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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by ron1953 on October 4, 2004, at 13:33:16
I remember seeing only one post about the combination. Although I know amphetemine is a big no-no on the MAOI interaction list but I'd like to know who has had success, without BP problems with this combination. The Parnate @ 40mg/day seems to be helping the depression but I miss the help I got from Dex for general lethargy when I was taking other ADs. I was taking 20mg daily, morning only.
Posted by King Vultan on October 4, 2004, at 14:15:46
In reply to Parnate and Dexedrine, posted by ron1953 on October 4, 2004, at 13:33:16
> I remember seeing only one post about the combination. Although I know amphetemine is a big no-no on the MAOI interaction list but I'd like to know who has had success, without BP problems with this combination. The Parnate @ 40mg/day seems to be helping the depression but I miss the help I got from Dex for general lethargy when I was taking other ADs. I was taking 20mg daily, morning only.
I haven't tried this combination myself, but it is not necessarily completely prohibited. In this article
http://www.currentpsychiatry.com/2002_06/06_02_maoi.asp
in the section near the end titled "Avoiding other MAOI-related side effects", they talk about adding d-amphetamine at a starting dosage of 2.5-5 mg/day to raise blood pressure for people suffering hypotension, and the same amount for people suffering from afternoon drowsiness. I believe the implication is that it will definitely raise your blood pressure, but I do not know how much. Perhaps some of the other stimulants they mention might be better choices as far as avoiding this effect.
Todd
Posted by f l y on October 4, 2004, at 14:54:31
In reply to Parnate and Dexedrine, posted by ron1953 on October 4, 2004, at 13:33:16
i took dex w/ parnate and had no adverse effects. i am no longer on parnate.
fly
Posted by ron1953 on October 4, 2004, at 19:23:11
In reply to Re: Parnate and Dexedrine » ron1953, posted by f l y on October 4, 2004, at 14:54:31
What dosages of each were you taking per day?
Posted by jerrympls on October 4, 2004, at 23:18:16
In reply to Re: Parnate and Dexedrine » f l y, posted by ron1953 on October 4, 2004, at 19:23:11
I took Dexedrine with Nardil. The myth of NO stimulants with MAOI's is somewhat comparable to the overblown "cheese effect." HOWEVER - it must be done slowly, at a low dosage and under a doctor's close supervision.
Jerry
Posted by ron1953 on October 5, 2004, at 2:00:26
In reply to Re: Parnate and Dexedrine, posted by jerrympls on October 4, 2004, at 23:18:16
Thanks, Jerry. That supports what I've read elsewhere. Did it help?
Hey, it's good to see you're posting and hopefully out of crisis. I was worried about you.
Ron
Posted by iris2 on October 5, 2004, at 14:46:51
In reply to Parnate and Dexedrine, posted by ron1953 on October 4, 2004, at 13:33:16
I took Ritalin the whole time I took Parnate for BP and fatigue. No problem.
irene
Posted by jerrympls on October 5, 2004, at 19:21:18
In reply to Re: Parnate and Dexedrine » jerrympls, posted by ron1953 on October 5, 2004, at 2:00:26
> Thanks, Jerry. That supports what I've read elsewhere. Did it help?
>
> Hey, it's good to see you're posting and hopefully out of crisis. I was worried about you.
>
> RonHi Ron-
Yes it helped EMENSOUSLY. Thanks for asking about me - nice to know you all are still out there....
Posted by Dave001 on October 6, 2004, at 20:02:50
In reply to Parnate and Dexedrine, posted by ron1953 on October 4, 2004, at 13:33:16
> I remember seeing only one post about the combination. Although I know amphetemine is a big no-no on the MAOI interaction list but I'd like to know who has had success, without BP problems with this combination. The Parnate @ 40mg/day seems to be helping the depression but I miss the help I got from Dex for general lethargy when I was taking other ADs. I was taking 20mg daily, morning only.
I was taking 30 mg/day of Dexedrine when I started Parnate. Never caused any problem, and I could eat whatever I wanted as well. I was on 60 mg/day.
Parnate is really a sh*tty drug. It does seem to improve mood more than the other ADs (certainly better than the SSRIs), but it really wreaks havoc on so many other functions that it's hardly a good long-term solution if you want to perform at your best cognitively and physically.
Dave
Posted by jerrympls on October 6, 2004, at 21:30:16
In reply to Re: Parnate and Dexedrine, posted by Dave001 on October 6, 2004, at 20:02:50
When I first started Nardil, it was a Godsend (within a week!). But I still felt a little unstable - like the bottom was still going to fall out. I got up to the highest dose and it pooped out within a month or two. I had terrible cravings for carbs/sugar at night and had acid reflux so bad I would wake up choking every night - even if I took an antacid (OTC and Rx). Weight gain was bad. My moods started to fluctuate - a coupld days I was just dysthymic and then I would sink and cry and cry and cry. The withdrawl from Nardil almost killed me - mentally. I have never felt such emotional pain in my life. I almost ended it.
I don't mean to post this to scare you or anyone. MAOIs can help tremendously. They just didn't work well for me.
Jerry
Posted by gardenergirl on October 7, 2004, at 3:16:59
In reply to Re: Parnate and Dexedrine, posted by Dave001 on October 6, 2004, at 20:02:50
It sounds like Parnate was not a good choice for you. However calling it a "sh*tty" drug goes a bit far, don't you think? Espcecially given the number of success stories we've seen posted.
In addition, everyone has to make their own decision about what SE's they will/can tolerate in order to have relief from mood disorders. Each person's threshhold and priorities, and what they can and cannot tolerate are unique. Thus, I see no reason why Parnate cannot be a long term solution if it is working satisfactorily for a person.
gg
Posted by ron1953 on October 7, 2004, at 6:33:55
In reply to Re: Parnate and Dexedrine, posted by jerrympls on October 6, 2004, at 21:30:16
BTW, the side-effects of Parnate have been almost non-existent. That's something I couldn't say about any of the anti-depressants I've tried. The lethargy problem existed before I started Parnate.
Posted by iris2 on October 7, 2004, at 9:45:06
In reply to Re: Parnate and Dexedrine, posted by jerrympls on October 6, 2004, at 21:30:16
When I started Parnate it was like a godsend and was for several years until it pooped out. As I wrote before I took Ritalin with it almost the whole time and had no problem. For BP and lethergy.
irene
This is the end of the thread.
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