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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by aazospiro on July 31, 2004, at 18:13:30
.......in schizophrenics?? I read numerous articles concerning abuse of specific anticholinergic substances used in parkinsons disease by schizophrenics. Apparently produces psychostimulant effects in this population??
Any comments on this.. Seems very strange. Only explanation I can come up with is a secondary central release of DA.....
Makes me wonder if these medications would produce calming + focusing effects in ADHD/ADD individuals.
All comments welcome.
Posted by rod on July 31, 2004, at 21:01:14
In reply to ANTICHOLINERGICS act as psychostimulants ......, posted by aazospiro on July 31, 2004, at 18:13:30
> .......in schizophrenics?? I read numerous articles concerning abuse of specific anticholinergic substances used in parkinsons disease by schizophrenics. Apparently produces psychostimulant effects in this population??
>
> Any comments on this.. Seems very strange. Only explanation I can come up with is a secondary central release of DA.....
>
> Makes me wonder if these medications would produce calming + focusing effects in ADHD/ADD individuals.
>
> All comments welcome.
HiCould you provide a link to a text, because I could not find anything so far. thank you.
Well, I am not schizophrenic, but suffer (have the symptoms) from something like a deficit syndrome (neg. Schizophrenia) without being psychotic.
And I love my Diphenhydramine, which is an anticholinergic antihistaminic drug. It has a sedative, but also activating and vitalising effect for me.
I'd love to hear about maybe better working alternatives.And the explanation you came up with is right in my opinion. At least thats what I know about it. (Acetylcholine - Dopamine "Balance")
Roland
Posted by SLS on July 31, 2004, at 23:38:01
In reply to Re: ANTICHOLINERGICS act as psychostimulants ....., posted by rod on July 31, 2004, at 21:01:14
> And I love my Diphenhydramine, which is an anticholinergic antihistaminic drug. It has a sedative, but also activating and vitalising effect for me.
> I'd love to hear about maybe better working alternatives.
Possibly biperiden (Akineton).
- Scott
Posted by aazospiro on August 1, 2004, at 0:35:07
In reply to Re: ANTICHOLINERGICS act as psychostimulants ....., posted by SLS on July 31, 2004, at 23:38:01
Trihexyphenidyl is the most used. Followed by procyclidine and orphenadrine
Posted by Sad Panda on August 1, 2004, at 4:32:38
In reply to Re: ANTICHOLINERGICS act as psychostimulants ....., posted by SLS on July 31, 2004, at 23:38:01
> > And I love my Diphenhydramine, which is an anticholinergic antihistaminic drug. It has a sedative, but also activating and vitalising effect for me.
> > I'd love to hear about maybe better working alternatives.
>
>
> Possibly biperiden (Akineton).
>
>
> - ScottSome more anticholinergic antihistaminic drugs:
Clozapine
Olanzapine
AmitriptylineCheers,
Panda.
Posted by rod on August 3, 2004, at 14:22:44
In reply to Re: ANTICHOLINERGICS act as psychostimulants ....., posted by aazospiro on August 1, 2004, at 0:35:07
> Trihexyphenidyl is the most used. Followed by procyclidine and orphenadrine
Thank you for posting this
Even the Monograph of Trihexyphenidyl at rxlist.com mentions the possible abuse potential.
" DRUG ABUSE AND DEPENDENCE
Although ARTANE is not classified as a controlled substance, the possibility of abuse should be borne in mind due to its stimulant and euphoriant properties."hmmm, Maybe I talk with my doc about trying this some day...
Roland
This is the end of the thread.
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