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Dr. Bob is Robert Hsiung, MD,
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Posted by linkadge on September 27, 2004, at 14:26:21
One mechanism of clonazpam is listed as 5-ht increase. Does this mean more 5-ht reaches the receptors, or does it mean that more accumulates at the axon ???
Linkadge
Posted by linkadge on September 27, 2004, at 14:27:39
In reply to question about clozepam, posted by linkadge on September 27, 2004, at 14:26:21
Basically what im trying to get at this. Does it promote serotogenic activity or depress it. Could it contribute to serotonin syndrome if say, used in conjunction with a MAOI.
Linkadge
Posted by zuzu80 on September 27, 2004, at 16:23:40
In reply to Re: question about clozepam, posted by linkadge on September 27, 2004, at 14:27:39
it means that it enhances serotenergic activity. however, it's not mainly serotonergic, rather it do that as a by product of daily use. i doubt it can cause a serotonin syndrom. i took it with ssri with no problems.
A serotonin syndrom can occur when two drugs that both directly enhance serotenergic transmision, by active mechanism such as Monoamin oxidase inhibitor or by reuptake means.
Posted by linkadge on September 27, 2004, at 21:42:00
In reply to Re: question about clozepam, posted by zuzu80 on September 27, 2004, at 16:23:40
Is what you're saying that benzo's in general raise serotonin activity.
When consulting the webpage:
http://sl.schofield3.home.att.net/medicine/psychiatric_drugs_chart.html
some benzo's have 5ht increase others do not.
Linkadge
This is the end of the thread.
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