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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by gardenergirl on November 5, 2004, at 2:12:09
I am currently taking 60 mg of Nardil spread out over four doses (6 am, 12 pm, 5 pm, and 10 pm). I find I am just exhausted around 4:30ish or five o'clock. At first I thought it was because I needed to eat. I do feel better after eating dinner, which is usually around seven-ish. I took my blood sugar today, and it was 107. Eating a snack at four doesn't always help. I get home and just want to go to sleep. If I do nap, I can sleep til ten at night.
So, could this be Nardil? Any other thoughts or tips? Thanks!
gg
Posted by SLS on November 5, 2004, at 7:39:09
In reply to 5 o'clock fatigue...Nardil?, posted by gardenergirl on November 5, 2004, at 2:12:09
> I am currently taking 60 mg of Nardil spread out over four doses (6 am, 12 pm, 5 pm, and 10 pm). I find I am just exhausted around 4:30ish or five o'clock. At first I thought it was because I needed to eat. I do feel better after eating dinner, which is usually around seven-ish. I took my blood sugar today, and it was 107. Eating a snack at four doesn't always help. I get home and just want to go to sleep. If I do nap, I can sleep til ten at night.
>
> So, could this be Nardil? Any other thoughts or tips? Thanks!
> ggIt most likely is the Nardil. The mechanism behind this daytime sleepiness isn't completely understood, but might be the result of the effect Nardil has on the circadian rhythm. Also, blood pressure tends to ebb around 4:00pm and can sometimes contribute to sleepiness. The simplest solution might be to use caffeine. You might want to try a cup of coffee between 3-4pm. You can optimize caffeine treatment by changing the dosage and the time when you take it. Remember, caffeine is a drug, and you are trying to use it that way. Ideally, you would like to use the minimum necessary to obtain the desired effect. You might build up some tolerance initially, but you will find a stable dosage through experimentation.
- Scott
Posted by gardenergirl on November 6, 2004, at 1:55:33
In reply to Re: 5 o'clock fatigue...Nardil? » gardenergirl, posted by SLS on November 5, 2004, at 7:39:09
Thanks Scott,
I did completely cut out caffeine when I first started on Nardil, but in the last four or five months I've added it back in. The last week I've been so fatigued I've had 3 or 4 cokes in a day, and still really tired.It occurs to me that I started taking Bextra, an NSAID COX-2 inhibitor for some back and knee pain. I take 10 mg once per day, usually sometime between 8 and 11 in the a.m. (Depends on when I eat). Drowsiness and/or fatigue is not listed as a common side effect. Anemia is. Wonder about that. But 800 mg of Motrin also makes me sleepy for some reason. All NSAIDS give me edema, but so far not with Bextra.
Argh, I can either ache or swell and fall asleep every night from 6-10.
gg
Posted by FredPotter on November 7, 2004, at 18:08:17
In reply to Re: 5 o'clock fatigue...Nardil? » SLS, posted by gardenergirl on November 6, 2004, at 1:55:33
I get like this but not always at the same time. I'm on several drugs inc Lithium and Citalopram (Celexa); this one I'm I'm trying to taper off. There's always an inner agitation that goes with the tiredness. It reminds me of when I took Chlorpromazine years ago. I think it's called akathesia. Do you think the Chlor caused permanent damage?
Posted by gardenergirl on November 7, 2004, at 20:26:54
In reply to tiredness and agitation » gardenergirl, posted by FredPotter on November 7, 2004, at 18:08:17
I had that same feeling when I increased my dose from 60 to 75 mg of Nardil. I couldn't stand it, plus it gave me extreme insomnia. I don't know if your experience is a result of the Chlor. Perhpas the Celexa is contributing? Some people react with agitation to SSRI's. I know I did whenever I increased the dose, when I was trying a few.
Good luck,
gg
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