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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by AntiTrust on June 3, 2004, at 11:17:04
I have been on lexapro for 6 months-last month the pdoc upped it too 20 mg...doing good w/ it, so I THOUGHT. well I called after hours on friday and left a message that I need something for my panic attacks and such and so.....
they call me back Tuesday...nurse said she talked to therapist and pdoc and they SWITCHED My antidepressant from 40mg LEX to 20mg Celexa!!!
WITh NOTHING FOR MAJOR ANXIETY HELP!!!what the hell is going on here??? does anyone hear me or am i really nutts? I was clear in my message and clear w/ the nurse on the phne what was going on in my head!!!!!
HELP
Posted by MGOLDW on June 3, 2004, at 11:39:08
In reply to Lex to Celexa question, posted by AntiTrust on June 3, 2004, at 11:17:04
Hi! I don't understand. You said that you take 20mg of Lexapro, so how come they want to switch you from 40mg Lex to 20mg Celexa???
I have been on 40mg of Celexa and I am now on 10mg of Lexapro. I am doing OK, except for some mild anxiety...
Posted by Chairman_MAO on June 3, 2004, at 11:39:18
In reply to Lex to Celexa question, posted by AntiTrust on June 3, 2004, at 11:17:04
If you were maintained on 40mg Lexapro, it seems strange to drop down to 20mg of Celexa. That said, lower dosages of citalopram are more effective when treating panic disorder than higher ones. See the following two abstracts:
The effect of citalopram in panic disorder.Wade AG, Lepola U, Koponen HJ, Pedersen V, Pedersen T.
Clydebank Health Centre, Dunbartonshire, Scotland.
BACKGROUND: Citalopram is a serotonin reuptake inhibitor which has been demonstrated to be highly selective and with a superior tolerability profile to the classical tricyclic antidepressants. This study was designed to test whether there was any difference in efficacy in the management of panic disorder (PD) between citalopram and placebo. METHOD: This was a double-blind, placebo and clomipramine controlled, parallel group eight-week study. A total of 475 patients with PD, with or without agoraphobia, were randomised to treatment with either placebo, clomipramine 60 or 90 mg/day, or citalopram 10 or 15 mg/day, or 20 or 30 mg/day, or 40 or 60 mg/day. Doses were increased over the first three weeks, stabilised during the fourth week and fixed between weeks five and eight. RESULTS: Treatment with citalopram at 20 or 30 mg, 40 or 60 mg and clomipramine were significantly superior to placebo, judged by the number of patients free of panic attacks in the week prior to the final assessment. All rating scales examined suggested that citalopram 20 or 30 mg was more effective than citalopram 40 or 60 mg. CONCLUSION: The most advantageous benefit/risk ratio for the treatment of PD was associated with citalopram 20 or 30 mg/day.
Citalopram controls phobic symptoms in patients with panic disorder: randomized controlled trial.
Leinonen E, Lepola U, Koponen H, Turtonen J, Wade A, Lehto H.
Department of Psychogeriatrics, Tampere University Hospital, Finland. esa.leinonen@tays.fi
OBJECTIVE: To examine the effects of long-term treatment with citalopram or clomipramine on subjective phobic symptoms in patients with panic disorder. DESIGN: Double-blind, parallel-group, five-arm study. PATIENTS: Patients aged 18 to 65 years with panic disorder (DMS-III-R diagnosis) and with no major depressive symptoms. INTERVENTIONS: Four hundred and seventy-five patients were randomized to 8 weeks of treatment with either citalopram (10 to 15 mg per day; 20 to 30 mg per day; or 40 to 60 mg per day), clomipramine (60 to 90 mg per day) or placebo. Two hundred and seventy-nine patients continued treatment after the 8-week acute phase. OUTCOME MEASURES: Phobic symptoms were assessed using the Phobia Scale and the Symptom Checklist's (SCL-90) phobia-related factors. RESULTS: At all dosages, citalopram was more efficacious than placebo, with 20 to 30 mg generally being the most effective dosage. Citalopram (20 to 30 mg) generally decreased phobic symptoms significantly more than placebo after Month 3. Interpersonal sensitivity decreased when measured on the respective SCL-90 sub-scale. Alleviation of phobic symptoms generally continued to increase towards the end of the treatment. The effect of clomipramine was not as consistent. CONCLUSIONS: All active treatment groups, especially the group receiving 20 to 30 mg per day of citalopram, effectively controlled phobic symptoms in patients with panic disorder. Long-term treatment with citalopram further decreased phobic symptoms.
Posted by Sebastian on June 3, 2004, at 12:03:35
In reply to Lex to Celexa question, posted by AntiTrust on June 3, 2004, at 11:17:04
what did they do, make a mistake?
Posted by AntiTrust on June 3, 2004, at 13:09:58
In reply to Re: Lex to Celexa question, posted by MGOLDW on June 3, 2004, at 11:39:08
All I can figure out is that it is a mental health center-they treat not only depression etc. but recovering drug/alcoholics so I have come to the conclustion just because I can walk to the office-I think I'd rather drive to a pdoc and get the right HELP! and screw this therapy thing-how do you feel? blah blah why do you think blah blah....I keep a daily journel on how I feel and that helps me enuff now to get the right medical HELP!
thanks for your posts
Posted by AntiTrust on June 3, 2004, at 13:12:01
In reply to Re: Lex to Celexa question » AntiTrust, posted by Chairman_MAO on June 3, 2004, at 11:39:18
I was just at the libary printing about alot of stuff to show the next pdoc or this dork one-and I wish I got this post sooner- Ineed to print out all this too!!!! THANKS!!
This is the end of the thread.
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