suggestions?, posted by Wildman on November 12, 2004, at 14:40:02
> I'm scheduled to see my pdoc on Monday - haven't seen him since August or so.
>
> I've been doing well, especially after I increased my Lexapro to 15mg/day. That has really made a big difference as I can now say that it is really helping me, I genuinely can say that I am not depressed for the first time in 20 years. I am having trouble with motivation and attention span, restless legs, forgetfulness. I am _easily_ distracted.
>
> I do take Seroquel at night (25-50mg) which has been working great at keeping me asleep. Lately I find that I wake up at 5AM for no reason, and then toss and turn for the next 2 hours and drift in and out of sleep. I do eventually wake up feeling pretty good. I have really been enjoying my music lately, which is a sign that the darkness is lifting.
>
> On days when I get too revved up (afternoon) I take 12.5-25mg of Seroquel, which takes the edge off quite nicely.
>
> To sum up, I am doing much better, but there's still a distance to go before I am satisfied.
> What to do about the motivation and the distractibility? I almost feel like I am hyper-active. I can't stay in my chair at work, am always wandering around, jump from topic to topic... I used to have motivation to projects around the house but when I get home I just want to veg out in from of the TV and escape.
>
> Any suggestions on adjustments to my meds? I'm hoping for ideas to bounce of my pdoc, who is great.
>
> Thanks in advance
>
> Wildman
It sounds like your dopamine system is being affected negatively, as you almost have ADHD symptoms, plus your restless legs syndrome is a typical EPSE (extrapyramidal side effect) from blockading dopamine D2 receptors by antipsychotic drugs. I would suggest lowering the Seroquel dosage or perhaps replacing it with another atypical antipsychotic that does not blockade dopamine D2 receptors to the same degree. I believe that what might work better is a drug that more selectively blockades serotonin-2A receptors. Supposedly, this is what Risperdal does at very low dosages, but I have no direct experience with it myself. There may be other atypical antipsychotics that might also be worth considering.Todd
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